1999
Hyperglycemia-Induced Vasculopathy in the Murine Vitelline Vasculature Correlation with PECAM-1/CD31 Tyrosine Phosphorylation State
Pinter E, Mahooti S, Wang Y, Imhof B, Madri J. Hyperglycemia-Induced Vasculopathy in the Murine Vitelline Vasculature Correlation with PECAM-1/CD31 Tyrosine Phosphorylation State. American Journal Of Pathology 1999, 154: 1367-1379. PMID: 10329590, PMCID: PMC1866605, DOI: 10.1016/s0002-9440(10)65391-6.Peer-Reviewed Original ResearchConceptsPECAM-1 tyrosine phosphorylationTyrosine phosphorylation stateMurine conceptusYolk sacCell-extracellular matrixFirst organ systemCell-factor interactionsTyrosine dephosphorylationEndothelial cell migrationEmbryonic angioblastsEmbryonic developmentMesodermal cellsVasculogenesis/angiogenesisTyrosine phosphorylationPhosphorylation statePerinatal lethalityNormal organogenesisVascular systemCell migrationHematopoietic cellsDiabetic pregnant miceComplex vascular systemVasculogenesisPECAM-1 expressionOffspring
1998
Platelet endothelial cell adhesion molecule-1 expression modulates endothelial cell migration in vitro.
Kim C, Wang T, Madri J. Platelet endothelial cell adhesion molecule-1 expression modulates endothelial cell migration in vitro. Laboratory Investigation 1998, 78: 583-90. PMID: 9605183.Peer-Reviewed Original ResearchConceptsWild-type PECAM-1Endothelial cell migrationEndogenous PECAM-1Cell migrationCell-extracellular matrix interactionsMatrix interactionsTyrosine phosphorylation stateMurine conceptusCell-cell adhesionC-myc epitopeIntegrin-extracellular matrix interactionsCell-cell interactionsPECAM-1Endothelial cellsDynamic dephosphorylationCytoskeletal reorganizationEmbryonic vasculogenesisPhosphorylation stateMigratory stateMigration rateRetroviral transductionCultured endothelial cellsEndothelial cell adhesion molecule-1 expressionEndothelial cell adhesion molecule-1Y686