Bronchial Lavage Proteins as Correlates of Histopathologic Airway Changes in Healthy Smokers and Patients with Pulmonary Carcinoma1–4
Merrill W, Barwick K, Madri J, Strober W, Matthay R, Olchowski J, Naegel G, Reynolds H. Bronchial Lavage Proteins as Correlates of Histopathologic Airway Changes in Healthy Smokers and Patients with Pulmonary Carcinoma1–4. American Journal Of Respiratory And Critical Care Medicine 1984, 130: 905-9. PMID: 6208835, DOI: 10.1164/arrd.1984.130.5.905.Peer-Reviewed Original ResearchConceptsFree secretory componentSymptomatic smokersCarcinoma patientsAsymptomatic smokersLavage fluidLung diseaseCancer patientsSmoking-associated lung diseasePacks/yearHigh-risk subgroupsImportant etiologic factorNumber of smokersAirway changesAirway injuryGroups of subjectsHealthy smokersSmoking historyNormal nonsmokersLavage levelsCigarette smokingSmoking populationEtiologic factorsLavage proteinImmunohistochemical evidenceLung sections