2022
Postpartum cervical length as a predictor of subsequent preterm birth—novel insights on an old enigma
Lauterbach R, Bachar G, Ben-David C, Justman N, Siegler Y, Tzur L, Copel JA, Weiner Z, Beloosesky R, Ginsberg Y. Postpartum cervical length as a predictor of subsequent preterm birth—novel insights on an old enigma. American Journal Of Obstetrics And Gynecology 2022, 228: 461.e1-461.e8. PMID: 36265677, DOI: 10.1016/j.ajog.2022.10.012.Peer-Reviewed Original ResearchMeSH KeywordsCervical Length MeasurementCervix UteriFemaleHumansInfant, NewbornPostpartum PeriodPregnancyPregnancy Trimester, SecondPremature BirthProspective StudiesConceptsSpontaneous preterm birthSubsequent spontaneous preterm birthCervical lengthCervical length measurementPreterm birthPreterm birth groupGestational ageHours postpartumWeeks postpartumTerm groupBirth groupShort cervical lengthSubsequent preterm birthAdverse perinatal outcomesMaternal risk factorsProspective cohort studySingle tertiary centerGroup of patientsPhase 1Perinatal outcomesCohort studyTerm deliveryTertiary centerSubsequent pregnancyPostpartum period
2002
Midtrimester nuchal thickness and the prediction of postnatal congenital heart defect
Bahado-Singh RO, Rowther M, Bailey J, Copel J, Mendilcioglu I, Choi S, Oz U. Midtrimester nuchal thickness and the prediction of postnatal congenital heart defect. American Journal Of Obstetrics And Gynecology 2002, 187: 1250-1253. PMID: 12439514, DOI: 10.1067/mob.2002.128025.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsArea Under CurveFemaleHeart Defects, CongenitalHumansMedical RecordsNeckPregnancyPregnancy Trimester, SecondPrognosisRisk AssessmentRisk FactorsUltrasonography, PrenatalConceptsNuchal thickness measurementPrediction of CHDNuchal thicknessRisk factorsHeart defectsStepwise logistic regression analysisBackground population riskIndividual patient's riskEpidemiologic risk factorsSignificant risk factorsMultiple risk factorsPatient-specific riskSignificant predictorsLogistic regression analysisCongenital heart defectsOnly significant predictorMajor CHDPostnatal evaluationPatient riskMidtrimester fetusesNormal fetusesCongenital heartCHDLogistic regression
2001
Transvaginal sonographic evaluation of fetal anatomy at 14 to 16 weeks. Why it is not feasible in the United States.
Copel J. Transvaginal sonographic evaluation of fetal anatomy at 14 to 16 weeks. Why it is not feasible in the United States. Journal Of Ultrasound In Medicine 2001, 20: 710-711. PMID: 11444728, DOI: 10.7863/jum.2001.20.7.710.Commentaries, Editorials and Letters
2000
Combined ultrasound biometry, serum markers and age for Down syndrome risk estimation
Bahado‐Singh R, Oz A, Gomez K, Hunter D, Copel J, Baumgarten A, Mahoney M. Combined ultrasound biometry, serum markers and age for Down syndrome risk estimation. Ultrasound In Obstetrics And Gynecology 2000, 15: 199-204. PMID: 10846774, DOI: 10.1046/j.1469-0705.2000.00071.x.Peer-Reviewed Original ResearchConceptsMaternal ageAlpha-fetoproteinTriple screenSerum markersUltrasound biometryDown syndromeNuchal thickness measurementMedian maternal ageSerum alpha-fetoproteinNormal singleton pregnanciesHumerus lengthGestational age rangeDown's syndrome screening efficiencySingleton pregnanciesReferral populationFalse positive rateSecond trimesterIndividual Down syndrome oddsFetal biometryUnconjugated estriolStudy groupNuchal thicknessDown syndrome risk estimationHCGAge range
1999
Prenatal Screening for Down's Syndrome — A Search for the Family's Values
Copel J, Bahado-Singh R. Prenatal Screening for Down's Syndrome — A Search for the Family's Values. New England Journal Of Medicine 1999, 341: 521-522. PMID: 10441609, DOI: 10.1056/nejm199908123410709.Commentaries, Editorials and LettersGestational age standardized nuchal thickness values for estimating mid‐trimester Down's syndrome risk
