2022
Impact of prenatally diagnosed congenital heart defects on outcomes and management
Wong J, Kohari K, Bahtiyar MO, Copel J. Impact of prenatally diagnosed congenital heart defects on outcomes and management. Journal Of Clinical Ultrasound 2022, 50: 646-654. PMID: 35543387, DOI: 10.1002/jcu.23219.Peer-Reviewed Original ResearchConceptsCongenital heart defectsComplex congenital heart defectEarly fetal echocardiographyImproved survival ratesPrenatal detection rateGood psychosocial supportFetal echocardiogramFetal echocardiographyPatient educationCardiology specialistsHigh riskHeart defectsSurvival rateCongenital heartPsychosocial supportEarly detectionPrenatal identificationPrenatal detectionDelivery planningDetection rateUltrasound technologyImportant contributorEchocardiogramEchocardiographyNeonates
2021
Utility of routine screening fetal echocardiogram in pregnancies conceived by in vitro fertilization
Bjorkman KR, Bjorkman SH, Ferdman DJ, Sfakianaki AK, Copel JA, Bahtiyar MO. Utility of routine screening fetal echocardiogram in pregnancies conceived by in vitro fertilization. Fertility And Sterility 2021, 116: 801-808. PMID: 34210397, DOI: 10.1016/j.fertnstert.2021.04.035.Peer-Reviewed Original ResearchConceptsFetal echocardiogramIncidence of CHDFetal echocardiographyIVF pregnanciesRisk factorsIVF groupInsignificant ventricular septal defectsLarge tertiary care centerStatewide hospital discharge dataMean gestational ageTertiary care centerCases of CHDHospital discharge dataRoutine prenatal careVentricular septal defectConfidence intervalsPopulation ratesBirth Defects RegistrySignificant CHDMedication exposureCohort studyPulmonary stenosisPrevious pregnancyGestational ageInfant outcomes
2020
RECONSIDERING AMERICAN HEART ASSOCIATION RECOMMENDATIONS TO PERFORM FETAL ECHOCARDIOGRAM FOR ALL IN-VITRO FERTILIZATION PREGNANCIES: IS THERE A LOW-RISK GROUP?
Bjorkman K, Bjorkman S, Copel J, Bahtiyar M. RECONSIDERING AMERICAN HEART ASSOCIATION RECOMMENDATIONS TO PERFORM FETAL ECHOCARDIOGRAM FOR ALL IN-VITRO FERTILIZATION PREGNANCIES: IS THERE A LOW-RISK GROUP? Journal Of The American College Of Cardiology 2020, 75: 584. DOI: 10.1016/s0735-1097(20)31211-0.Peer-Reviewed Original Research
2019
Fetal Myocardial Function as Assessed by N-Terminal Fragment Brain Natriuretic Protein in Premature Fetuses Exposed to Intra-amniotic Inflammation
Irani RA, Buhimschi CS, Cross SN, Zhao G, Copel JA, Bhandari V, Buhimschi IA, Bahtiyar MO. Fetal Myocardial Function as Assessed by N-Terminal Fragment Brain Natriuretic Protein in Premature Fetuses Exposed to Intra-amniotic Inflammation. American Journal Of Perinatology 2019, 37: 745-753. PMID: 31121635, DOI: 10.1055/s-0039-1688909.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmniocentesisAmniotic FluidBiomarkersChorioamnionitisEchocardiography, DopplerFemaleFetal BloodFetal HeartHumansInfant, NewbornInfant, PrematureInflammationInterleukin-6MaleMass SpectrometryNatriuretic Peptide, BrainPeptide FragmentsPlacentaPregnancyPremature BirthVentricular Function, LeftConceptsIntra-amniotic infection/inflammationBrain natriuretic proteinAmniotic fluidNT-proBNPTei indexNatriuretic proteinVentricular functionFetal exposureCord bloodCord IL-6Intra-amniotic inflammationFetal myocardial functionInfection/inflammationBlood NT-proBNPFetal heart functionNT-proBNP immunoassaysEnzyme-linked immunosorbentGestational agePremature fetusesFetal echocardiogramIL-6Circulatory levelsMyocardial functionHeart functionFetuses
2000
The clinical significance of the irregular fetal heart rhythm
