Featured Publications
Critical window variable selection: estimating the impact of air pollution on very preterm birth
Warren JL, Kong W, Luben TJ, Chang HH. Critical window variable selection: estimating the impact of air pollution on very preterm birth. Biostatistics 2019, 21: 790-806. PMID: 30958877, PMCID: PMC7422642, DOI: 10.1093/biostatistics/kxz006.Peer-Reviewed Original ResearchMeSH KeywordsAir PollutantsAir PollutionBayes TheoremFemaleHumansInfant, NewbornMaternal ExposureParticulate MatterPregnancyPremature BirthConceptsHierarchical Bayesian frameworkBayesian frameworkStatistical modelVariable selectionImproved estimationCritical windowPreterm birthRisk parametersVery preterm birthAdverse birth outcomesControl analysisExposure-disease relationshipsDifferent reproductive outcomesBirth outcomesPregnant womenReproductive outcomesCase/control analysisAssessment of critical exposure and outcome windows in time-to-event analysis with application to air pollution and preterm birth study
Chang HH, Warren JL, Darrow LA, Reich BJ, Waller LA. Assessment of critical exposure and outcome windows in time-to-event analysis with application to air pollution and preterm birth study. Biostatistics 2015, 16: 509-521. PMID: 25572998, PMCID: PMC5963471, DOI: 10.1093/biostatistics/kxu060.Peer-Reviewed Original ResearchConceptsPreterm birthAir pollution exposureGestational air pollution exposureRisk of PTBPollution exposurePreterm Birth StudyCourse of pregnancyTime-varying exposureOngoing pregnancyBirth StudyGestational exposureReproductive epidemiologyWeek 30PregnancyWeekly exposureBirth recordsVulnerable periodPopulation studiesPositive associationCritical periodExposureInconsistent findingsAssociationExposure lengthFine particulate matterBayesian multinomial probit modeling of daily windows of susceptibility for maternal PM2.5 exposure and congenital heart defects
Warren JL, Stingone JA, Herring AH, Luben TJ, Fuentes M, Aylsworth AS, Langlois PH, Botto LD, Correa A, Olshan AF, Study B. Bayesian multinomial probit modeling of daily windows of susceptibility for maternal PM2.5 exposure and congenital heart defects. Statistics In Medicine 2016, 35: 2786-2801. PMID: 26853919, PMCID: PMC4899303, DOI: 10.1002/sim.6891.Peer-Reviewed Original ResearchConceptsGestational weeks 2Week 2PM2.5 exposureCongenital heartAmbient air pollution exposureMaternal PM2.5 exposureTetralogy of FallotNational Birth Defect Prevention StudyAir pollution exposureCritical periodDaily PM2.5 exposurePrevention StudyExposure modelEpidemiologic studiesFetal developmentHealth outcomesSignificant associationPollution exposureDay 53PregnancyDay 50Adverse effectsElevated exposureExposureHeart
2024
High ambient temperature in pregnancy and risk of childhood acute lymphoblastic leukaemia: an observational study
Rogne T, Wang R, Wang P, Deziel N, Metayer C, Wiemels J, Chen K, Warren J, Ma X. High ambient temperature in pregnancy and risk of childhood acute lymphoblastic leukaemia: an observational study. The Lancet Planetary Health 2024, 8: e506-e514. PMID: 38969477, PMCID: PMC11260908, DOI: 10.1016/s2542-5196(24)00121-9.Peer-Reviewed Original ResearchConceptsRisk of childhood acute lymphoblastic leukemiaChildhood acute lymphoblastic leukemiaAcute lymphoblastic leukemiaLymphoblastic leukemiaLatino childrenNon-Latino white childrenAssociated with risk of adverse pregnancy outcomesCalifornia Cancer RegistryRisk of acute lymphoblastic leukemiaCalifornia birth recordsRisk of adverse pregnancy outcomesPre-pregnancy periodAssociated with riskBayesian meta-regressionNational Institutes of HealthCancer RegistryCases of childhood acute lymphoblastic leukemiaNational Center for Advancing Translational SciencesAdverse pregnancy outcomesAcute lymphoblastic leukemia casesInstitutes of HealthInvestigation of mechanistic pathwaysBirth recordsGestational weeks 8Pre-pregnancyPreterm and Early-Term Delivery After Heat Waves in 50 US Metropolitan Areas
