Inverse Ir gene control of the antibody and T cell proliferative responses to human basement membrane collagen.
Tite J, Foellmer H, Madri J, Janeway C. Inverse Ir gene control of the antibody and T cell proliferative responses to human basement membrane collagen. The Journal Of Immunology 1987, 139: 2892-8. PMID: 3117879, DOI: 10.4049/jimmunol.139.9.2892.Peer-Reviewed Original ResearchConceptsT cell proliferative responsesCell proliferative responsesAntibody responseIr gene controlProliferative responseT cellsHigher antibody responseClass II MHCMHC congenic miceMajor histocompatibility complexImmunologic responsivenessResponder parentF1 miceII MHCDifferent MHC genotypesImmune responseType IV collagenCongenic miceMiceHistocompatibility complexIV collagenDifferential activationAntigenBasement membrane collagenMHC genotype