2021
Pain intensity and pain medication prescription patterns in Veterans with heart failure and back pain
Cavanagh CE, Rosman L, Chui PW, DeRycke E, Bathulapalli H, Gandhi P, Bastian LA, Burg MM, Brandt C, Goulet JL. Pain intensity and pain medication prescription patterns in Veterans with heart failure and back pain. Heart & Lung 2021, 50: 770-774. PMID: 34225088, DOI: 10.1016/j.hrtlng.2021.04.016.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAnalgesics, OpioidBack PainHeart FailureHumansMiddle AgedPain MeasurementPrescriptionsVeteransConceptsComorbid heart failureHeart failureBack painPain intensityMedication prescription patternsPain medication prescriptionsHigher likelihoodGabapentin prescriptionsNSAID prescriptionsPrescription patternsSevere painPain conditionsMedication prescriptionsClinical managementPainMusculoskeletal disordersDisorder cohortLower likelihoodVeteransFurther studiesPrescriptionFailureOpioidsCardiovascularCohort
2018
Patterns of Alcohol Use Among Patients Living With HIV in Urban, Large Rural, and Small Rural Areas
Bensley KM, McGinnis KA, Fortney J, Chan KCG, Dombrowski JC, Ornelas I, Edelman EJ, Goulet JL, Satre DD, Justice AC, Fiellin DA, Williams EC. Patterns of Alcohol Use Among Patients Living With HIV in Urban, Large Rural, and Small Rural Areas. The Journal Of Rural Health 2018, 35: 330-340. PMID: 30339740, PMCID: PMC6502702, DOI: 10.1111/jrh.12326.Peer-Reviewed Original ResearchConceptsSmall rural areasAlcohol useAUDIT-C alcoholElectronic health record dataHealth record dataAlcohol-related interventionsPrevalence of AUDAlcohol use outcomesHeavy episodic drinkingPLWHRural areasReporting useHIVUse outcomesRecord dataEpisodic drinkingPatientsPrevalenceRegression modelsDrinkingRuralityAUDUnique challengesEvaluation of Complementary and Integrative Health Approaches Among US Veterans with Musculoskeletal Pain Using Propensity Score Methods
Han L, Goulet JL, Skanderson M, Bathulapalli H, Luther SL, Kerns RD, Brandt CA. Evaluation of Complementary and Integrative Health Approaches Among US Veterans with Musculoskeletal Pain Using Propensity Score Methods. Pain Medicine 2018, 20: 90-102. PMID: 29584926, PMCID: PMC6329442, DOI: 10.1093/pm/pny027.Peer-Reviewed Original ResearchConceptsIntegrative health approachesPS matchingCIH exposureMusculoskeletal painPropensity score methodsSelf-rated pain intensityHealth approachHigher pain intensity ratingsPain intensity outcomesChronic musculoskeletal painPain intensity ratingsIPTW modelsRetrospective cohortPain intensityChronic painClinical visitsInitial diagnosisChiropractic careUS veteransBaseline differencesTreatment weightingExposure groupPainScore methodTreatment effectiveness
2017
Discontinuing a non-steroidal anti-inflammatory drug (NSAID) in patients with knee osteoarthritis: Design and protocol of a placebo-controlled, noninferiority, randomized withdrawal trial
Goulet JL, Buta E, Brennan M, Heapy A, Fraenkel L. Discontinuing a non-steroidal anti-inflammatory drug (NSAID) in patients with knee osteoarthritis: Design and protocol of a placebo-controlled, noninferiority, randomized withdrawal trial. Contemporary Clinical Trials 2017, 65: 1-7. PMID: 29198731, DOI: 10.1016/j.cct.2017.11.020.Peer-Reviewed Original ResearchMeSH KeywordsAcetaminophenAdultAge FactorsAgedAged, 80 and overAnti-Inflammatory Agents, Non-SteroidalDisability EvaluationDouble-Blind MethodEquivalence Trials as TopicFemaleHumansMaleMeloxicamMiddle