2018
Cell-Based Immunotherapy of Gliomas
Everson R, Antonios J, Liau L. Cell-Based Immunotherapy of Gliomas. Progress In Neurological Surgery 2018, 32: 90-100. PMID: 29990977, DOI: 10.1159/000469683.Peer-Reviewed Original ResearchConceptsCellular immunotherapyImmune cellsDendritic cell (DC)-based vaccinesTreatment of malignant gliomasCellular immunotherapy approachesAntitumor immune cellsAntitumor responseAdoptive transferImmunotherapy approachesActive immunotherapyLive immune cellsMalignant gliomasEffector capabilitiesPassive immunotherapyImmunotherapyImmune responseEx vivoImmune systemGlioma cellsCell typesPatientsGliomaCellsNeoplasms
2017
Chapter 12 Dendritic Cell Therapy for Brain Tumors
Everson R, Antonios J, Tucker A, Liau L. Chapter 12 Dendritic Cell Therapy for Brain Tumors. 2017, 301-321. DOI: 10.1016/b978-0-12-802420-1.00012-0.Peer-Reviewed Original ResearchDC therapyDendritic cellsClinical trialsEvidence of immune responsesImmune responseLimitations of current treatment optionsTreatment of malignant gliomasDendritic cell therapyAntitumor immune responseAntigen presenting abilityCurrent treatment optionsDevelopment of alternative modalitiesDC vaccinesActive immunotherapyProlonged survivalMalignant gliomasPreclinical modelsTreatment optionsTumor cellsCell therapyClinical effectsVaccine formulationsBrain tumorsImmune systemBrain parenchyma
2014
Chronic inflammation drives glioma growth: cellular and molecular factors responsible for an immunosuppressive microenvironment
Ha E, Antonios J, Soto H, Prins R, Yang I, Kasahara N, Liau L, Kruse C. Chronic inflammation drives glioma growth: cellular and molecular factors responsible for an immunosuppressive microenvironment. Neuroimmunology And Neuroinflammation 2014, 1: 66-76. DOI: 10.4103/2347-8659.139717.Peer-Reviewed Original ResearchImmunosuppressive microenvironmentTumor massPatient's own immune systemGrade of malignancyCell typesCharacteristics of gliomasTumor microenvironmentGene therapyInflammatory microenvironmentChronic inflammationGlioma patientsImmune systemGliomaGlioma growthDisease initiationMicroenvironmentTumorMolecular factorsPatientsCellsMalignancyTherapyInflammationClearanceImmune-