1993
Functional CD4 T cell subset interplay in an intact immune system.
Murray J, Madri J, Pasqualini T, Bottomly K. Functional CD4 T cell subset interplay in an intact immune system. The Journal Of Immunology 1993, 150: 4270-6. PMID: 8097751, DOI: 10.4049/jimmunol.150.10.4270.Peer-Reviewed Original ResearchConceptsCD4 T cellsTh-2 cellsT cellsIL-5Antibody formationIFN-gammaTh-2-like cellsF1 hybrid T cellsIntact immune systemTh-1 cellsGood proliferative responsesCollagen IVCell primingProliferative responseImmune systemTh-1Hybrid miceMiceGamma treatmentAdditional studiesHuman collagen IVImmunizationSelective activationVivoCells
1989
MHC control of CD4+ T cell subset activation.
Murray J, Madri J, Tite J, Carding S, Bottomly K. MHC control of CD4+ T cell subset activation. Journal Of Experimental Medicine 1989, 170: 2135-2140. PMID: 2573684, PMCID: PMC2189542, DOI: 10.1084/jem.170.6.2135.Peer-Reviewed Original ResearchConceptsT cellsIL-2IL-4-producing CD4T cell subset activationIL-4-producing cellsI-Ab miceMHC class II haplotypesCytokine-producing CD4T-cell phenotypeTypes of CD4Secondary IgG responsesClass II MHCSelective activationClass II haplotypesMHC controlSuch selective activationCytokine phenotypeIgG responsesSubset activationII MHCImmune responseProliferative responseCD4Vivo responseMice