2024
Effect of BCG vaccination against Mycobacterium tuberculosis infection in adult Brazilian health-care workers: a nested clinical trial
dos Santos P, Messina N, de Oliveira R, da Silva P, Puga M, Dalcolmo M, dos Santos G, de Lacerda M, Jardim B, de Almeida e Val F, Curtis N, Andrews J, Croda J. Effect of BCG vaccination against Mycobacterium tuberculosis infection in adult Brazilian health-care workers: a nested clinical trial. The Lancet Infectious Diseases 2024, 24: 594-601. PMID: 38423021, PMCID: PMC11111441, DOI: 10.1016/s1473-3099(23)00818-6.Peer-Reviewed Original ResearchConceptsQuantiFERON-TB GoldPlacebo groupEffect of BCG vaccinationBCG vaccinationBCG groupBCG-DenmarkHealth-care workersNegative baseline resultsMonths of treatmentMycobacterium tuberculosis infectionAdult pulmonary tuberculosisQuantiFERON-TBMedian ageRandomised controlled trialsPulmonary tuberculosisNo significant differenceEfficacy outcomesTuberculosis infectionClinical trialsControlled trialsEffect of vaccinationTreatment drugsTuberculosis preventionSubstudySignificant difference
2020
Detection of Drug Resistant Mycobacterium Tuberculosis Strains Using Kit SIRE Nitratase®: a Multicenter Study
de Miranda S, de Almeida I, de Fátima Filardi Oliveira Mansur M, de Assis Figueredo L, da Silva Carvalho W, Hadaad J, do Carmo Guimarães Diniz J, von Groll A, da Silva P, Lopes M, dos Santos M, Brito A, de Queiroz Mello F, da Silva Santos Malaquias T, Croda J, Pinhata J, de Oliveira R, Chimara E, Rossetti M, Halon M, Lourenço M, de Melo Medeiros R, Montes F, Machado D, Viveiros M, Kritski A. Detection of Drug Resistant Mycobacterium Tuberculosis Strains Using Kit SIRE Nitratase®: a Multicenter Study. Brazilian Archives Of Biology And Technology 2020, 63: e20190179. DOI: 10.1590/1678-4324-2020190179.Peer-Reviewed Original ResearchLowenstein-Jensen mediumMulticenter studyProportion methodDrug-resistant Mycobacterium tuberculosis strainsResistant Mycobacterium tuberculosis strainsM. tuberculosis clinical isolatesJensen mediumGold standardTuberculosis clinical isolatesMycobacterium tuberculosis resistanceMycobacterium tuberculosis strainsMiddle-income countriesTreatment drugsTuberculosis strainsClinical isolatesTuberculosis resistanceSusceptibility test kitsEthambutolIncome countriesTest kitIsoniazidRifampicinPresent studyKitStreptomycin