1999
Nitric Oxide: A Clinically Important Amniotic Fluid Markerto Distinguish Between Intra-Amniotic Mycoplasma and Non-Mycoplasma Infections
Hsu C, Aversa K, Lu L, Meaddough E, Jones D, Bahado-Singh R, Copel J, Lee I. Nitric Oxide: A Clinically Important Amniotic Fluid Markerto Distinguish Between Intra-Amniotic Mycoplasma and Non-Mycoplasma Infections. American Journal Of Perinatology 1999, 16: 161-166. PMID: 10458527, DOI: 10.1055/s-2007-993851.Peer-Reviewed Original ResearchConceptsAmniotic fluid testsIntra-amniotic infectionInterleukin-6Mycoplasma infectionLeukocyte countFluid testsAmniotic fluid creatinine levelsAmniotic fluid glucose levelNitric oxide metabolite concentrationsPositive amniotic fluid cultureInterleukin-6 concentrationsManagement of patientsAmniotic fluid concentrationsAmniotic fluid leukocyte countsAmniotic fluid cultureClinical characteristicsCreatinine levelsPregnant womenClinical managementFluid cultureGlucose levelsClinical importanceUseful markerGriess reagentInfection
1998
Immunohistochemical localization of inducible nitric oxide synthase on human fetal amnion in intra-amniotic infection
Hsu C, Meaddough E, Lu L, Chelouche A, Liang R, Copel J, Parkash V. Immunohistochemical localization of inducible nitric oxide synthase on human fetal amnion in intra-amniotic infection. American Journal Of Obstetrics And Gynecology 1998, 179: 1271-1274. PMID: 9822514, DOI: 10.1016/s0002-9378(98)70145-0.Peer-Reviewed Original ResearchConceptsInducible nitric oxide synthaseIntra-amniotic infectionNitric oxide synthaseFetal amniotic membranesOxide synthaseFetal amnionNitric oxideAmniotic membranePositive amniotic fluid culturePlacental pathologic featuresAmniotic fluid levelsNitric oxide metabolitesAnti-inducible nitric oxide synthaseAmniotic fluid cultureNormal rabbit serumOvarian carcinoma cellsHuman inducible nitric oxide synthaseInfectious productsPathologic featuresOxide metabolitesFluid culturePositive immunostainingRabbit polyclonal antibodyImmunohistochemical localizationFluid levelsThe role of amniotic fluid L-selectin, GRO-α, and interleukin-8 in the pathogenesis of intraamniotic infection
Hsu C, Meaddough E, Aversa K, Copel J. The role of amniotic fluid L-selectin, GRO-α, and interleukin-8 in the pathogenesis of intraamniotic infection. American Journal Of Obstetrics And Gynecology 1998, 178: 428-432. PMID: 9539502, DOI: 10.1016/s0002-9378(98)70414-4.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmniocentesisAmniotic FluidCarboxylic Ester HydrolasesChemokine CXCL1ChemokinesChemokines, CXCChemotactic FactorsCreatinineFemaleGlucoseGrowth SubstancesHumansInfectionsIntercellular Signaling Peptides and ProteinsInterleukin-8Leukocyte CountL-SelectinPregnancyStatistics, NonparametricConceptsSoluble L-selectinIntraamniotic infectionAmniotic fluid levelsInterleukin-8L-selectinPregnant womenRank correlation testFluid levelsAmniotic fluid creatinine levelsPositive amniotic fluid cultureAmniotic fluid glucose concentrationAmniotic fluid leukocytesRupture of membranesAmniotic fluid leukocyte countsMann-Whitney UtestAmniotic fluid testsPotent leukocyte chemoattractantLeukocyte esterase activityAmniotic fluid cultureEnzyme-linked immunoassayPreterm contractionsCreatinine levelsSpearman rank correlation testLeukocyte countFluid cultureDual Roles of Amniotic Fluid Nitric Oxide and Prostaglandin E2 in Preterm Labor with Intra-Amniotic Infection
Hsu C, Meaddough E, Aversa K, Hong S, Lee I, Bahodo-Singh R, Lu L, Copel J. Dual Roles of Amniotic Fluid Nitric Oxide and Prostaglandin E2 in Preterm Labor with Intra-Amniotic Infection. American Journal Of Perinatology 1998, 15: 683-687. PMID: 10333395, DOI: 10.1055/s-2007-999302.Peer-Reviewed Original ResearchConceptsIntra-amniotic infectionNitric oxide metabolitesPreterm labor patientsAmniotic fluid nitric oxide metabolitesProstaglandin E2Preterm laborLabor patientsNitric oxideIntraamniotic infectionAmniotic fluidAmniotic fluid nitric oxidePositive amniotic fluid cultureAmniotic fluid creatinineProinflammatory nitric oxidePro-inflammatory nitric oxideAmniotic fluid concentrationsAmniotic fluid levelsNitric oxide synthaseCyclo-oxygenase-2Amniotic fluid cultureEnzyme-linked immunoassayOxide metabolitesLeukocyte countFluid cultureOxide synthase
1997
Elevated amniotic fluid nitric oxide metabolites and cyclic guanosine 3′,5′-monophosphate in pregnant women with intraamniotic infection
Hsu C, Aversa K, Meaddough E, Lee I, Copel J. Elevated amniotic fluid nitric oxide metabolites and cyclic guanosine 3′,5′-monophosphate in pregnant women with intraamniotic infection. American Journal Of Obstetrics And Gynecology 1997, 177: 793-796. PMID: 9369821, DOI: 10.1016/s0002-9378(97)70270-9.Peer-Reviewed Original ResearchConceptsAmniotic fluid nitric oxide metabolitesNitric oxide metabolitesCyclic guanosine monophosphateIntraamniotic infectionOxide metabolitesPregnant womenLeukocyte esterase activityGuanosine monophosphateLeukocyte countAmniotic fluid nitric oxidePositive amniotic fluid cultureAmniotic fluid glucose concentrationCyclic guanosineCyclic guanosine monophosphate levelsAmniotic fluid levelsRupture of membranesAmniotic fluid Gram stainAmniotic fluid leukocyte countsGuanosine monophosphate levelsAmniotic fluid culturePanel of testsPreterm contractionsEndogenous nitriteFluid cultureFluid levels