2008
Engineering angiogenesis following spinal cord injury: a coculture of neural progenitor and endothelial cells in a degradable polymer implant leads to an increase in vessel density and formation of the blood–spinal cord barrier
Rauch MF, Hynes SR, Bertram J, Redmond A, Robinson R, Williams C, Xu H, Madri JA, Lavik EB. Engineering angiogenesis following spinal cord injury: a coculture of neural progenitor and endothelial cells in a degradable polymer implant leads to an increase in vessel density and formation of the blood–spinal cord barrier. European Journal Of Neuroscience 2008, 29: 132-145. PMID: 19120441, PMCID: PMC2764251, DOI: 10.1111/j.1460-9568.2008.06567.x.Peer-Reviewed Original ResearchMeSH KeywordsAbsorbable ImplantsAnimalsBlood VesselsBlood-Brain BarrierCells, CulturedCoculture TechniquesDisease Models, AnimalEndothelial CellsFemaleGlycolatesHydrogelsLactic AcidMicrocirculationNeovascularization, PhysiologicPolyglycolic AcidPolylactic Acid-Polyglycolic Acid CopolymerRatsRats, Sprague-DawleyRats, TransgenicSpinal CordSpinal Cord InjuriesStem Cell TransplantationTissue EngineeringTissue ScaffoldsTreatment OutcomeConceptsBlood-spinal cord barrierSpinal cord injuryCord injuryNeural progenitor cellsEndothelial cellsPositive stainingRat hemisection modelEndothelial barrier antigenFunctional vesselsRole of angiogenesisInjury epicenterSimilar coculturesSpinal cordNPC groupHemisection modelEC groupVessel densityLesion controlInjuryNeural regenerationProgenitor cellsAngiogenesisNeural progenitorsSubcutaneous modelCoculture
2006
Wobbly Hedgehog Syndrome in African Pygmy Hedgehogs (Atelerix spp.)
Graesser D, Spraker T, Dressen P, Garner M, Raymond J, Terwilliger G, Kim J, Madri J. Wobbly Hedgehog Syndrome in African Pygmy Hedgehogs (Atelerix spp.). Journal Of Exotic Pet Medicine 2006, 15: 59-65. DOI: 10.1053/j.jepm.2005.11.010.Peer-Reviewed Original ResearchWobbly hedgehog syndromeCentral nervous systemClinical signsNervous systemNeurogenic muscle atrophySevere neurologic signsYears of agePost-mortem examinationAfrican pygmy hedgehogNeurologic signsSpinal cordProgression rateMuscle atrophyProgressive paralysisCharacteristic histopathologyComplete paralysisMild ataxiaFamilial tendencyWhite matterAfrican hedgehogSyndromeParalysisSignsAgeOnset