Copel J, Liang R, Demasio K, Ozeren S, Kleinman C. The clinical significance of the irregular fetal heart rhythm. American Journal Of Obstetrics And Gynecology 2000, 182: 813-819. PMID: 10764457, DOI: 10.1016/s0002-9378(00)70330-9.Peer-Reviewed Original ResearchConceptsFetal heart rhythmSignificant arrhythmiasHeart rhythmFetal echocardiographyStructural heart diseaseRoutine prenatal careRetrospective reviewFetal echocardiogramPrenatal careHeart diseaseFetal arrhythmiasClinical significanceClinical practiceArrhythmiasAppropriate managementFetusesIrregular rhythmNormal rhythmDifferent fetusesEchocardiographyRhythmImportant proportionLittle informationEchocardiogramNeonates
1991
Congenital Heart Disease and Fetal Thoracoabdominal Anomalies: Associations in Utero and the Importance of Cytogenetic Analysis
Fogel M, Copel J, Cullen M, Hobbins J, Kleinman C. Congenital Heart Disease and Fetal Thoracoabdominal Anomalies: Associations in Utero and the Importance of Cytogenetic Analysis. American Journal Of Perinatology 1991, 8: 411-416. PMID: 1839950, DOI: 10.1055/s-2007-999427.Peer-Reviewed Original ResearchConceptsCongenital heart diseasePosterior diaphragmatic herniaDuodenal atresiaHeart diseaseExtracardiac malformationsDiaphragmatic herniaFetal echocardiographyNormal cardiac structureFetal echocardiogramMost fetusesPrenatal evaluationAbnormal karyotypeCardiac structureCytogenetic abnormalitiesFetusesAtresiaOmphaloceleNormal karyotypeAbnormalitiesDiseaseEchocardiographyGastroschisisHerniaPrenatal diagnosisMalformationsFetal echocardiography in multiple gestations
Copel J, Inati M, Green J, Hobbins J, Keinman C. Fetal echocardiography in multiple gestations. Ultrasound In Obstetrics And Gynecology 1991, 1: 111-114. PMID: 12797084, DOI: 10.1046/j.1469-0705.1991.01020111.x.Peer-Reviewed Original ResearchMultiple gestationsHeart diseaseSets of twinsFetal echocardiographyFetal cardiac defectsMaternal digitalizationWeeks' gestationCongestive failureExtracardiac malformationsCardiac anomaliesFetal echocardiogramLocation of deliveryAnomalous fetusesPatient managementCardiac defectsSets of tripletsGestationKaryotypic abnormalitiesFetusesDiseaseEchocardiographyEchocardiogramPatientsPregnancyAbnormalities
1988
The frequency of aneuploidy in prenatally diagnosed congenital heart disease: An indication for fetal karyotyping
Copel J, Cullen M, Green J, Mahoney M, Hobbins J, Kleinman C. The frequency of aneuploidy in prenatally diagnosed congenital heart disease: An indication for fetal karyotyping. American Journal Of Obstetrics And Gynecology 1988, 158: 409-413. PMID: 3341415, DOI: 10.1016/0002-9378(88)90166-4.Peer-Reviewed Original ResearchConceptsCongenital heart diseaseHeart diseaseFetal heart diseaseFrequency of aneuploidyNeonatal careCardiac anomaliesFetal echocardiogramPediatric literatureFetal karyotypingParental counselingFetal bloodNonviable fetusClinic dataCase identificationChromosomal abnormalitiesFetusesDiseaseAbnormal chromosomesChromosome analysisEchocardiogramInfantsUteroWorkupAbnormalitiesAmniocentesis
1986
The impact of fetal echocardiography on perinatal outcome
Copel J, Kleinman C. The impact of fetal echocardiography on perinatal outcome. Ultrasound In Medicine & Biology 1986, 12: 327-335. PMID: 3716006, DOI: 10.1016/0301-5629(86)90342-x.Peer-Reviewed Original ResearchConceptsCongenital heart diseaseExtracardiac anomaliesFetal echocardiographyStructural cardiac diseaseFour-chamber viewPerinatal outcomesNonimmune hydropsFetal echocardiogramHeart diseaseAbdominal circumferenceRhythm abnormalitiesCardiac diseaseHigh incidencePrenatal evaluationCardiac structureOne-year periodFetusesEchocardiographyAbnormalitiesDiseaseFamily membersLarge groupGravidaeEchocardiogramHydrops