2021
Utility of routine screening fetal echocardiogram in pregnancies conceived by in vitro fertilization
Bjorkman KR, Bjorkman SH, Ferdman DJ, Sfakianaki AK, Copel JA, Bahtiyar MO. Utility of routine screening fetal echocardiogram in pregnancies conceived by in vitro fertilization. Fertility And Sterility 2021, 116: 801-808. PMID: 34210397, DOI: 10.1016/j.fertnstert.2021.04.035.Peer-Reviewed Original ResearchConceptsFetal echocardiogramIncidence of CHDFetal echocardiographyIVF pregnanciesRisk factorsIVF groupInsignificant ventricular septal defectsLarge tertiary care centerStatewide hospital discharge dataMean gestational ageTertiary care centerCases of CHDHospital discharge dataRoutine prenatal careVentricular septal defectConfidence intervalsPopulation ratesBirth Defects RegistrySignificant CHDMedication exposureCohort studyPulmonary stenosisPrevious pregnancyGestational ageInfant outcomes
2020
Hydroxychloroquine to Prevent Recurrent Congenital Heart Block in Fetuses of Anti-SSA/Ro-Positive Mothers
Izmirly P, Kim M, Friedman DM, Costedoat-Chalumeau N, Clancy R, Copel JA, Phoon CKL, Cuneo BF, Cohen RE, Robins K, Masson M, Wainwright BJ, Zahr N, Saxena A, Buyon JP. Hydroxychloroquine to Prevent Recurrent Congenital Heart Block in Fetuses of Anti-SSA/Ro-Positive Mothers. Journal Of The American College Of Cardiology 2020, 76: 292-302. PMID: 32674792, PMCID: PMC7394202, DOI: 10.1016/j.jacc.2020.05.045.Peer-Reviewed Original ResearchConceptsCongenital heart blockPrimary outcomeSecondary outcomesEndocardial fibroelastosisHeart blockRecurrence of CHBSSA/Ro-positive mothersAnti-SSA/RoMacrophage Toll-like receptorToll-like receptor antagonistsCutaneous neonatal lupusRo-positive mothersGestational weeks 10Toll-like receptorsFetal cardiac diseaseNeonatal lupusPositive mothersSecondary preventionSkin rashPrevious pregnancyTreat analysisClinical evidenceRecurrence rateReceptor antagonistOptimal approach