2015
Emerging immunotherapies for bladder cancer
Kim JW, Tomita Y, Trepel J, Apolo AB. Emerging immunotherapies for bladder cancer. Current Opinion In Oncology 2015, 27: 191-200. PMID: 25811346, PMCID: PMC7709951, DOI: 10.1097/cco.0000000000000177.Peer-Reviewed Original ResearchConceptsUrothelial carcinomaImmune escapeImmune systemTumor antigen presentationAdvanced urothelial carcinomaBenefit of immunotherapyImmune escape mechanismsFraction of patientsHigh mutational burdenImmune-mediated cytotoxicityMultiple tumor typesDurable responsesImmune checkpointsBladder cancerClinical trialsT cellsCombinatorial regimensTumor antigensMutational burdenImmunotherapyClinical developmentCarcinomaTumor typesTumor cellsEscape mechanisms
2010
Chemoprevention of Head and Neck Cancer with Green Tea Polyphenols
Kim JW, Amin AR, Shin DM. Chemoprevention of Head and Neck Cancer with Green Tea Polyphenols. Cancer Prevention Research 2010, 3: 900-909. PMID: 20663981, PMCID: PMC2917478, DOI: 10.1158/1940-6207.capr-09-0131.Peer-Reviewed Original ResearchConceptsSquamous cell carcinomaGreen tea polyphenolsCell carcinomaNovel clinical trial designsTea polyphenolsChemoprevention of headHigh-risk patientsKey molecular signaling pathwaysClinical trial designNatural dietary compoundsUse of biomarkersMolecular signaling pathwaysNeck cancerChemoprevention researchChemopreventive agentsDietary compoundsTrial designCarcinomaChemopreventionSignaling pathwaysAdditive effectNatural compoundsEGCGMajor advancesPolyphenols