Bahado‐Singh R, Oz U, Kovanci E, Deren O, Feather M, Hsu C, Copel J, Mahoney M. Gestational age standardized nuchal thickness values for estimating mid‐trimester Down's syndrome risk. The Journal Of Maternal-Fetal Medicine 1999, 8: 37-43. PMID: 10090488, DOI: 10.1002/(sici)1520-6661(199903/04)8:2<37::aid-mfm1>3.0.co;2-p.Peer-Reviewed Original Research
1998
New Down syndrome screening algorithm: Ultrasonographic biometry and multiple serum markers combined with maternal age
Bahado-Singh R, Oz A, Kovanci E, Deren O, Copel J, Baumgarten A, Mahoney J. New Down syndrome screening algorithm: Ultrasonographic biometry and multiple serum markers combined with maternal age. American Journal Of Obstetrics And Gynecology 1998, 179: 1627-1631. PMID: 9855608, DOI: 10.1016/s0002-9378(98)70036-5.Peer-Reviewed Original ResearchConceptsHumerus length measurementsSerum markersDown syndromeMaternal ageTriple screenHumerus lengthMultiple stepwise logistic regression analysisTriple-marker serum screeningSerum analytesStepwise logistic regression analysisScreening algorithmHigh-risk populationFetal Down syndromeMultiple serum markersDown syndrome screeningHuman chorionic gonadotropinLogistic regression analysisNew screening algorithmDown's syndrome screening efficiencyPrenatal Down syndrome screeningDown syndrome detectionFalse positive rateSerum screenSingleton fetusesUnconjugated estriolNew triple screen test for Down syndrome: Combined urine analytes and serum AFP
Bahado‐Singh R, Oz U, Kovanci E, Cermik D, Flores D, Copel J, Mahoney M, Cole L. New triple screen test for Down syndrome: Combined urine analytes and serum AFP. The Journal Of Maternal-Fetal Medicine 1998, 7: 111-114. PMID: 9642606, DOI: 10.1002/(sici)1520-6661(199805/06)7:3<111::aid-mfm2>3.0.co;2-n.Peer-Reviewed Original ResearchConceptsSerum AFPIndividual Down syndrome oddsMaternal ageTriple screenUrine beta-core fragmentDown syndromeTriple testTriple screen testBeta-core fragmentDown syndrome casesNeural tube defectsDown's syndrome likelihood ratiosEstriol levelsLarge trialsSecond trimesterUrine testsPositive rateEstriol ratioSyndrome casesTube defectsScreen testFalse positive rateAFP dataUrine analytesAFPSubtle ultrasonographic anomalies: Do they improve the Down syndrome detection rate?
Deren O, Mahoney M, Copel J, Bahado-Singh R. Subtle ultrasonographic anomalies: Do they improve the Down syndrome detection rate? American Journal Of Obstetrics And Gynecology 1998, 178: 441-445. PMID: 9539505, DOI: 10.1016/s0002-9378(98)70417-x.Peer-Reviewed Original ResearchMeSH KeywordsAbnormalities, MultipleAnthropometryCerebral VentriclesDown SyndromeFemaleFingersHumansIntestinesKidney PelvisPredictive Value of TestsPregnancyPregnancy Trimester, SecondProspective StudiesStatistics as TopicUltrasonography, Doppler, ColorUltrasonography, Doppler, TranscranialUltrasonography, PrenatalGlycosylated Hemoglobin in Insulin-Dependent Diabetes Mellitus Related to Preeclampsia
Hsu C, Hong S, Nickless N, Copel J. Glycosylated Hemoglobin in Insulin-Dependent Diabetes Mellitus Related to Preeclampsia. American Journal Of Perinatology 1998, 15: 199-202. PMID: 9572378, DOI: 10.1055/s-2007-993926.Peer-Reviewed Original ResearchMeSH KeywordsDiabetes Mellitus, Type 1FemaleGlycated HemoglobinHumansPre-EclampsiaPregnancyPregnancy in DiabeticsPregnancy Trimester, FirstPregnancy Trimester, SecondRetrospective StudiesConceptsIDDM pregnant womenMean HbA1c valuesIncidence of preeclampsiaHbA1c valuesPregnant womenGestational periodExact testInsulin-dependent diabetes mellitusHigher mean HbA1cPathogenesis of preeclampsiaWeeks of gestationFisher's exact testDifferent gestational periodsNormal mean valueIDDM pregnanciesMean HbA1cDiabetes mellitusWeeks' gestationGlycosylated hemoglobinInsulin-DependentRetrospective studyTrophoblastic invasionMedical recordsPreeclampsiaHigh incidence
1996
Ultrasonographically adjusted midtrimester risk of trisomy 21 and significant chromosomal defects in advanced maternal age
Bahado-Singh R, Deren Ö, Tan A, D'Ancona R, Hunter D, Copel J, Mahoney M. Ultrasonographically adjusted midtrimester risk of trisomy 21 and significant chromosomal defects in advanced maternal age. American Journal Of Obstetrics And Gynecology 1996, 175: 1563-1568. PMID: 8987942, DOI: 10.1016/s0002-9378(96)70107-2.Peer-Reviewed Original ResearchMeSH KeywordsBiometryChromosome AberrationsChromosome DisordersDown SyndromeFemaleHumansMaternal AgePregnancyPregnancy Trimester, SecondPregnancy, High-RiskRisk FactorsUltrasonography, PrenatalConceptsAdvanced maternal ageMaternal ageDown syndromeNormal ultrasonographyUltrasonography resultsAbdominal circumferenceNuchal thicknessAnatomic defectsChromosomal defectsSmaller abdominal circumferenceChoroid plexus cystsFetal Down syndromeReceiver operator characteristic curveStepwise logistic regressionAbnormal ultrasonography resultsBasis of ageDown syndrome detectionUltrasonographic resultsNormal groupChromosome defectsBiparietal diameterRisk tablesTrisomy 21SyndromeShort humerus
1995
Normal nuchal thickness inthe midtrimester indicates reduced risk of Down syndrome in pregnancies with abnormal triple-screen results
Bahado-Singh R, Goldstein I, Uerpairojkit B, Copel J, Mahoney M, Baumgarten A. Normal nuchal thickness inthe midtrimester indicates reduced risk of Down syndrome in pregnancies with abnormal triple-screen results. American Journal Of Obstetrics And Gynecology 1995, 173: 1106-1110. PMID: 7485301, DOI: 10.1016/0002-9378(95)91334-3.Peer-Reviewed Original ResearchConceptsAbnormal triple-screen resultsTriple-screen resultsNuchal thicknessDown syndromeHuman chorionic gonadotropin levelsNuchal thickness measurementChorionic gonadotropin levelsReceiver operator characteristic curveNumber of amniocentesesReceiver operator characteristic plotsRisk thresholdMidtrimester pregnancyGonadotropin levelsWeeks' gestationMaternal ageConsecutive fetusesUnconjugated estriolSerum screeningEuploid fetusesAlpha-fetoproteinSyndromeTrisomy 21Screen resultsRisk estimatesFetuses
1993
Sonographic appearance of craniofacial dysostosis (Crouzon syndrome) in the second trimester
Gollin Y, Abuhamad A, Inati M, Shaffer W, Copel J, Hobbins J. Sonographic appearance of craniofacial dysostosis (Crouzon syndrome) in the second trimester. Journal Of Ultrasound In Medicine 1993, 12: 625-628. PMID: 8246343, DOI: 10.7863/jum.1993.12.10.625.Peer-Reviewed Case Reports and Technical NotesCraniofacial DysostosisFemaleFetal DiseasesHumansPregnancyPregnancy Trimester, SecondUltrasonography, Prenatal
1992
Fetuses with Down syndrome have disproportionately shortened frontal lobe dimensions on ultrasonographic examination
Bahado-Singh R, Wyse L, Dorr M, Copel J, O'Connor T, Hobbins J. Fetuses with Down syndrome have disproportionately shortened frontal lobe dimensions on ultrasonographic examination. American Journal Of Obstetrics And Gynecology 1992, 167: 1009-1014. PMID: 1415385, DOI: 10.1016/s0002-9378(12)80029-9.Peer-Reviewed Original ResearchMeSH KeywordsDown SyndromeFemaleFrontal LobeGestational AgeHumansMathematicsPregnancyPregnancy Trimester, SecondSensitivity and SpecificityThalamusUltrasonography, PrenatalConceptsDown syndrome fetusesSyndrome fetusesFrontothalamic distanceDown syndromePositive predictive valueWeeks' gestationGestational ageNormal medianPosterior thalamusUltrasonographic examinationGroup 52Normal fetusesFrontal lobePredictive valueInner tableFetusesFrontal boneMedianGestationMean valueSyndrome