Autocrine angiotensin system regulation of bovine aortic endothelial cell migration and plasminogen activator involves modulation of proto-oncogene pp60c-src expression.
Bell L, Luthringer D, Madri J, Warren S. Autocrine angiotensin system regulation of bovine aortic endothelial cell migration and plasminogen activator involves modulation of proto-oncogene pp60c-src expression. Journal Of Clinical Investigation 1992, 89: 315-320. PMID: 1370299, PMCID: PMC442850, DOI: 10.1172/jci115578.Peer-Reviewed Original ResearchMeSH Keywords1-Sarcosine-8-Isoleucine Angiotensin IIAngiotensin IIAngiotensin Receptor AntagonistsAngiotensin-Converting Enzyme InhibitorsAnimalsAortaCattleCell MovementCells, CulturedEnalaprilEndothelium, VascularGene Expression Regulation, ViralLisinoprilPlasminogen ActivatorsProtein KinasesProto-Oncogene Proteins pp60(c-src)Receptors, AngiotensinRNA, MessengerConceptsEndothelial cell migrationC-Src expressionCell migrationC-SrcProto-oncogene c-srcC-Src kinase activityPp60c-src expressionCoding sequenceKinase activityU-PABovine aortic endothelial cell migrationAngiotensin-converting enzyme inhibitor lisinoprilRetroviral vectorsProtein 3Plasminogen activatorStable infectionExpressionDenudation injuryPlasminogen activator activityActivatorActivity 2Cell expressionAngiotensin system inhibitionActivator activityEndothelial cell expression