Darrow L, Huang M, Warren J, Strickland M, Holmes H, Newman A, Chang H. Preterm and Early-Term Delivery After Heat Waves in 50 US Metropolitan Areas. JAMA Network Open 2024, 7: e2412055. PMID: 38787560, PMCID: PMC11127119, DOI: 10.1001/jamanetworkopen.2024.12055.Peer-Reviewed Original ResearchConceptsEarly-term birthPreterm birthCohort studyMetropolitan statistical areasAssociated with pregnancy outcomesEarly-term deliveryRate ratiosRates of pretermYears of ageNational Center for Health StatisticsGestational weeksCenter for Health StatisticsInduced deliveryPregnancy outcomesSingleton birthsPretermSocioeconomically disadvantaged subgroupsUS birthsEligible birthsPerinatal healthEthnic minority groupsBirth recordsConsecutive daysBirthHeat waves
2023
Effects of air pollution on adverse birth outcomes and pregnancy complications in the U.S. state of Kansas (2000–2015)
Hao H, Yoo S, Strickland M, Darrow L, D’Souza R, Warren J, Moss S, Wang H, Zhang H, Chang H. Effects of air pollution on adverse birth outcomes and pregnancy complications in the U.S. state of Kansas (2000–2015). Scientific Reports 2023, 13: 21476. PMID: 38052850, PMCID: PMC10697947, DOI: 10.1038/s41598-023-48329-5.Peer-Reviewed Original ResearchConceptsGestational diabetes mellitusAdverse birth outcomesLow birth weightGestational hypertensionBirth outcomesBirth weightPregnancy complicationsPreterm birthFirst trimesterRisk of GDMMaternal medical complicationsSingleton live birthsWeeks of pregnancyO3 exposureAdverse pregnancyPregnancy exposurePregnancy outcomesDiabetes mellitusMedical complicationsAdverse birthThird trimesterNeonatal mortalityResidential census tractsSocio-economic status factorsDiscrete-time survivalSeason of Conception and Risk of Cerebral Palsy
Zhuo H, Ritz B, Warren J, Liew Z. Season of Conception and Risk of Cerebral Palsy. JAMA Network Open 2023, 6: e2335164. PMID: 37738049, PMCID: PMC10517373, DOI: 10.1001/jamanetworkopen.2023.35164.Peer-Reviewed Original ResearchMeSH KeywordsAdultCerebral PalsyChildCohort StudiesFemaleHumansInfant, NewbornMaleMothersPremature BirthSeasonsConceptsCerebral palsySeason of conceptionCalifornia birth recordsCohort studyPreterm birthRelative riskBirth recordsRisk of CPStatewide cohort studyEtiological risk factorsHigher Social Vulnerability IndexLength of gestationDiagnostic recordsNeighborhood-level factorsSummer conceptionsRisk factorsStratified analysisLive birthsMAIN OUTCOMEHigh riskCP riskPoisson regressionCP statusDevelopmental servicesNeuromotor disabilitiesConfounding by Conception Seasonality in Studies of Temperature and Preterm Birth: A Simulation Study
Huang M, Strickland M, Richards M, Warren J, Chang H, Darrow L. Confounding by Conception Seasonality in Studies of Temperature and Preterm Birth: A Simulation Study. Epidemiology 2023, 34: 439-449. PMID: 36719763, PMCID: PMC10993929, DOI: 10.1097/ede.0000000000001588.Peer-Reviewed Original Research
2017
Investigating the Impact of Maternal Residential Mobility on Identifying Critical Windows of Susceptibility to Ambient Air Pollution During Pregnancy
Warren JL, Son JY, Pereira G, Leaderer BP, Bell ML. Investigating the Impact of Maternal Residential Mobility on Identifying Critical Windows of Susceptibility to Ambient Air Pollution During Pregnancy. American Journal Of Epidemiology 2017, 187: 992-1000. PMID: 29053768, PMCID: PMC5928458, DOI: 10.1093/aje/kwx335.Peer-Reviewed Original ResearchConceptsLow birth weightTerm low birth weightMaternal residential mobilityBirth weightCritical windowBirth cohortWeekly exposurePregnancy week 16Adverse birth outcomesWindow of susceptibilityAmbient air pollutionPregnancy windowsBirth outcomesWeek 16Mother's residencePM10 exposurePregnancyResidential addressesExposure misclassificationDisease developmentCohortAir pollutionExposureAerodynamic diameterPossible mechanism