2022
NAFTNet retrospective report on the treatment of anti-Ro/SSA mediated fetal heart block with dexamethasone
Sunderji S, Peyvandi S, Jaeggi E, Szwast A, Ryan G, Tessier F, Siddiqui S, Cuneo B, Sheth S, Treadwell M, Frommelt M, Turan S, Copel J, Emery S, Rand L, Moon-Grady AJ, Network F. NAFTNet retrospective report on the treatment of anti-Ro/SSA mediated fetal heart block with dexamethasone. The Journal Of Maternal-Fetal & Neonatal Medicine 2022, 35: 9263-9270. PMID: 35014577, DOI: 10.1080/14767058.2022.2025536.Peer-Reviewed Original ResearchConceptsPositive pregnanciesPrimary outcomePregnancy complicationsPregnancy outcomesPremature deliverySecondary outcomesNorth American Fetal Therapy Network (NAFTNet) centersRo/SSA-positive pregnanciesRetrospective multi-center cohort studyAnti-Ro/SSAMulti-center cohort studyFetal heart blockOverall pregnancy complicationsBetter pregnancy outcomesPoor pregnancy outcomesUse of dexamethasoneTerms of efficacyHigh rateFetal dyadsMaternal comorbiditiesAntibody positivityExpectant managementMaternal diseaseNeonatal morbidityPreterm delivery
2020
Treatment and outcome of 370 cases with spontaneous or post‐laser twin anemia–polycythemia sequence managed in 17 fetal therapy centers
Tollenaar L, Slaghekke F, Lewi L, Ville Y, Lanna M, Weingertner A, Ryan G, Arévalo S, Khalil A, Brock C, Klaritsch P, Hecher K, Gardener G, Bevilacqua E, Kostyukov K, Bahtiyar M, Kilby M, Tiblad E, Oepkes D, Lopriore E, Middeldorp J, Haak M, Klumper F, Akkermans J, Delagrange H, Pandya V, Faiola S, Favre R, Hobson S, Rodo C, Thilaganathan B, Papanna R, Greimel P, de Sousa M, Carlin A, Gladkova K, Copel J. Treatment and outcome of 370 cases with spontaneous or post‐laser twin anemia–polycythemia sequence managed in 17 fetal therapy centers. Ultrasound In Obstetrics And Gynecology 2020, 56: 378-387. PMID: 32291846, PMCID: PMC7497010, DOI: 10.1002/uog.22042.Peer-Reviewed Original ResearchConceptsTwin anemia-polycythemia sequenceFetal therapy centersMonochorionic twin pregnanciesPost-laser twin anemia-polycythemia sequenceExpectant management groupSevere neonatal morbidityIntrauterine transfusionExpectant managementPerinatal mortalitySelective feticideTwin pregnanciesLaser surgeryNeonatal morbidityDelivery groupIUT groupDiagnosis of TAPSMiddle cerebral artery peak systolic velocityFetal middle cerebral artery peak systolic velocityBirth intervalLaser surgery groupProlongation of pregnancyTherapy CenterPeak systolic velocityLarge international cohortMedian diagnosis
2019
Gottesfeld-Hohler Memorial Foundation Risk Assessment for Early-Onset Preeclampsia in the United States: Think Tank Summary.
