Familial Transmission of Substance Use Disorders
Merikangas KR, Stolar M, Stevens DE, Goulet J, Preisig MA, Fenton B, Zhang H, O'Malley SS, Rounsaville BJ. Familial Transmission of Substance Use Disorders. JAMA Psychiatry 1998, 55: 973-979. PMID: 9819065, DOI: 10.1001/archpsyc.55.11.973.Peer-Reviewed Original ResearchConceptsSubstance use disordersAdult first-degree relativesFirst-degree relativesDrug disordersRisk factorsUse disordersPredominant drugFamilial aggregationPotent risk factorRelatives of probandsAntisocial personality disorderFamily history interviewSubstance disordersFamily historyControl probandsDiagnostic InterviewOpioidsPersonality disorderDisordersFamilial transmissionGenetic factorsProbandsCocaineDrugsCannabis