2010
Myometrial Wound Healing Post-Cesarean Delivery in the MRL/MpJ Mouse Model of Uterine Scarring
Buhimschi CS, Zhao G, Sora N, Madri JA, Buhimschi IA. Myometrial Wound Healing Post-Cesarean Delivery in the MRL/MpJ Mouse Model of Uterine Scarring. American Journal Of Pathology 2010, 177: 197-207. PMID: 20489145, PMCID: PMC2893663, DOI: 10.2353/ajpath.2010.091209.Peer-Reviewed Original ResearchConceptsCesarean deliveryStrains of miceMRL strainSignificant differencesPost-cesarean deliveryTissue 3 daysUterine scarringMRL/Uterine scarUterine healingWound healing characteristicsMRL miceHistological indicesMouse modelDay 3Day 15Day 60Wall repairMiceMitotic activityWound repairBiomechanical parametersHealing characteristicsMyometriumBiomechanical properties
1992
Independent modulation of enterocyte migration and proliferation by growth factors, matrix proteins, and pharmacologic agents in an in vitro model of mucosal healing.
Basson M, Modlin I, Flynn S, Jena B, Madri J. Independent modulation of enterocyte migration and proliferation by growth factors, matrix proteins, and pharmacologic agents in an in vitro model of mucosal healing. Surgery 1992, 112: 299-307; discussion 307-8. PMID: 1353641.Peer-Reviewed Original ResearchConceptsMucosal healingPharmacologic agentsGrowth factorEGF-stimulated proliferationCaco-2 enterocytesHuman Caco-2 enterocytesInhibited basalAlpha 2 integrin subunitMatrix proteinsEnterocyte migrationCollagen IInhibitor genisteinIntegrin subunitsHealingIndomethacinProliferationTyrosine kinaseEGFLamininBasalGenisteinAltered organizationIndependent modulationCollagens facilitate epithelial migration in restitution of native guinea pig intestinal epithelium
Moore R, Madri J, Carlson S, Madara J. Collagens facilitate epithelial migration in restitution of native guinea pig intestinal epithelium. Gastroenterology 1992, 102: 119-130. PMID: 1727745, DOI: 10.1016/0016-5085(92)91791-2.Peer-Reviewed Original Research
1991
Effects of soluble factors and extracellular matrix components on vascular cell behavior in vitro and in vivo: Models of de‐endothelialization and repair
Madri J, Marx M, Merwin J, Basson C, Prinz C, Bell L. Effects of soluble factors and extracellular matrix components on vascular cell behavior in vitro and in vivo: Models of de‐endothelialization and repair. Journal Of Cellular Biochemistry 1991, 45: 123-130. PMID: 1711525, DOI: 10.1002/jcb.240450202.Peer-Reviewed Original ResearchConceptsSoluble factorsEndothelial cellsVascular smooth muscle cellsCell populationsSite of injuryMicrovascular endothelial cellsSmooth muscle cellsVessel endothelial cellsEndothelial vascular cellsLarge vessel endothelial cellsVascular cell populationsCell typesIntimal thickeningDenudation injuryVascular cell typesArterial mediaSubsequent lumen formationDifferent cell populationsInjuryCell responsesMuscle cellsVascular cellsExtracellular matrixSoft tissueVascular cell behavior