2020
Fetal Echocardiography
Copel J. Fetal Echocardiography. 2020, 41-47. DOI: 10.1002/9781119635307.ch6.ChaptersCongenital heart diseaseFetal echocardiographyFetal tachycardiaHeart diseaseSignificant congenital heart diseaseReentrant atrial tachycardiaColor Doppler imagingPostnatal echocardiographyExtracardiac anomaliesAtrial tachycardiaAtrial flutterCardiac anomaliesVentricular extrasystolesVentricular tachycardiaFetal arrhythmiasDifferential diagnosisDoppler imagingEchocardiographyTachycardiaEtiological diversityFetal scanRational management strategyMultifactorial fashionArrhythmiasDisease
2015
Protocol 5: Fetal Echocardiography
Copel J. Protocol 5: Fetal Echocardiography. 2015, 48-53. DOI: 10.1002/9781119001256.ch5.Chapters
2007
192: Effect of in vitro fertilization (IVF) on prevalence of congenital heart disease in the united states: A single institution experience
Bahtiyar M, Dulay A, Weeks B, Friedman A, Copel J. 192: Effect of in vitro fertilization (IVF) on prevalence of congenital heart disease in the united states: A single institution experience. American Journal Of Obstetrics And Gynecology 2007, 197: s65. DOI: 10.1016/j.ajog.2007.10.205.Peer-Reviewed Original Research
2004
Indications for Fetal Echocardiography
Small M, Copel J. Indications for Fetal Echocardiography. Pediatric Cardiology 2004, 25: 210-222. PMID: 15360114, DOI: 10.1007/s00246-003-0587-z.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2001
Prenatal diagnosis of congenital heart disease affects preoperative acidosis in the newborn patient
Verheijen P, Lisowski L, Stoutenbeek P, Hitchcock J, Brenner J, Copel J, Kleinman C, Meijboom E, Bennink G. Prenatal diagnosis of congenital heart disease affects preoperative acidosis in the newborn patient. Journal Of Thoracic And Cardiovascular Surgery 2001, 121: 798-803. PMID: 11279423, DOI: 10.1067/mtc.2001.112825.Peer-Reviewed Original ResearchConceptsCongenital heart diseaseHeart diseaseLower base excessHeart obstructionMetabolic acidosisBase excessDuctus-dependent congenital heart diseasePrenatal diagnosisPostnatal diagnosisImproved long-term outcomesGroup of patientsArterial blood gasesLong-term outcomesCause of deathHigher lactate levelsDays of lifePrevention of acidosisSignificant differencesBiventricular repairPreoperative conditionCerebral damageRetrospective studySurgical outcomesPreoperative acidosisBlood gases
2000
The clinical significance of the irregular fetal heart rhythm
Copel J, Liang R, Demasio K, Ozeren S, Kleinman C. The clinical significance of the irregular fetal heart rhythm. American Journal Of Obstetrics And Gynecology 2000, 182: 813-819. PMID: 10764457, DOI: 10.1016/s0002-9378(00)70330-9.Peer-Reviewed Original ResearchConceptsFetal heart rhythmSignificant arrhythmiasHeart rhythmFetal echocardiographyStructural heart diseaseRoutine prenatal careRetrospective reviewFetal echocardiogramPrenatal careHeart diseaseFetal arrhythmiasClinical significanceClinical practiceArrhythmiasAppropriate managementFetusesIrregular rhythmNormal rhythmDifferent fetusesEchocardiographyRhythmImportant proportionLittle informationEchocardiogramNeonates
1997
Does a prenatal diagnosis of congenital heart disease alter short‐term outcome?