Copel JA, Platt LD, Hobbins JC, Afshar Y, Grechukhina O, Mallampati D, Bromley B, Caughey AB, Grobman W, Han CS, Nicolaides K, Pettker C, Saade G, Sibai B, Simhan H, Sonek J, Werner E, Chescheir N. Gottesfeld-Hohler Memorial Foundation Risk Assessment for Early-Onset Preeclampsia in the United States: Think Tank Summary. Obstetrics And Gynecology 2019, 135: 36-45. PMID: 31809427, DOI: 10.1097/aog.0000000000003582.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsEarly-onset preeclampsiaSubstantial economic burdenCost-effectiveness dataAspirin prophylaxisNeonatal morbidityPreterm preeclampsiaProphylactic usePreventive strategiesEconomic burdenPreeclampsiaCurrent professional guidelinesRisk assessment strategiesRisk assessmentPractice changeDifferent assessment toolsSpecific knowledge gapsAspirinUnited StatesTarget populationConsequent interventionsFeasibility of implementationProfessional guidelinesAssessment toolAvailable literatureRisk
2003
Delivery at 34 weeks is more costly than at 35 weeks in pregnancies with premature rupture of membranes
Magriples U, Crichton R, Ehrenkranz R, Copel J. Delivery at 34 weeks is more costly than at 35 weeks in pregnancies with premature rupture of membranes. The Journal Of Maternal-Fetal & Neonatal Medicine 2003, 14: 22-25. PMID: 14563087, DOI: 10.1080/jmf.14.1.22.25.Peer-Reviewed Original ResearchConceptsPremature ruptureIntensive care unit stayPreterm premature ruptureMother-infant pairsUnit stayMaternal demographicsNeonatal morbidityPreterm PROMSingleton gestationsNeonatal interventionsNeonatal lengthRetrospective studyProspective dataRelative riskDelay of deliveryWeeksDirect costsSignificant differencesPatientsSignificant increaseStayInfantsDeliveryCost of deliveryRupture
1998
Prenatal prediction of neonatal outcome in the extremely low-birth-weight infant
Bahado-Singh R, Dashe J, Deren O, Daftary G, Copel J, Ehrenkranz R. Prenatal prediction of neonatal outcome in the extremely low-birth-weight infant. American Journal Of Obstetrics And Gynecology 1998, 178: 462-468. PMID: 9539509, DOI: 10.1016/s0002-9378(98)70421-1.Peer-Reviewed Original ResearchConceptsNeonatal outcomesOverall survivalSevere morbidityGestational ageAbdominal circumferenceBackward stepwise logistic regression analysisStepwise logistic regression analysisSevere neonatal morbiditySignificant independent predictorsAbdominal circumference measurementsLogistic regression analysisObstetric decision makingPrenatal parametersNeonatal morbiditySingleton infantsWeight infantsIndependent predictorsFetal weightNeonatal dataBirth weightWeight pregnanciesObstetric estimatePrenatal predictorsParental counselingCategories of outcomes
1988
Prevention of Rh isoimmunization and treatment of the compromised fetus.
Grannum P, Copel J. Prevention of Rh isoimmunization and treatment of the compromised fetus. Seminars In Perinatology 1988, 12: 324-35. PMID: 3146812.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsFetal liver functionIntrauterine intravascular transfusionReversal of hydropsCorrection of anemiaWeeks of gestationSevere erythroblastosis fetalisNeonatal exchange transfusionProblems of prematurityNeonatal morbidityErythroblastosis fetalisIntravascular transfusionRh isoimmunizationExchange transfusionLiver functionFetal vasculatureIntravascular treatmentSevere diseaseTreatment teamPrompt correctionCentral veinTreatment centersTransfusionDifficult procedureTreatmentIsoimmunizationThe reversal of hydrops fetalis by intravascular intrauterine transfusion in severe isoimmune fetal anemia
Grannum P, Copel J, Moya F, Scioscia A, Robert J, Winn H, Coster B, Burdine C, Hobbins J. The reversal of hydrops fetalis by intravascular intrauterine transfusion in severe isoimmune fetal anemia. American Journal Of Obstetrics And Gynecology 1988, 158: 914-919. PMID: 3284364, DOI: 10.1016/0002-9378(88)90094-4.Peer-Reviewed Original ResearchConceptsGm/dlIntrauterine intravascular transfusionIntravascular transfusionHematocrit levelsSurvival rateSevere respiratory distress syndromeReversal of hydropsOverall survival rateRespiratory distress syndromeTime of referralIntravascular intrauterine transfusionSevere erythroblastosis fetalisTotal proteinIntrauterine transfusionNeonatal morbidityErythroblastosis fetalisHydropic fetusesDistress syndromeFetal anemiaExchange transfusionNeonatal deathIntraperitoneal transfusionSevere erythroblastosisNewborn periodIntravascular treatment