Presence of asymmetric dimethylarginine gradients across high-grade lesions in patients with coronary artery disease
Joyal D, Leya F, Al-Chekakie M, Arab D, Dieter RS, Morshedi-Meibodi A, Lewis B, Steen L, Fareed J, Hoppenstead D, Akar JG. Presence of asymmetric dimethylarginine gradients across high-grade lesions in patients with coronary artery disease. Coronary Artery Disease 2007, 18: 471-475. PMID: 17700219, DOI: 10.1097/mca.0b013e32818be79c.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionCoronary interventionCoronary lesionsAsymmetric dimethylarginineEndothelial dysfunctionAsymmetric dimethylarginine accumulationAsymmetric dimethylarginine levelsGeneralized endothelial dysfunctionPeripheral venous siteSystemic venous levelsAsymmetric dimethylarginine concentrationsCoronary artery diseaseHigh-grade lesionsNitric oxide synthaseLevels 24 hDimethylarginine levelsDimethylarginine concentrationsCoronary ostiumArtery diseaseSystemic markersVenous levelsCoronary bedFocal injuryOxide synthaseVenous sites