2000
Combined ultrasound biometry, serum markers and age for Down syndrome risk estimation
Bahado‐Singh R, Oz A, Gomez K, Hunter D, Copel J, Baumgarten A, Mahoney M. Combined ultrasound biometry, serum markers and age for Down syndrome risk estimation. Ultrasound In Obstetrics And Gynecology 2000, 15: 199-204. PMID: 10846774, DOI: 10.1046/j.1469-0705.2000.00071.x.Peer-Reviewed Original ResearchConceptsMaternal ageAlpha-fetoproteinTriple screenSerum markersUltrasound biometryDown syndromeNuchal thickness measurementMedian maternal ageSerum alpha-fetoproteinNormal singleton pregnanciesHumerus lengthGestational age rangeDown's syndrome screening efficiencySingleton pregnanciesReferral populationFalse positive rateSecond trimesterIndividual Down syndrome oddsFetal biometryUnconjugated estriolStudy groupNuchal thicknessDown syndrome risk estimationHCGAge range
1999
A new splenic artery Doppler velocimetric index for prediction of severe fetal anemia associated with Rh alloimmunization
Bahado-Singh R, Oz U, Deren O, Pirhonen J, Kovanci E, Copel J, Onderoglu L. A new splenic artery Doppler velocimetric index for prediction of severe fetal anemia associated with Rh alloimmunization. American Journal Of Obstetrics And Gynecology 1999, 180: 49-54. PMID: 9914577, DOI: 10.1016/s0002-9378(99)70148-1.Peer-Reviewed Original ResearchConceptsMain splenic arterySevere fetal anemiaSevere anemiaHemoglobin deficitFetal anemiaSplenic arteryGestational ageDoppler velocimetric indicesDevelopment of hydropsNew Doppler indexVelocimetric indicesCase patientsDoppler indicesRh alloimmunizationRh sensitizationHealthy fetusesAnemiaFalse positive rateNoninvasive predictionDiastolic phaseAnemia detectionDoppler velocimetrySignificant correlationArteryCordocentesisA high-sensitivity alternative to “routine” genetic amniocentesis: Multiple urinary analytes, nuchal thickness, and age
Bahado-Singh R, Oz U, Kovanci E, Cermik D, Copel J, Mahoney M, Cole L. A high-sensitivity alternative to “routine” genetic amniocentesis: Multiple urinary analytes, nuchal thickness, and age. American Journal Of Obstetrics And Gynecology 1999, 180: 169-173. PMID: 9914599, DOI: 10.1016/s0002-9378(99)70170-5.Peer-Reviewed Original ResearchConceptsAdvanced maternal ageNuchal thicknessMaternal ageGenetic amniocentesisDown syndrome detection rateUrinary beta-core fragmentUrinary analytesMaternal age-related riskRisk thresholdSyndrome detection rateTotal study populationHigh-risk groupAge-related riskBeta-core fragmentRate of amniocentesisHuman chorionic gonadotropinDown syndrome riskDown's syndrome likelihood ratiosDown's syndrome screening efficiencyLikelihood ratioCommon indicationFalse positive rateNormal medianPregnant womenSyndrome risk
1998
New Down syndrome screening algorithm: Ultrasonographic biometry and multiple serum markers combined with maternal age
Bahado-Singh R, Oz A, Kovanci E, Deren O, Copel J, Baumgarten A, Mahoney J. New Down syndrome screening algorithm: Ultrasonographic biometry and multiple serum markers combined with maternal age. American Journal Of Obstetrics And Gynecology 1998, 179: 1627-1631. PMID: 9855608, DOI: 10.1016/s0002-9378(98)70036-5.Peer-Reviewed Original ResearchConceptsHumerus length measurementsSerum markersDown syndromeMaternal ageTriple screenHumerus lengthMultiple stepwise logistic regression analysisTriple-marker serum screeningSerum analytesStepwise logistic regression analysisScreening algorithmHigh-risk populationFetal Down syndromeMultiple serum markersDown syndrome screeningHuman chorionic gonadotropinLogistic regression analysisNew screening algorithmDown's syndrome screening efficiencyPrenatal Down syndrome screeningDown syndrome detectionFalse positive rateSerum screenSingleton fetusesUnconjugated estriolNew triple screen test for Down syndrome: Combined urine analytes and serum AFP
Bahado‐Singh R, Oz U, Kovanci E, Cermik D, Flores D, Copel J, Mahoney M, Cole L. New triple screen test for Down syndrome: Combined urine analytes and serum AFP. The Journal Of Maternal-Fetal Medicine 1998, 7: 111-114. PMID: 9642606, DOI: 10.1002/(sici)1520-6661(199805/06)7:3<111::aid-mfm2>3.0.co;2-n.Peer-Reviewed Original ResearchConceptsSerum AFPIndividual Down syndrome oddsMaternal ageTriple screenUrine beta-core fragmentDown syndromeTriple testTriple screen testBeta-core fragmentDown syndrome casesNeural tube defectsDown's syndrome likelihood ratiosEstriol levelsLarge trialsSecond trimesterUrine testsPositive rateEstriol ratioSyndrome casesTube defectsScreen testFalse positive rateAFP dataUrine analytesAFPNew triple screen test for down syndrome: Combined urine analytes and serum AFP
Bahado-Singh R, Oz U, Kovanci E, Cermik D, Flores D, Copel J, Mahoney M, Cole L. New triple screen test for down syndrome: Combined urine analytes and serum AFP. The Journal Of Maternal-Fetal Medicine 1998, 7: 111-114. DOI: 10.3109/14767059809020424.Peer-Reviewed Original ResearchSerum AFPIndividual Down syndrome oddsMaternal ageTriple screenDown syndromeTriple testTriple screen testΒ-core fragmentDown syndrome casesNeural tube defectsDown's syndrome likelihood ratiosEstriol levelsLarge trialsSecond trimesterUrine testsPositive rateEstriol ratioSyndrome casesTube defectsScreen testFalse positive rateAFP dataUrine analytesAFPSyndrome
1986
The value of serial human chorionic gonadotropin testing as a diagnostic tool in ectopic pregnancy
Romero R, Kadar N, Copel J, Jeanty P, DeCherney A, Hobbins J. The value of serial human chorionic gonadotropin testing as a diagnostic tool in ectopic pregnancy. American Journal Of Obstetrics And Gynecology 1986, 155: 392-394. PMID: 3740163, DOI: 10.1016/0002-9378(86)90838-0.Peer-Reviewed Original ResearchConceptsEctopic pregnancySerial human chorionic gonadotropin determinationsHuman chorionic gonadotropin testingHuman chorionic gonadotropin titersHuman chorionic gonadotropin determinationsSlope of changeIntrauterine pregnancyMIU/Serial titersGonadotropin determinationsCutoff valuePregnancyPatientsTitersDiagnostic toolTime curvePositive rateAbnormal slopeFalse positive rate