2021
TERT Promoter Mutations Are Enriched in Oral Cavity Cancers and Associated With Locoregional Recurrence
Yu Y, Fan D, Song X, Zakeri K, Chen L, Kang J, McBride S, Tsai CJ, Dunn L, Sherman E, Katabi N, Dogan S, Cracchiolo J, Cohen M, Boyle JO, Lee M, Valero C, Wang J, Wong R, Morris L, Riaz N, Lee N. TERT Promoter Mutations Are Enriched in Oral Cavity Cancers and Associated With Locoregional Recurrence. JCO Precision Oncology 2021, 5: 1259-1269. PMID: 34381934, PMCID: PMC8345918, DOI: 10.1200/po.20.00515.Peer-Reviewed Original ResearchConceptsSquamous cell carcinomaLocoregional failurePatterns of failureCumulative incidenceCell carcinomaPromoter mutationsHPV-positive oropharyngeal squamous cell carcinomaMemorial Sloan-Kettering Cancer CenterRisk of LRFOropharyngeal squamous cell carcinomaNeck squamous cell carcinomaHPV-negative HNSCCsReverse transcriptase (TERT) promoter mutationsOral cavity cancerNext-generation sequencingTERT promoter mutationsDisease subsiteLocoregional recurrenceOverall cohortOverall survivalProspective cohortCancer CenterHuman papillomavirusLaryngopharyngeal cancerUnique pathogenesis
2020
Profiling the Spatial Composition of the Hypoxic Tumor-Immune Microenvironment through Multiplex Immunohistochemistry in a Prospective cohort of HPV Associated Oropharynx Cancer
Chen L, Hollmann T, Li Y, Katabi N, Shah R, Yu Y, Kang J, Tsai C, McBride S, Lee N, Riaz N. Profiling the Spatial Composition of the Hypoxic Tumor-Immune Microenvironment through Multiplex Immunohistochemistry in a Prospective cohort of HPV Associated Oropharynx Cancer. International Journal Of Radiation Oncology • Biology • Physics 2020, 106: 1133. DOI: 10.1016/j.ijrobp.2019.11.363.Peer-Reviewed Original Research