2023
Predicting Malignant Ventricular Arrhythmias Using Real-Time Remote Monitoring
Ginder C, Li J, Halperin J, Akar J, Martin D, Chattopadhyay I, Upadhyay G. Predicting Malignant Ventricular Arrhythmias Using Real-Time Remote Monitoring. Journal Of The American College Of Cardiology 2023, 81: 949-961. PMID: 36889873, DOI: 10.1016/j.jacc.2022.12.024.Peer-Reviewed Original ResearchConceptsAppropriate device therapyMalignant ventricular arrhythmiasDevice therapyVentricular arrhythmiasImplantable cardioverter-defibrillator therapyLogistic regressionSeparate multivariable logistic regressionsLead impedanceAppropriate ICD therapyCardioverter-defibrillator therapyCardiac resynchronization therapyMultivariable logistic regressionRemote monitoring dataShock lead impedanceAtrial lead impedanceICD therapyHeart failureResynchronization therapyAppropriate therapyAtrial tachyarrhythmiasVentricular tachycardiaVentricular fibrillationDefibrillator devicesHeart ratePatients
2017
Addition of Blood Pressure and Weight Transmissions to Standard Remote Monitoring of Implantable Defibrillators and its Association with Mortality and Rehospitalization
Al-Chekakie MO, Bao H, Jones PW, Stein KM, Marzec L, Varosy PD, Masoudi FA, Curtis JP, Akar JG. Addition of Blood Pressure and Weight Transmissions to Standard Remote Monitoring of Implantable Defibrillators and its Association with Mortality and Rehospitalization. Circulation Cardiovascular Quality And Outcomes 2017, 10: e003087. PMID: 28506978, DOI: 10.1161/circoutcomes.116.003087.Peer-Reviewed Original ResearchConceptsBlood pressure dataImplantable defibrillatorsRemote patient monitoringTransmission of weightHeart failure hospitalizationImpaired ejection fractionCardiac resynchronization therapyCox regression modelRisk of mortalityLogistic regression modelsRoutine weightCause hospitalizationFailure hospitalizationBlood pressureCardiovascular hospitalizationEjection fractionResynchronization therapyRegression modelsDevice implantationService patientsHospital characteristicsIndependent associationImproved outcomesLandmark analysisSimilar risk
2008
Endothelial dysfunction in heart failure identifies responders to cardiac resynchronization therapy
Akar JG, Al-Chekakie MO, Fugate T, Moran L, Froloshki B, Varma N, Santucci P, Wilber DJ, Matsumura ME. Endothelial dysfunction in heart failure identifies responders to cardiac resynchronization therapy. Heart Rhythm 2008, 5: 1229-1235. PMID: 18774094, DOI: 10.1016/j.hrthm.2008.05.027.Peer-Reviewed Original ResearchConceptsCardiac resynchronization therapyFlow-mediated dilationBaseline flow-mediated dilationBaseline endothelial dysfunctionAdditive prognostic valueEndothelial dysfunctionCRT respondersWalk distanceResynchronization therapyPrognostic valueBrachial artery flow-mediated dilationArtery flow-mediated dilationBaseline functional capacityEndothelial function assessmentHeart failure mortalityHeart failure outcomesLikelihood of responseLogistic regression analysisQuality of lifeCurrent selection criteriaEndothelial functionHeart failureQRS durationCurrent guidelinesFunction assessment