The calcium-sensing receptor regulates PTHrP production and calcium transport in the lactating mammary gland
Ardeshirpour L, Dann P, Pollak M, Wysolmerski J, VanHouten J. The calcium-sensing receptor regulates PTHrP production and calcium transport in the lactating mammary gland. Bone 2005, 38: 787-793. PMID: 16377269, DOI: 10.1016/j.bone.2005.11.009.Peer-Reviewed Original ResearchConceptsCalcium-sensing receptorPTHrP productionMammary epithelial cellsMammary glandCalcium transportEpithelial cellsCalcium homeostasisParathyroid hormone-related proteinParathyroid hormone secretionProduction of PTHrPHormone-related proteinSystemic calcium homeostasisExtracellular calcium ionsTransepithelial calcium transportG protein-coupled receptorsHormone secretionParathyroid glandsBone massCalcium handlingRenal tubulesTransient lossGlandGenetic confirmationReceptorsSecretionMaternal calcium and bone metabolism during lactation
VanHouten J. Maternal calcium and bone metabolism during lactation. Current Opinion In Endocrinology Diabetes And Obesity 2005, 12: 477-482. DOI: 10.1097/01.med.0000185780.49783.84.Peer-Reviewed Original ResearchParathyroid hormone-related proteinHormone-related proteinMaternal bone mineral densityBone mineral densityCalcium-sensing receptorBone metabolismMammary glandMineral densityParathyroid hormone-related protein levelsMaternal bone metabolismMaternal calcium homeostasisLow estrogen levelsPurpose of reviewParathyroid hormone-related protein geneMaternal calciumEstrogen deficiencyBone lossEstrogen levelsEstrogen treatmentParathyroid glandsMammary epithelial cellsCalcium homeostasisSkeletal calciumSelective deletionTransient loss