2014
Deletion of the Nuclear Localization Sequences and C-Terminus of PTHrP Impairs Embryonic Mammary Development but also Inhibits PTHrP Production
Boras-Granic K, Dann P, VanHouten J, Karaplis A, Wysolmerski J. Deletion of the Nuclear Localization Sequences and C-Terminus of PTHrP Impairs Embryonic Mammary Development but also Inhibits PTHrP Production. PLOS ONE 2014, 9: e90418. PMID: 24785493, PMCID: PMC4006745, DOI: 10.1371/journal.pone.0090418.Peer-Reviewed Original ResearchConceptsMammary gland developmentType 1 PTH/PTHrP receptorC-terminusEmbryonic mammary gland developmentPTH/PTHrP receptorGland developmentPTHrP mRNA levelsNuclear localization signalNuclear localization sequenceHormone-related proteinEmbryonic mammary developmentMammary epithelial cellsLocalization signalNuclear functionsPTHrP productionPTHrP receptorAlternative animal modelLocalization sequencePTHR1 geneAnimal modelsEndocrine fashionMutant formsPTHrPDevelopmental defectsMesenchyme differentiation
2012
Lactation and Neonatal Nutrition: Defining and Refining the Critical Questions
Neville MC, Anderson SM, McManaman JL, Badger TM, Bunik M, Contractor N, Crume T, Dabelea D, Donovan SM, Forman N, Frank DN, Friedman JE, German JB, Goldman A, Hadsell D, Hambidge M, Hinde K, Horseman ND, Hovey RC, Janoff E, Krebs NF, Lebrilla CB, Lemay DG, MacLean PS, Meier P, Morrow AL, Neu J, Nommsen-Rivers LA, Raiten DJ, Rijnkels M, Seewaldt V, Shur BD, VanHouten J, Williamson P. Lactation and Neonatal Nutrition: Defining and Refining the Critical Questions. Journal Of Mammary Gland Biology And Neoplasia 2012, 17: 167-188. PMID: 22752723, PMCID: PMC3428522, DOI: 10.1007/s10911-012-9261-5.Peer-Reviewed Original ResearchConceptsHuman milk compositionMammary gland developmentGestational diabetesObese mothersPreterm infantsUndernourished mothersMaternal nutritionNeonatal nutritionHuman milkInfant nutritionNeonatal developmentSpecific nutritional challengesSpecific training recommendationsMammary developmentUnanswered questionsHuman lactationMetabolic statusInfantsTherapeutic drugsGland developmentNutritional challengesImportant unanswered questionsMilk componentsBehavioral phenotypesLactation