79 Leptospirosis
Vinetz J, Watt G. 79 Leptospirosis. 2020, 636-640. DOI: 10.1016/b978-0-323-55512-8.00079-x.Peer-Reviewed Original ResearchSevere leptospirosisAcute kidney injuryEndothelial cell dysfunctionKey pathologic featuresThird-generation cephalosporinsMarked functional impairmentHigh mortality ratePathogenesis of leptospirosisMost disease transmissionRefractory shockKidney injuryOral doxycyclineParenteral penicillinPulmonary hemorrhageSubstantial morbidityPathologic featuresHistopathologic changesFunctional impairmentAvailable vaccinesCell dysfunctionDiagnostic confirmationRisk populationsMilder casesMortality rateLeptospirosis