2024
Association of marital/partner status with hospital readmission among young adults with acute myocardial infarction.
Zhu C, Dreyer R, Li F, Spatz E, Caraballo C, Mahajan S, Raparelli V, Leifheit E, Lu Y, Krumholz H, Spertus J, D'Onofrio G, Pilote L, Lichtman J. Association of marital/partner status with hospital readmission among young adults with acute myocardial infarction. PLOS ONE 2024, 19: e0287949. PMID: 38277368, PMCID: PMC10817183, DOI: 10.1371/journal.pone.0287949.Peer-Reviewed Original ResearchConceptsMarital/partner statusPsychosocial factorsAcute myocardial infarctionYoung adultsHospital dischargeYear of hospital dischargeYoung acute myocardial infarctionAssociated with 1.3-foldCohort of young adultsLong-term readmissionCox proportional hazards modelsStatus interactionSimilar-aged menMyocardial infarctionProportional hazards modelUnpartnered statusPatient interviewsPhysician panelCardiovascular healthHospital readmissionSocioeconomic factorsAMI survivorsSequential adjustmentCardiac readmissionMultiple imputation
2023
Association of Sociodemographic Characteristics With 1-Year Hospital Readmission Among Adults Aged 18 to 55 Years With Acute Myocardial Infarction
Okafor C, Zhu C, Raparelli V, Murphy T, Arakaki A, D’Onofrio G, Tsang S, Smith M, Lichtman J, Spertus J, Pilote L, Dreyer R. Association of Sociodemographic Characteristics With 1-Year Hospital Readmission Among Adults Aged 18 to 55 Years With Acute Myocardial Infarction. JAMA Network Open 2023, 6: e2255843. PMID: 36787140, PMCID: PMC9929697, DOI: 10.1001/jamanetworkopen.2022.55843.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionYoung adultsHospital readmissionBlack raceMyocardial infarctionRacial differencesCardiac factorsSociodemographic characteristicsBlack individualsOdds of readmissionObservational cohort studyMedical record abstractionRisk of readmissionWhite individualsAdults Aged 18Year of dischargePostdischarge readmissionVIRGO StudyCause readmissionCohort studyPrimary outcomeRecord abstractionMulticenter studyAged 18Male ratio
2010
Variation in Recovery
Lichtman JH, Lorenze NP, D'Onofrio G, Spertus JA, Lindau ST, Morgan TM, Herrin J, Bueno H, Mattera JA, Ridker PM, Krumholz HM. Variation in Recovery. Circulation Cardiovascular Quality And Outcomes 2010, 3: 684-693. PMID: 21081748, PMCID: PMC3064946, DOI: 10.1161/circoutcomes.109.928713.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionYoung AMI patientsAMI patientsYoung womenHeart diseaseSex differencesExcess mortality riskIschemic heart diseaseRisk stratification modelPsychosocial risk factorsYears of ageQuality of careComparison cohortPrognostic factorsPrognostic importanceAMI populationMyocardial infarctionRisk factorsObservational studyMortality riskHigh riskAMI eventsPatientsAge accountWomenThe Role of Social Support in Health Status and Depressive Symptoms After Acute Myocardial Infarction
Leifheit-Limson EC, Reid KJ, Kasl SV, Lin H, Jones PG, Buchanan DM, Parashar S, Peterson PN, Spertus JA, Lichtman JH. The Role of Social Support in Health Status and Depressive Symptoms After Acute Myocardial Infarction. Circulation Cardiovascular Quality And Outcomes 2010, 3: 143-150. PMID: 20160162, PMCID: PMC3016989, DOI: 10.1161/circoutcomes.109.899815.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngina PectorisChi-Square DistributionDepressionEvidence-Based MedicineFemaleHealth StatusHealth Status IndicatorsHumansLinear ModelsMaleMiddle AgedMyocardial InfarctionPoisson DistributionProspective StudiesQuality of LifeRegistriesRisk AssessmentRisk FactorsSex FactorsSocial SupportTime FactorsUnited StatesWomen's HealthWomen's Health ServicesConceptsAcute myocardial infarctionLow social supportDisease-specific qualityDepressive symptomsMyocardial infarctionHealth statusPhysical functioningLower disease-specific qualitySocial supportBaseline health statusBaseline depressive symptomsWorse health statusRisk of anginaLower physical functioningMyocardial infarction recoverySex-stratified associationsLower mental functioningSex-stratified analysesMore depressive symptomsFirst yearClinical factorsProspective studyNonsignificant trendSymptomsInfarction
2009
Hospital Arrival Time and Intravenous t-PA Use in US Academic Medical Centers, 2001–2004
Lichtman JH, Watanabe E, Allen NB, Jones SB, Dostal J, Goldstein LB. Hospital Arrival Time and Intravenous t-PA Use in US Academic Medical Centers, 2001–2004. Stroke 2009, 40: 3845-3850. PMID: 19797697, DOI: 10.1161/strokeaha.109.562660.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAgedAged, 80 and overBlack or African AmericanBrain IschemiaEmergency Medical ServicesEmergency Service, HospitalFemaleHealth Services AccessibilityHumansInjections, IntravenousIntracranial ThrombosisMaleMiddle AgedQuality of Health CareSeverity of Illness IndexStrokeThrombolytic TherapyTime FactorsTissue Plasminogen ActivatorTransportation of PatientsUnited StatesWhite PeopleConceptsIschemic stroke patientsSymptom onsetT-PA useStroke patientsHospital arrivalIntravenous tissue-type plasminogen activatorConsecutive ischemic stroke patientsEarly hospital arrivalPercentage of patientsUS academic centersHospital arrival timeRisk-adjusted analysisMultivariate logistic regressionCare-seeking behaviorAcademic medical centerTissue-type plasminogen activatorClinical characteristicsSevere strokePatient characteristicsBlack patientsEmergency departmentMedical recordsHospital careMedical CenterLower oddsDiagnostic Evaluation for Patients with Ischemic Stroke: Are There Sex Differences?
