2003
Intracellular Chloride Accumulation and Subcellular Elemental Distribution During Atrial Fibrillation
Akar JG, Everett TH, Ho R, Craft J, Haines DE, Somlyo AP, Somlyo AV. Intracellular Chloride Accumulation and Subcellular Elemental Distribution During Atrial Fibrillation. Circulation 2003, 107: 1810-1815. PMID: 12665494, DOI: 10.1161/01.cir.0000058462.23347.93.Peer-Reviewed Original ResearchConceptsEffective refractory periodLeft atrial appendageAtrial fibrillationMitochondrial Ca overloadWhole-cell ClWhole-cell NaIntracellular chloride accumulationIntracellular Cl- accumulationSinus rhythmAtrial appendageCa overloadElectrical remodelingAF pathogenesisRapid pacingRefractory periodTransient increaseTransverse cryosectionsMembrane depolarizationFibrillationNovel findingsCytosolic CaCytoplasmic CaConcomitant increaseIon channelsMinutesEffect of Heating on Pulmonary Veins:
KOK LC, EVERETT TH, AKAR JG, HAINES DE. Effect of Heating on Pulmonary Veins:. Journal Of Cardiovascular Electrophysiology 2003, 14: 250-254. PMID: 12716105, DOI: 10.1046/j.1540-8167.2003.02490.x.Peer-Reviewed Original ResearchConceptsRadiofrequency energy catheter ablationHyperthermic exposurePulmonary vein stenosisChronic atrial fibrillationTreatment of patientsLoss of complianceHeat-induced contractionHeat exposurePV stenosisVein stenosisCatheter ablationAtrial fibrillationPulmonary veinsLeft atriumAcute effectsMain PVCanine heartPV specimensMean circumferenceDegrees CStenosisExposureBaselineCircumferenceCollagen matrix
2002
Use of global atrial fibrillation organization to optimize the success of burst pace termination
Everett TH, Akar JG, Kok LC, Moorman JR, Haines DE. Use of global atrial fibrillation organization to optimize the success of burst pace termination. Journal Of The American College Of Cardiology 2002, 40: 1831-1840. PMID: 12446068, DOI: 10.1016/s0735-1097(02)02476-2.Peer-Reviewed Original ResearchConceptsAtrial fibrillationRight atriumPace terminationBiatrial pacingAtrial conduction blockSuccess rateBipolar atrial electrogramOverall success rateOrganization indexAtrial pacingDecapolar catheterConduction blockAtrial electrogramsBurst terminationElectrogram recordingsPacingHigh efficacyAtrial fibrillation organizationFibrillationEffect of Electrical and Structural Remodeling on Spatiotemporal Organization in Acute and Persistent Atrial Fibrillation
AKAR JG, EVERETT TH, KOK L, MOORMAN JR, HAINES DE. Effect of Electrical and Structural Remodeling on Spatiotemporal Organization in Acute and Persistent Atrial Fibrillation. Journal Of Cardiovascular Electrophysiology 2002, 13: 1027-1034. PMID: 12435191, DOI: 10.1046/j.1540-8167.2002.01027.x.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAnimalsAtrial FibrillationAtrial FunctionDisease Models, AnimalDogsElectrocardiographyElectrophysiologic Techniques, CardiacEntropyFemaleFollow-Up StudiesHeart AtriaModels, CardiovascularRecovery of FunctionRefractory Period, ElectrophysiologicalSeverity of Illness IndexStatistics as TopicTreatment OutcomeConceptsAtrial effective refractory periodPersistent atrial fibrillationAcute atrial fibrillationAtrial fibrillationStructural remodelingSinus rhythmMean atrial effective refractory periodEffective refractory periodAtrial sizeElectrical remodelingLeft atriumBasket catheterAF dogsIntracardiac echocardiographyAtrial electrogramsRefractory periodRemodelingFibrillationSpatiotemporal organizationRhythmAcuteEchocardiographyCatheterMajor roleRecovery
2001
Assessment of Global Atrial Fibrillation Organization to Optimize Timing of Atrial Defibrillation
Everett T, Moorman J, Kok L, Akar J, Haines D. Assessment of Global Atrial Fibrillation Organization to Optimize Timing of Atrial Defibrillation. Circulation 2001, 103: 2857-2861. PMID: 11401945, DOI: 10.1161/01.cir.103.23.2857.Peer-Reviewed Original Research