2023
In-hospital complications associated with pulmonary vein isolation with adjunctive lesions: the NCDR AFib Ablation Registry
Darden D, Aldaas O, Du C, Munir M, Feld G, Pothineni N, Gopinathannair R, Lakkireddy D, Curtis J, Freeman J, Akar J, Hsu J. In-hospital complications associated with pulmonary vein isolation with adjunctive lesions: the NCDR AFib Ablation Registry. EP Europace 2023, 25: euad124. PMID: 37184436, PMCID: PMC10228609, DOI: 10.1093/europace/euad124.Peer-Reviewed Original ResearchPulmonary vein isolationRisk of complicationsPersistent AFAblation RegistryHospital complicationsVein isolationAdjusted oddsHigher comorbidity burdenAtrial fibrillation ablationCavotricuspid isthmus ablationMultivariable logistic regressionComorbidity burdenMore comorbiditiesAdverse eventsFibrillation ablationIsthmus ablationMajor complicationsCTI ablationHigh heterogeneitySafety outcomesHigh riskComplicationsAblation lesionsLesion typeLesionsInitial Findings From the National Cardiovascular Data Registry of Atrial Fibrillation Ablation Procedures
Hsu J, Darden D, Du C, Marine J, Nichols S, Marcus G, Natale A, Noseworthy P, Selzman K, Varosy P, Masoudi F, Freeman J, Curtis J, Akar J, Kowey P. Initial Findings From the National Cardiovascular Data Registry of Atrial Fibrillation Ablation Procedures. Journal Of The American College Of Cardiology 2023, 81: 867-878. PMID: 36858707, DOI: 10.1016/j.jacc.2022.11.060.Peer-Reviewed Original ResearchConceptsAtrial fibrillation ablation proceduresAblation RegistryHospital outcomesAblation proceduresSuccessful pulmonary vein isolationNational Cardiovascular Data RegistryOutcomes of patientsProspective cohort studyMajority of patientsPulmonary vein isolationEvidence-based guidelinesDifferent patient outcomesReal-world prevalenceProcedural admissionsHospital deathAF ablationCohort studyPericardial effusionVein isolationHeart failureLarge multicenterMajor complicationsCatheter ablationTreatment patternsPatient population
2022
Sex-based differences in atrial fibrillation ablation adverse events
Mszar R, Friedman D, Ong E, Du C, Wang Y, Zeitler E, