2020
Treatment and outcome of 370 cases with spontaneous or post‐laser twin anemia–polycythemia sequence managed in 17 fetal therapy centers
Tollenaar L, Slaghekke F, Lewi L, Ville Y, Lanna M, Weingertner A, Ryan G, Arévalo S, Khalil A, Brock C, Klaritsch P, Hecher K, Gardener G, Bevilacqua E, Kostyukov K, Bahtiyar M, Kilby M, Tiblad E, Oepkes D, Lopriore E, Middeldorp J, Haak M, Klumper F, Akkermans J, Delagrange H, Pandya V, Faiola S, Favre R, Hobson S, Rodo C, Thilaganathan B, Papanna R, Greimel P, de Sousa M, Carlin A, Gladkova K, Copel J. Treatment and outcome of 370 cases with spontaneous or post‐laser twin anemia–polycythemia sequence managed in 17 fetal therapy centers. Ultrasound In Obstetrics And Gynecology 2020, 56: 378-387. PMID: 32291846, PMCID: PMC7497010, DOI: 10.1002/uog.22042.Peer-Reviewed Original ResearchConceptsTwin anemia-polycythemia sequenceFetal therapy centersMonochorionic twin pregnanciesPost-laser twin anemia-polycythemia sequenceExpectant management groupSevere neonatal morbidityIntrauterine transfusionExpectant managementPerinatal mortalitySelective feticideTwin pregnanciesLaser surgeryNeonatal morbidityDelivery groupIUT groupDiagnosis of TAPSMiddle cerebral artery peak systolic velocityFetal middle cerebral artery peak systolic velocityBirth intervalLaser surgery groupProlongation of pregnancyTherapy CenterPeak systolic velocityLarge international cohortMedian diagnosis
2014
Doppler abnormalities in monochorionic diamniotic twin pregnancies with discordant growth
Zuckerwise L, Nayeri U, Abdel-Razeq S, Copel J, Bahtiyar M. Doppler abnormalities in monochorionic diamniotic twin pregnancies with discordant growth. Journal Of Perinatology 2014, 35: 387-389. PMID: 25521562, DOI: 10.1038/jp.2014.223.Peer-Reviewed Original ResearchConceptsDoppler flow velocity waveformsFlow velocity waveformsDiscordant growthVelocity waveformsTwin gestationsSmall fetusesAbnormal umbilical artery Doppler flow velocity waveformsUmbilical artery Doppler flow velocity waveformsMonochorionic diamniotic twin gestationsMonochorionic diamniotic twin pregnanciesNeonatal intensive care unitDiamniotic twin gestationsMCDA twin pairsDiamniotic twin pregnanciesEnd-diastolic flowLow Apgar scoreBirth weight discordanceDiscordant fetal growthIntensive care unitTwin transfusion syndromeDoppler velocity waveformsT-testElectronic medical recordsTwin pairsStudent's t-test
2008
Prenatal Course of Isolated Muscular Ventricular Septal Defects Diagnosed Only by Color Doppler Sonography
Bahtiyar MO, Dulay AT, Weeks BP, Friedman AH, Copel JA. Prenatal Course of Isolated Muscular Ventricular Septal Defects Diagnosed Only by Color Doppler Sonography. Journal Of Ultrasound In Medicine 2008, 27: 715-720. PMID: 18424646, DOI: 10.7863/jum.2008.27.5.715.Peer-Reviewed Original ResearchMeSH KeywordsCohort StudiesDown SyndromeEchocardiographyFemaleFetal DevelopmentFetal DiseasesFetal HeartFollow-Up StudiesGestational AgeHeart Septal Defects, VentricularHumansInfant, NewbornNuchal Translucency MeasurementPregnancyPregnancy OutcomeProspective StudiesRisk AssessmentTripletsTwinsUltrasonography, Doppler, ColorUltrasonography, PrenatalConceptsVentricular septal defectColor Doppler examinationMuscular VSDDoppler examinationSeptal defectStudy groupIsolated muscular ventricular septal defectTrisomy 21Isolated ventricular septal defectMuscular ventricular septal defectsHigh-resolution ultrasound equipmentCommon congenital heart defectSmall muscular VSDMean gestational ageFetal echocardiographic examinationColor Doppler sonographyCongenital heart defectsPrenatal resolutionTriplet gestationsEchocardiographic examinationGestational ageCounseling patientsPerinatal courseTwin gestationsFirst trimester
2000
Color Doppler imaging of placental masses: differential diagnosis and fetal outcome
Prapas N, Liang R, Hunter D, Copel J, Lu L, Pazkash V, Mari G. Color Doppler imaging of placental masses: differential diagnosis and fetal outcome. Ultrasound In Obstetrics And Gynecology 2000, 16: 559-563. PMID: 11169351, DOI: 10.1046/j.1469-0705.2000.00324.x.Peer-Reviewed Original ResearchConceptsCases of chorioangiomaPlacental massPlacental hemorrhagePremature laborDifferential diagnosisRapid tumor growthColor Doppler imagingColor flow mappingPlacental chorioangiomaFetal outcomesPerinatal outcomesNeonatal deathRetrospective studyDoppler examinationBlood flowChorioangiomaColor DopplerDoppler imagingTumor growthHemorrhageHalf year periodFlow mappingOnly caseDiagnosisSuch masses
1999
Comparison of treatment with fluorinated glucocorticoids to the natural history of autoantibody‐associated congenital heart block: Retrospective review of the research registry for neonatal lupus
Saleeb S, Copel J, Friedman D, Buyon J. Comparison of treatment with fluorinated glucocorticoids to the natural history of autoantibody‐associated congenital heart block: Retrospective review of the research registry for neonatal lupus. Arthritis & Rheumatism 1999, 42: 2335-2345. PMID: 10555029, DOI: 10.1002/1529-0131(199911)42:11<2335::aid-anr12>3.0.co;2-3.Peer-Reviewed Original ResearchConceptsCongenital heart blockSecond-degree blockThird-degree blockGroup B fetusesGroup BGroup AHeart blockAge 4 yearsNeonatal lupusPericardial effusionPleural effusionResearch RegistryFluorinated steroidsAutoantibody-associated congenital heart blockAnti-SSB/La antibodiesAnti-SSA/RoFluorinated glucocorticoidsNatural historyInitial echocardiographic evaluationDuration of pregnancyIntrauterine growth restrictionFirst-degree blockNumber of deathsComparison of treatmentsSteroid therapyThe Doppler cerebroplacental ratio and perinatal outcome in intrauterine growth restriction
Bahado-Singh R, Kovanci E, Jeffres A, Oz U, Deren O, Copel J, Mari G. The Doppler cerebroplacental ratio and perinatal outcome in intrauterine growth restriction. American Journal Of Obstetrics And Gynecology 1999, 180: 750-756. PMID: 10076158, DOI: 10.1016/s0002-9378(99)70283-8.Peer-Reviewed Original ResearchConceptsIntrauterine growth restrictionDoppler cerebroplacental ratioPerinatal outcomesCerebroplacental ratioBirth weightGrowth restrictionDoppler examinationUmbilical artery pulsatility index valuesStepwise logistic regression analysisAbnormal cerebroplacental ratioBrain-sparing effectLast Doppler examinationUmbilical artery DopplerUmbilical artery velocimetryPulsatility index valuesReceiver operator curve characteristicsReceiver operator characteristic curveLogistic regression analysisRegression analysisArtery DopplerPerinatal morbidityPerinatal complicationsWeeks' gestationNormal medianPerinatal problems
1998
Accurate detection of anomalies by routine ultrasonography in an indigent clinic population
Magriples U, Copel J. Accurate detection of anomalies by routine ultrasonography in an indigent clinic population. American Journal Of Obstetrics And Gynecology 1998, 179: 978-981. PMID: 9790383, DOI: 10.1016/s0002-9378(98)70201-7.Peer-Reviewed Original ResearchConceptsVentricular septal defectScreening ultrasonographyRoutine ultrasonographyClinic populationSeptal defectRoutine screening ultrasonographyImmediate neonatal periodTermination of pregnancyPositive predictive valueMisshapen earsNeonatal chartsExtralobar sequestrationGroup of sonographersWeeks' gestationGreat arteriesNeonatal periodRetrospective studyResident clinicUltrasonographic resultsImperforate anusIndigent populationObstetric ultrasonographyFetal monitoringUltrasonographyPredictive valueArterial and venous Doppler velocimetry in the severely growth‐restricted fetus and associations with adverse perinatal outcome
Ozcan T, Sbracia M, d'Ancona R, Copel J, Mari G. Arterial and venous Doppler velocimetry in the severely growth‐restricted fetus and associations with adverse perinatal outcome. Ultrasound In Obstetrics And Gynecology 1998, 12: 39-44. PMID: 9697283, DOI: 10.1046/j.1469-0705.1998.12010039.x.Peer-Reviewed Original ResearchMeSH KeywordsBlood Flow VelocityCerebral ArteriesFemaleFetal Growth RetardationFetusHumansInfant, NewbornPregnancyPregnancy OutcomePrognosisPulsatile FlowReference ValuesSensitivity and SpecificitySignal Processing, Computer-AssistedSurvival RateUltrasonography, Doppler, ColorUltrasonography, PrenatalUmbilical ArteriesUmbilical VeinsConceptsAdverse outcome parametersAdverse perinatal outcomesGrowth-restricted fetusesOutcome parametersApgar scorePerinatal outcomesDuctus venosusPerinatal deathNeonatal intensive care unitSevere intrauterine growth restrictionDuctus venosus Doppler velocimetryAbnormal Doppler velocimetryVenous Doppler velocimetryVenous Doppler waveformsRespiratory distress syndromeMiddle cerebral arteryRetinopathy of prematurityIntensive care unitIntrauterine growth restrictionDays of lifeOnly significant parameterApgar valuesPeriventricular leukomalaciaDistress syndromeFetal demisePrenatal prediction of neonatal outcome in the extremely low-birth-weight infant
Bahado-Singh R, Dashe J, Deren O, Daftary G, Copel J, Ehrenkranz R. Prenatal prediction of neonatal outcome in the extremely low-birth-weight infant. American Journal Of Obstetrics And Gynecology 1998, 178: 462-468. PMID: 9539509, DOI: 10.1016/s0002-9378(98)70421-1.Peer-Reviewed Original ResearchConceptsNeonatal outcomesOverall survivalSevere morbidityGestational ageAbdominal circumferenceBackward stepwise logistic regression analysisStepwise logistic regression analysisSevere neonatal morbiditySignificant independent predictorsAbdominal circumference measurementsLogistic regression analysisObstetric decision makingPrenatal parametersNeonatal morbiditySingleton infantsWeight infantsIndependent predictorsFetal weightNeonatal dataBirth weightWeight pregnanciesObstetric estimatePrenatal predictorsParental counselingCategories of outcomes
1996
PRENATAL DETECTION OF TWO DIFFERENT MONOSOMIC CELL LINES BY CHORIONIC VILLUS SAMPLING
HSU T, LIOU J, COPEL J, MAHONEY M, BREG W, YANG‐FENG T. PRENATAL DETECTION OF TWO DIFFERENT MONOSOMIC CELL LINES BY CHORIONIC VILLUS SAMPLING. Prenatal Diagnosis 1996, 16: 169-172. PMID: 8650129, DOI: 10.1002/(sici)1097-0223(199602)16:2<169::aid-pd819>3.0.co;2-t.Peer-Reviewed Case Reports and Technical Notes
1991
Hypoplastic left heart syndrome: Prenatal diagnosis, clinical profile, and management
Blake D, Copel J, Kleinman C. Hypoplastic left heart syndrome: Prenatal diagnosis, clinical profile, and management. American Journal Of Obstetrics And Gynecology 1991, 165: 529-534. PMID: 1892177, DOI: 10.1016/0002-9378(91)90279-z.Peer-Reviewed Original ResearchConceptsClinical profileExtracardiac malformationsLethal congenital heart defectNeonatal intensive care settingHypoplastic left heart syndromePrenatal diagnosisIntensive care settingCongenital heart defectsPostnatal interventionsDepth counselingHeart syndromeFetal echocardiographyCare settingsNeonatal assessmentUtero diagnosisHeart defectsElective abortionInformed consentPregnancyDiagnosisAssociated geneticMalformationsComplete evaluationInterventionCounselingPerinatal outcome of fetal complete atrioventricular block: A multicenter experience
Schmidt K, Ulmer H, Silverman N, Kleinman C, Copel J. Perinatal outcome of fetal complete atrioventricular block: A multicenter experience. Journal Of The American College Of Cardiology 1991, 17: 1360-1366. PMID: 2016455, DOI: 10.1016/s0735-1097(10)80148-2.Peer-Reviewed Original ResearchConceptsComplete atrioventricular blockBeats/minStructural heart defectsAtrial isomerismAtrioventricular blockVentricular rateAV blockAtrial rateHeart defectsFetal complete atrioventricular blockDiscordant AV connectionsLeft atrial isomerismConnective tissue diseaseNormal cardiac anatomySecond-degree blockComplete AV blockComplex structural heart defectsSlow atrial rateAntinuclear antibodiesPerinatal outcomesAV connectionsMulticenter experienceClinical courseNeonatal deathTissue disease