Copel J, Tan A, Kleinman C. Does a prenatal diagnosis of congenital heart disease alter short‐term outcome? Ultrasound In Obstetrics And Gynecology 1997, 10: 237-241. PMID: 9383873, DOI: 10.1046/j.1469-0705.1997.10040237.x.Peer-Reviewed Original ResearchConceptsCongenital heart diseaseLength of hospitalizationPrenatal diagnosis groupInitial hospitalizationDiagnosis groupsGroup IBiventricular repairHeart diseaseOutcome measuresGroup IIPrenatal diagnosisLong-term mortality riskYale-New Haven HospitalDuctal-dependent lesionsFatal congenital anomalyStudy entry criteriaSingle ventricle physiologyPrimary outcome measureShort-term outcomesCost of hospitalizationLife-threatening conditionHospital dischargePrimary admissionVentricle physiologyAntenatal cases
1992
Outcome of prenatally detected cardiac malformations
Smythe J, Copel J, Kleinman C. Outcome of prenatally detected cardiac malformations. The American Journal Of Cardiology 1992, 69: 1471-1474. PMID: 1590238, DOI: 10.1016/0002-9149(92)90903-c.Peer-Reviewed Original ResearchConceptsCardiac failureExtracardiac malformationsMajor extracardiac malformationsCongenital heart diseaseCardiac lesionsOptimal counselingNonimmune hydropsElective terminationExtracardiac defectsFetal echocardiographyHeart diseaseCardiac malformationsCardiac defectsChromosomal abnormalitiesMalformationsPrenatal detectionPregnancyPatientsOutcomesEchocardiographyHydropsPrognosisFailureLesionsAbnormalitiesManagement of the Fetus with Cardiac Disease
Baumann P, Copel J, Kleinman C. Management of the Fetus with Cardiac Disease. Ultrasound Quarterly 1992, 10: 57-78. DOI: 10.1097/00013644-199201020-00001.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
1991
Congenital Heart Disease and Fetal Thoracoabdominal Anomalies: Associations in Utero and the Importance of Cytogenetic Analysis
Fogel M, Copel J, Cullen M, Hobbins J, Kleinman C. Congenital Heart Disease and Fetal Thoracoabdominal Anomalies: Associations in Utero and the Importance of Cytogenetic Analysis. American Journal Of Perinatology 1991, 8: 411-416. PMID: 1839950, DOI: 10.1055/s-2007-999427.Peer-Reviewed Original ResearchConceptsCongenital heart diseasePosterior diaphragmatic herniaDuodenal atresiaHeart diseaseExtracardiac malformationsDiaphragmatic herniaFetal echocardiographyNormal cardiac structureFetal echocardiogramMost fetusesPrenatal evaluationAbnormal karyotypeCardiac structureCytogenetic abnormalitiesFetusesAtresiaOmphaloceleNormal karyotypeAbnormalitiesDiseaseEchocardiographyGastroschisisHerniaPrenatal diagnosisMalformationsForamen ovale size in the normal and abnormal human fetal heart: an indicator of transatrial flow physiology
Feit L, Copel J, Kleinman C. Foramen ovale size in the normal and abnormal human fetal heart: an indicator of transatrial flow physiology. Ultrasound In Obstetrics And Gynecology 1991, 1: 313-319. PMID: 12797035, DOI: 10.1046/j.1469-0705.1991.01050313.x.Peer-Reviewed Original ResearchHeart obstructive lesionsLeft heart obstructive lesionsObstructive lesionsColor Doppler studyDoppler studiesForamen ovaleColor flow Doppler studiesNormal cardiac anatomyCongenital heart diseaseRight ventricular developmentNormal flow patternsHuman fetal heartWeeks' gestationVentricular sizeDoppler interrogationFetal echocardiographyHeart diseaseAtrial septumHelpful adjunctNormal fetusesHuman fetusesFetal heartLesionsFetusesCardiac anatomyCan umbilical artery pulsatility index predict the outcome of fetuses with structural heart disease?
Copel J, Hobbins J, Kleinman C. Can umbilical artery pulsatility index predict the outcome of fetuses with structural heart disease? Journal Of Ultrasound In Medicine 1991, 10: 323-326. PMID: 1895374, DOI: 10.7863/jum.1991.10.6.323.Peer-Reviewed Original ResearchConceptsCongenital heart diseaseElevated pulsatility indexPulsatility indexHeart diseaseUmbilical artery PI valuesUmbilical artery pulsatility indexUmbilical artery Doppler waveformsNormal PI valuesArtery pulsatility indexOutcome of fetusesStructural heart diseaseEnd-diastolic velocityWeeks' gestationFatal anomalyCHD fetusesAnomalous fetusesDoppler waveformsFatal diseaseFetusesNormal populationDiseasePI valuesGestationNormal chromosomesLesionsFetal echocardiography in multiple gestations
Copel J, Inati M, Green J, Hobbins J, Keinman C. Fetal echocardiography in multiple gestations. Ultrasound In Obstetrics And Gynecology 1991, 1: 111-114. PMID: 12797084, DOI: 10.1046/j.1469-0705.1991.01020111.x.Peer-Reviewed Original ResearchMultiple gestationsHeart diseaseSets of twinsFetal echocardiographyFetal cardiac defectsMaternal digitalizationWeeks' gestationCongestive failureExtracardiac malformationsCardiac anomaliesFetal echocardiogramLocation of deliveryAnomalous fetusesPatient managementCardiac defectsSets of tripletsGestationKaryotypic abnormalitiesFetusesDiseaseEchocardiographyEchocardiogramPatientsPregnancyAbnormalities
