Optimization of Plasmodium vivax infection of colonized Amazonian Anopheles darlingi
Andrade A, Santos N, Bastos A, Pontual J, Araújo C, Lima A, Martinez L, Ferreira A, Aguiar A, Teles C, Guido R, Santana R, Lopes S, Medeiros J, Rizopoulos Z, Vinetz J, Campo B, Lacerda M, Araújo M. Optimization of Plasmodium vivax infection of colonized Amazonian Anopheles darlingi. Scientific Reports 2023, 13: 18207. PMID: 37875508, PMCID: PMC10598059, DOI: 10.1038/s41598-023-44556-y.Peer-Reviewed Original ResearchConceptsP. vivax liver stagesPlasmodium vivax infectionPlasmodium vivax sporozoitesLiver stage parasitesP. vivax sporozoitesFemale anopheline mosquitoesVivax infectionLiver stagesHepatocyte infectionVaccine developmentStage parasitesSporozoite viabilityMembrane feeding systemSporozoite productionDrug developmentSporozoitesAnopheline mosquitoesInfectionParasite biologyArtificial membrane feeding systemPatientsSimple centrifugation methodSerum replacementBlood