AgedOsteoarthritis, KneePain MeasurementPatient Education as TopicResearch DesignSeverity of Illness IndexSex FactorsSocial SupportYoung AdultConceptsNon-steroidal anti-inflammatory drugsUse of NSAIDsOA knee painKnee painKnee osteoarthritisAnti-inflammatory drugsWithdrawal trialCurrent non-steroidal anti-inflammatory drugsKnee OA painPainful knee osteoarthritisClasses of medicationsLower extremity disabilityTwo-week runFirst clinical trialVA healthcare systemOA painEligible subjectsSecondary outcomesPrimary outcomeGlobal ImpressionNSAID toxicityNoninferiority marginClinical trialsExtremity disabilityCommon causeMultiple Sources of Prescription Payment and Risky Opioid Therapy Among Veterans
Becker WC, Fenton BT, Brandt CA, Doyle EL, Francis J, Goulet JL, Moore BA, Torrise V, Kerns RD, Kreiner PW. Multiple Sources of Prescription Payment and Risky Opioid Therapy Among Veterans. Medical Care 2017, 55: s33-s36. PMID: 28410338, DOI: 10.1097/mlr.0000000000000722.Peer-Reviewed Original ResearchConceptsOpioid therapySource of paymentHigher oddsHigh-dose opioid therapyHigh-risk opioid prescribingMorphine equivalent daily dosePayment sourceOpioid analgesic prescriptionsPrescription monitoring programsEquivalent daily doseCross-sectional studyAnalgesic prescriptionOpioid prescribingBenzodiazepine therapyDaily doseUS veteransFiscal year 2014TherapyPrivate insuranceLogistic regressionRelated harmsPrescription paymentAnalytic sampleOpioidsOdds
2016
Estimating healthcare mobility in the Veterans Affairs Healthcare System
Wang KH, Goulet JL, Carroll CM, Skanderson M, Fodeh S, Erdos J, Womack JA, Abel EA, Bathulapalli H, Justice AC, Nunez-Smith M, Brandt CA. Estimating healthcare mobility in the Veterans Affairs Healthcare System. BMC Health Services Research 2016, 16: 609. PMID: 27769221, PMCID: PMC5075153, DOI: 10.1186/s12913-016-1841-4.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overDelivery of Health CareElectronic Health RecordsEmigration and ImmigrationFemaleHospitals, VeteransHumansMaleMental DisordersMiddle AgedPatient Acceptance of Health CareRetrospective StudiesUnited StatesUnited States Department of Veterans AffairsVeteransVeterans HealthYoung AdultConceptsHealthcare systemVeterans Health Administration electronic health recordsVeterans Affairs Healthcare SystemHealthcare mobilityRetrospective cohort studyHepatitis C virusOutcomes of careDifferent healthcare systemsDistinct healthcare systemsElectronic health recordsClinical characteristicsCohort studyHealthcare utilizationC virusSpecialty carePsychiatric disordersYounger veteransDisease preventionYounger agePopulation healthHealth recordsVeteransStatus changesCareYear periodThe musculoskeletal diagnosis cohort
Goulet JL, Kerns RD, Bair M, Becker W, Brennan P, Burgess DJ, Carroll CM, Dobscha S, Driscoll M, Fenton BT, Fraenkel L, Haskell S, Heapy A, Higgins D, Hoff RA, Hwang U, Justice AC, Piette JD, Sinnott P, Wandner L, Womack J, Brandt CA. The musculoskeletal diagnosis cohort. Pain 2016, 157: 1696-1703. PMID: 27023420, PMCID: PMC4949131, DOI: 10.1097/j.pain.0000000000000567.Peer-Reviewed Original ResearchConceptsMSD diagnosisMusculoskeletal disordersMSD cohortIndex dateVeterans Health Administration (VHA) careNumeric rating scale scoreICD-9-CM codesCohort inclusion criteriaNontraumatic joint disordersPain-related treatmentsMore outpatient visitsVeterans Health AdministrationMental health diagnosesRating Scale scoresHigher NRS scoresHealth services researchElectronic health recordsDiagnosis cohortSevere painInpatient visitsNRS scoresOutpatient visitsNeck disordersFirst diagnosisMean age
