1994
Extracellular Matrix‐Degrading Proteinases in the Nervous System
Romanic A, Madri J. Extracellular Matrix‐Degrading Proteinases in the Nervous System. Brain Pathology 1994, 4: 145-156. PMID: 8061860, DOI: 10.1111/j.1750-3639.1994.tb00825.x.Peer-Reviewed Original ResearchConceptsCell-ECM interactionsExtracellular matrixMatrix-degrading proteinasesNeuronal cell migrationExtracellular matrix-degrading proteinasesCell migrationNervous systemECM degradationNeurite outgrowthCell proliferationDrug designProteolytic activityNew insightsPathological conditionsBrain tumor growthTumor growthMatrix metalloproteinasesProteinasesForm of therapyCentral nervous systemInhibitorsPlasminogen activatorTraffickingLeukocyte traffickingNerve demyelination
1984
Bronchial Lavage Proteins as Correlates of Histopathologic Airway Changes in Healthy Smokers and Patients with Pulmonary Carcinoma1–4
Merrill W, Barwick K, Madri J, Strober W, Matthay R, Olchowski J, Naegel G, Reynolds H. Bronchial Lavage Proteins as Correlates of Histopathologic Airway Changes in Healthy Smokers and Patients with Pulmonary Carcinoma1–4. American Journal Of Respiratory And Critical Care Medicine 1984, 130: 905-9. PMID: 6208835, DOI: 10.1164/arrd.1984.130.5.905.Peer-Reviewed Original ResearchConceptsFree secretory componentSymptomatic smokersCarcinoma patientsAsymptomatic smokersLavage fluidLung diseaseCancer patientsSmoking-associated lung diseasePacks/yearHigh-risk subgroupsImportant etiologic factorNumber of smokersAirway changesAirway injuryGroups of subjectsHealthy smokersSmoking historyNormal nonsmokersLavage levelsCigarette smokingSmoking populationEtiologic factorsLavage proteinImmunohistochemical evidenceLung sections
1983
Multiple mechanisms of dissociated epidermal cell spreading.
Stenn K, Madri J, Tinghitella T, Terranova V. Multiple mechanisms of dissociated epidermal cell spreading. Journal Of Cell Biology 1983, 96: 63-67. PMID: 6186674, PMCID: PMC2112260, DOI: 10.1083/jcb.96.1.63.Peer-Reviewed Original Research
1982
Differential proteolytic susceptibility of laminin alpha and beta subunits
Rao C, Margulies I, Goldfarb R, Madri J, Woodley D, Liotta L. Differential proteolytic susceptibility of laminin alpha and beta subunits. Archives Of Biochemistry And Biophysics 1982, 219: 65-70. PMID: 6758704, DOI: 10.1016/0003-9861(82)90134-5.Peer-Reviewed Original ResearchIsolation of a subunit of laminin and its role in molecular structure and tumor cell attachment.
Rao C, Margulies I, Tralka T, Terranova V, Madri J, Liotta L. Isolation of a subunit of laminin and its role in molecular structure and tumor cell attachment. Journal Of Biological Chemistry 1982, 257: 9740-9744. PMID: 7107589, DOI: 10.1016/s0021-9258(18)34135-8.Peer-Reviewed Original ResearchConceptsElectron microscopySubunits of lamininGlobular end regionsBeta subunitLaminin short armsTumor cellsWhole laminin moleculeAlpha subunitSquamous carcinoma cellsHuman squamous carcinoma cellsMicroscopyCell attachmentLaminin moleculeAttachment propertiesCarcinoma cellsTumor cell attachmentBasement membraneLong armAlpha-thrombinAortic endothelial cell migration. I. Matrix requirements and composition.
Madri J, Stenn K. Aortic endothelial cell migration. I. Matrix requirements and composition. American Journal Of Pathology 1982, 106: 180-6. PMID: 7039330, PMCID: PMC1916178.Peer-Reviewed Original Research
1981
Shapes, domain organizations and flexibility of laminin and fibronectin, two multifunctional proteins of the extracellular matrix
Engel J, Odermatt E, Engel A, Madri J, Furthmayr H, Rohde H, Timpl R. Shapes, domain organizations and flexibility of laminin and fibronectin, two multifunctional proteins of the extracellular matrix. Journal Of Molecular Biology 1981, 150: 97-120. PMID: 6795355, DOI: 10.1016/0022-2836(81)90326-0.Peer-Reviewed Original ResearchRole of basal lamina in neoplastic disorganization of tissue architecture.
Ingber D, Madri J, Jamieson J. Role of basal lamina in neoplastic disorganization of tissue architecture. Proceedings Of The National Academy Of Sciences Of The United States Of America 1981, 78: 3901-3905. PMID: 7022458, PMCID: PMC319681, DOI: 10.1073/pnas.78.6.3901.Peer-Reviewed Original Research
1980
Ultrastructural localization of fibronectin and laminin in the basement membranes of the murine kidney.
Madri J, Roll F, Furthmayr H, Foidart J. Ultrastructural localization of fibronectin and laminin in the basement membranes of the murine kidney. Journal Of Cell Biology 1980, 86: 682-687. PMID: 6995470, PMCID: PMC2111490, DOI: 10.1083/jcb.86.2.682.Peer-Reviewed Original ResearchConceptsTubular basement membraneMesangial areaBowman's capsuleMesangial matrixBasement membraneFrozen sectionsNormal murine kidneyMurine kidneyAffinity-purified rabbit antibodiesConventional frozen sectionsGlomerular basement membraneSheep anti-rabbit IgGLaminin labellingThick frozen sectionsImmunofluorescence stainingSpecific antibodiesRabbit antibodiesLamina rara internaMesangial cell processesKidneyUltrastructural levelCapsuleAntibodiesAnti-rabbit IgGLaminin