The induction of 72-kD gelatinase in T cells upon adhesion to endothelial cells is VCAM-1 dependent.
Romanic A, Madri J. The induction of 72-kD gelatinase in T cells upon adhesion to endothelial cells is VCAM-1 dependent. Journal Of Cell Biology 1994, 125: 1165-1178. PMID: 7515069, PMCID: PMC2120055, DOI: 10.1083/jcb.125.5.1165.Peer-Reviewed Original ResearchConceptsVascular cell adhesion molecule-1Recombinant VCAM-1T cellsT cell transmigrationEndothelial cellsNegative endothelial cellsCell transmigrationCell adhesion molecule-1Transmigrated T cellsExperimental autoimmune encephalomyelitisT cell extravasationAdhesion molecule-1Late antigen-4VCAM-1 positive cellsMyelin basic proteinAutoimmune encephalomyelitisEndothelial cell monolayersAntigen-4Brain parenchymaNormal miceEndothelial cell layerPositive cellsMolecule-1Perivascular tissueT cell adhesion