2014
A Partnered Approach to Opioid Management, Guideline Concordant Care and the Stepped Care Model of Pain Management
Dorflinger L, Moore B, Goulet J, Becker W, Heapy AA, Sellinger JJ, Kerns RD. A Partnered Approach to Opioid Management, Guideline Concordant Care and the Stepped Care Model of Pain Management. Journal Of General Internal Medicine 2014, 29: 870-876. PMID: 25355083, PMCID: PMC4239281, DOI: 10.1007/s11606-014-3019-2.Peer-Reviewed Original ResearchConceptsLong-term opioid therapyOpioid risk mitigation strategiesOpioid therapyGuideline-concordant careVeterans Health AdministrationPain managementStepped care modelOpioid managementChronic painPain carePrimary carePractice guidelinesCare modelHigh-dose opioidsKey ResultsThe proportionProportion of patientsNon-opioid analgesicsClinical practice guidelinesCommon presenting problemManagement of veteransPerformance improvement outcomesClinical research teamInteractive educational strategiesFour-year study periodConcordant care
2012
HIV as an independent risk factor for incident lung cancer
Sigel K, Wisnivesky J, Gordon K, Dubrow R, Justice A, Brown ST, Goulet J, Butt AA, Crystal S, Rimland D, Rodriguez-Barradas M, Gibert C, Park LS, Crothers K. HIV as an independent risk factor for incident lung cancer. AIDS 2012, 26: 1017-1025. PMID: 22382152, PMCID: PMC3580210, DOI: 10.1097/qad.0b013e328352d1ad.Peer-Reviewed Original ResearchConceptsIncidence rate ratiosIndependent risk factorUninfected patientsLung cancerSimilar HIVHIV infectionSurveillance biasRisk factorsIncidence rateVeterans Aging Cohort Study Virtual CohortVeterans Affairs Central Cancer RegistryChronic obstructive pulmonary diseaseIncident lung cancerObstructive pulmonary diseaseCentral Cancer RegistryLung cancer stageSimilar stage distributionRace/ethnicityExcess smokingMultivariable adjustmentAnalytic cohortPulmonary diseaseBacterial pneumoniaCancer RegistryPotential confounders
2011
Alcohol consumption and depressive symptoms over time: A longitudinal study of patients with and without HIV infection
Sullivan LE, Goulet JL, Justice AC, Fiellin DA. Alcohol consumption and depressive symptoms over time: A longitudinal study of patients with and without HIV infection. Drug And Alcohol Dependence 2011, 117: 158-163. PMID: 21345624, PMCID: PMC3113463, DOI: 10.1016/j.drugalcdep.2011.01.014.Peer-Reviewed Original ResearchConceptsVeterans Aging Cohort StudyNon-hazardous drinkersDepressive symptomsAlcohol consumptionAlcohol abuseCohort studyHIV infectionBinge drinkersBinge drinkingNon-hazardous drinkingAging Cohort StudyPatient Health QuestionnaireUnhealthy alcohol consumptionCurrent alcohol useHIV statusHealth QuestionnaireTime-varying outcomeHazardous drinkersPatientsHIVHazardous drinkingAlcohol dependenceSymptomsAlcohol useSimilar alterationsIncreased Risk of Fragility Fractures among HIV Infected Compared to Uninfected Male Veterans