1988
The frequency of aneuploidy in prenatally diagnosed congenital heart disease: An indication for fetal karyotyping
Copel J, Cullen M, Green J, Mahoney M, Hobbins J, Kleinman C. The frequency of aneuploidy in prenatally diagnosed congenital heart disease: An indication for fetal karyotyping. American Journal Of Obstetrics And Gynecology 1988, 158: 409-413. PMID: 3341415, DOI: 10.1016/0002-9378(88)90166-4.Peer-Reviewed Original ResearchConceptsCongenital heart diseaseHeart diseaseFetal heart diseaseFrequency of aneuploidyNeonatal careCardiac anomaliesFetal echocardiogramPediatric literatureFetal karyotypingParental counselingFetal bloodNonviable fetusClinic dataCase identificationChromosomal abnormalitiesFetusesDiseaseAbnormal chromosomesChromosome analysisEchocardiogramInfantsUteroWorkupAbnormalitiesAmniocentesis
1987
Fetal echocardiographic screening for congenital heart disease: The importance of the four-chamber view
Copel J, Pilu G, Green J, Hobbins J, Kleinman C. Fetal echocardiographic screening for congenital heart disease: The importance of the four-chamber view. American Journal Of Obstetrics And Gynecology 1987, 157: 648-655. PMID: 3631166, DOI: 10.1016/s0002-9378(87)80022-4.Peer-Reviewed Original ResearchConceptsCongenital heart diseaseFour-chamber viewHeart diseasePredictive valueRoutine obstetric ultrasound examinationFetal echocardiographic screeningObstetric ultrasound examinationNegative predictive valuePositive predictive valueObstetrical sonographersEchocardiographic screeningUltrasound examinationDiseaseUseful screenAbnormal heartFetusesHeartScreening methodPregnancyAbnormalities
1986
Congenital heart disease and extracardiac anomalies: Associations and indications for fetal echocardiography
Copel J, Pilu G, Kleinman C. Congenital heart disease and extracardiac anomalies: Associations and indications for fetal echocardiography. American Journal Of Obstetrics And Gynecology 1986, 154: 1121-1132. PMID: 2939723, DOI: 10.1016/0002-9378(86)90773-8.Peer-Reviewed Original ResearchMeSH KeywordsAbdominal MusclesAbnormalities, Drug-InducedAbnormalities, MultipleCentral Nervous SystemChromosome AberrationsChromosome DisordersCongenital AbnormalitiesDigestive System AbnormalitiesEchocardiographyFemaleFetal HeartHeart Defects, CongenitalHumansInfant, NewbornPhenylketonuriasPregnancyPregnancy ComplicationsPregnancy in DiabeticsPrenatal DiagnosisRespiratory System AbnormalitiesUrogenital AbnormalitiesConceptsCongenital heart diseaseHeart diseaseExtracardiac anomaliesFetal echocardiographyCardiac evaluationMaternal diabetesNeonatal managementDiaphragmatic herniaDuodenal atresiaPediatric literatureRenal dysplasiaCorpus callosumDifferential diagnosisEsophageal atresiaMeckel-Gruber syndromeReported associationsEchocardiographyPrenatal identificationSystemic defectsDiseaseAtresiaCoexistent defectsAssociationIndicationsDiabetesThe impact of fetal echocardiography on perinatal outcome
Copel J, Kleinman C. The impact of fetal echocardiography on perinatal outcome. Ultrasound In Medicine & Biology 1986, 12: 327-335. PMID: 3716006, DOI: 10.1016/0301-5629(86)90342-x.Peer-Reviewed Original ResearchConceptsCongenital heart diseaseExtracardiac anomaliesFetal echocardiographyStructural cardiac diseaseFour-chamber viewPerinatal outcomesNonimmune hydropsFetal echocardiogramHeart diseaseAbdominal circumferenceRhythm abnormalitiesCardiac diseaseHigh incidencePrenatal evaluationCardiac structureOne-year periodFetusesEchocardiographyAbnormalitiesDiseaseFamily membersLarge groupGravidaeEchocardiogramHydrops
1985
Fetal atrioventricular valve insufficiency associated with nonimmune hydrops: a two-dimensional echocardiographic and pulsed Doppler ultrasound study.
Silverman N, Kleinman C, Rudolph A, Copel J, Weinstein E, Enderlein M, Golbus M. Fetal atrioventricular valve insufficiency associated with nonimmune hydrops: a two-dimensional echocardiographic and pulsed Doppler ultrasound study. Circulation 1985, 72: 825-832. PMID: 3896564, DOI: 10.1161/01.cir.72.4.825.Peer-Reviewed Original ResearchConceptsAtrioventricular valve insufficiencyStructural heart diseaseNonimmune hydropsValve insufficiencyHeart diseaseLow colloid oncotic pressureFetal cardiac failureAtrioventricular valve regurgitationEarly neonatal periodColloid oncotic pressureCardiac ultrasound examinationDoppler ultrasound studiesM-mode echocardiographyEarly postnatal periodVenous hypertensionHydropic fetusesValve regurgitationCardiac failureSupraventricular tachyarrhythmiasNeonatal periodPoor prognosisEleven fetusesMode echocardiographyUltrasound examinationDoppler ultrasound