Human enterocyte (Caco-2) migration is modulated in vitro by extracellular matrix composition and epidermal growth factor.
Basson M, Modlin I, Madri J. Human enterocyte (Caco-2) migration is modulated in vitro by extracellular matrix composition and epidermal growth factor. Journal Of Clinical Investigation 1992, 90: 15-23. PMID: 1634605, PMCID: PMC443057, DOI: 10.1172/jci115828.Peer-Reviewed Original ResearchConceptsEpidermal growth factorCaco-2 cellsGrowth factorEGF treatmentEnterocyte migrationHuman colonic cell lineColonic cell lineAlpha 2 subunitIntegrin surface expressionEGF-treated cellsAlpha integrin subunitsCollagen I.Functional antibodiesCell surface receptorsCollagen type IIntegrin expressionAlpha 2Basal migrationCell proliferationSurface expressionCollagen IExtracellular matrix compositionCell linesIntegrin subunitsSurface receptors