Womack JA, Goulet JL, Gibert C, Brandt C, Chang CC, Gulanski B, Fraenkel L, Mattocks K, Rimland D, Rodriguez-Barradas MC, Tate J, Yin MT, Justice AC, . Increased Risk of Fragility Fractures among HIV Infected Compared to Uninfected Male Veterans. PLOS ONE 2011, 6: e17217. PMID: 21359191, PMCID: PMC3040233, DOI: 10.1371/journal.pone.0017217.Peer-Reviewed Original ResearchConceptsBody mass indexHIV infectionUninfected menFragility fracturesFracture riskRisk factorsMale veteransVeterans Aging Cohort Study Virtual CohortCurrent protease inhibitor useFragility fracture risk factorsMedian body mass indexHIV-specific factorsAdjusted hazard ratioProtease inhibitor useFracture risk factorsFragility fracture riskIncident hipHazard ratioInhibitor useUnadjusted riskHIV statusMass indexAlcohol abuseHIVUpper armGlycemic Control and Infections in Patients with Diabetes Undergoing Noncardiac Surgery
King JT, Goulet JL, Perkal MF, Rosenthal RA. Glycemic Control and Infections in Patients with Diabetes Undergoing Noncardiac Surgery. Annals Of Surgery 2011, 253: 158-165. PMID: 21135698, DOI: 10.1097/sla.0b013e3181f9bb3a.Peer-Reviewed Original ResearchConceptsSerum glucose concentrationPerioperative glucose controlPostoperative infectionGlucose controlSurgical proceduresDiabetic patientsGlucose concentrationNational Surgical Quality Improvement Program databaseInfection rateOverall postoperative infection rateQuality Improvement Program databaseMultivariate Poisson regression modelNoncardiac surgical proceduresPostoperative infectious complicationsImprovement Program databasePostoperative infection rateSurgical outcome dataNationwide samplePoisson regression modelsPreoperative HbA1cPreoperative laboratoryInfectious complicationsNoncardiac surgeryNoncardiac operationsGlycemic control
2010
Patterns of drug use and abuse among aging adults with and without HIV: A latent class analysis of a US Veteran cohort
Green TC, Kershaw T, Lin H, Heimer R, Goulet JL, Kraemer KL, Gordon AJ, Maisto SA, Day NL, Bryant K, Fiellin DA, Justice AC. Patterns of drug use and abuse among aging adults with and without HIV: A latent class analysis of a US Veteran cohort. Drug And Alcohol Dependence 2010, 110: 208-220. PMID: 20395074, PMCID: PMC3087206, DOI: 10.1016/j.drugalcdep.2010.02.020.Peer-Reviewed Original ResearchConceptsVeterans Aging Cohort StudyHIV statusMultidrug usersDrug useLatent class analysisUS Veteran cohortAging Cohort StudyActive drug useSelf-reported drug useMental health disordersProblem of obesityElectronic medical recordsUninfected veteransCohort studyClinical variablesDrug use consequencesSocio-demographic covariatesMedical recordsHigh prevalenceUninfected adultsAge 50HIVHealth disordersDrug usersVeteran cohortPsychosocial distress in patients treated for cancer pain: a prospective observational study.
O'Mahony S, Goulet JL, Payne R. Psychosocial distress in patients treated for cancer pain: a prospective observational study. Journal Of Opioid Management 2010, 6: 211-22. PMID: 20642250, DOI: 10.5055/jom.2010.0019.Peer-Reviewed Original Research
2005
Relative prevalence of comorbidities and treatment contraindications in HIV-mono-infected and HIV/HCV-co-infected veterans
Goulet JL, Fultz SL, McGinnis KA, Justice AC. Relative prevalence of comorbidities and treatment contraindications in HIV-mono-infected and HIV/HCV-co-infected veterans. AIDS 2005, 19: s99-s105. PMID: 16251836, DOI: 10.1097/01.aids.0000192077.11067.e5.Peer-Reviewed Original ResearchConceptsHIV/HCV-coHepatitis C virusAlcohol-related complicationsComorbid conditionsHCV-coTreatment optionsHIV monoChart extractionDiagnostic codesMental disordersCo-infected patientsElectronic medical record systemTreatment contraindicationsMedical record systemC virusHigh prevalenceMedical disordersHIVDemographic dataComorbiditiesLogistic regressionPrevalenceModerate agreementRelative prevalenceVeterans