Watanabe E, Allen NB, Dostal J, Sama D, Claus EB, Goldstein LB, Lichtman JH. Diagnostic Evaluation for Patients with Ischemic Stroke: Are There Sex Differences? Cerebrovascular Diseases 2009, 27: 450-455. PMID: 19295208, DOI: 10.1159/000209240.Peer-Reviewed Original ResearchConceptsIschemic stroke patientsStroke patientsIschemic strokeAcademic hospitalDiagnostic evaluationConsecutive ischemic stroke patientsDiagnostic testsAcute coronary symptomsCarotid artery ultrasoundManagement of womenUS academic medical centersMultivariate logistic regressionUse of neuroimagingAcademic medical centerUS academic hospitalsSex-associated differencesSex differencesClinical factorsCoronary symptomsPotential confoundersMedical recordsCarotid arteryMedical CenterPatientsLogistic regressionThe joint contribution of sex, age and type of myocardial infarction on hospital mortality following acute myocardial infarction
Champney K, Frederick P, Bueno H, Parashar S, Foody J, Merz C, Canto J, Lichtman J, Vaccarino V, Investigators F. The joint contribution of sex, age and type of myocardial infarction on hospital mortality following acute myocardial infarction. Heart 2009, 95: 895. PMID: 19147625, PMCID: PMC3065924, DOI: 10.1136/hrt.2008.155804.Peer-Reviewed Original ResearchConceptsNon-ST elevation MIST-elevation MIElevation myocardial infarctionMyocardial infarctionNSTEMI patientsNon-ST elevation myocardial infarctionST-elevation myocardial infarctionRetrospective cohort studyExcess mortality riskShort-term mortalityAcute myocardial infarctionSex-related differencesHospital mortalityUnadjusted RRHospital deathCohort studyPatient ageExcess riskNational registryHospital participantsMAIN OUTCOMEMortality riskOlder womenAge 50Better survival
2001
Utilization of Intravenous Tissue-Type Plasminogen Activator for Ischemic Stroke at Academic Medical Centers
Johnston S, Fung L, Gillum L, Smith W, Brass L, Lichtman J, Brown A. Utilization of Intravenous Tissue-Type Plasminogen Activator for Ischemic Stroke at Academic Medical Centers. Stroke 2001, 32: 1061-1068. PMID: 11340210, DOI: 10.1161/01.str.32.5.1061.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAgedBlack or African AmericanBrain IschemiaCohort StudiesContraindicationsDatabases, FactualDrug Utilization ReviewFemaleFibrinolytic AgentsHumansLogistic ModelsMaleMiddle AgedPatient DischargeStrokeThrombolytic TherapyTissue Plasminogen ActivatorUnited StatesWhite PeopleConceptsAcademic medical centerTissue-type plasminogen activatorIschemic strokeMedical CenterIntravenous tissue-type plasminogen activatorConsecutive ischemic stroke casesAfrican AmericansPlasminogen activatorIschemic stroke patientsUS academic medical centersMultivariable logistic regressionMedical insuranceIschemic stroke casesMedical insurance typePrivate medical insuranceTPA useStroke severityStroke patientsStroke casesMedical historyInsurance typeMedical recordsUnivariate analysisContraindicationsLogistic regressionCan Practice Guidelines Be Transported Effectively to Different Settings? Results from a Multicenter Interventional Study
Lichtman J, Roumanis S, Radford M, Riedinger M, Weingarten S, Krumholz H. Can Practice Guidelines Be Transported Effectively to Different Settings? Results from a Multicenter Interventional Study. The Joint Commission Journal On Quality And Patient Safety 2001, 27: 42-53. PMID: 11147239, DOI: 10.1016/s1070-3241(01)27005-9.Peer-Reviewed Original ResearchMeSH KeywordsAgedChest PainConnecticutFollow-Up StudiesHealth Care SurveysHospitalizationHumansInterviews as TopicMaleMiddle AgedNebraskaNorth CarolinaOutcome Assessment, Health CarePatient DischargePatient SatisfactionPennsylvaniaPractice Guidelines as TopicProspective StudiesSouth CarolinaSurveys and QuestionnairesConceptsChest painClinical guidelinesIntervention periodGuideline adherenceGuideline implementationPatient outcomesLow-risk chest pain patientsLow-risk chest painStandardized protocolMulticenter interventional studyLow-risk patientsChest pain patientsInterventional trialsPain patientsSuccessful translationClinical outcomesGuideline periodInterventional studyPatient satisfactionPatient's physicianPractice guidelinesHospital settingBaseline valuesClinical practicePain