Calcium levels in the Golgi complex regulate clustering and apical sorting of GPI-APs in polarized epithelial cells
Lebreton S, Paladino S, Liu D, Nitti M, von Blume J, Pinton P, Zurzolo C. Calcium levels in the Golgi complex regulate clustering and apical sorting of GPI-APs in polarized epithelial cells. Proceedings Of The National Academy Of Sciences Of The United States Of America 2021, 118: e2014709118. PMID: 34389665, PMCID: PMC8379914, DOI: 10.1073/pnas.2014709118.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCalciumCell PolarityCluster AnalysisDogsEpithelial CellsGene Expression RegulationGene Knockdown TechniquesGolgi ApparatusGPI-Linked ProteinsIonomycinMadin Darby Canine Kidney CellsProtein TransportConceptsApical sortingGPI-APsCholesterol-dependent clusteringGolgi-resident proteinsPlasma membrane organizationPolarized epithelial cellsEpithelial cellsDiverse vital functionsResident proteinsMolecular machinerySecretory cargoMembrane organizationGolgi eventUnexpected roleGolgi complexSpecific machineryGolgiBasolateral surfaceApical surfaceCab45SPCA1Vital functionsMachinerySortingProtein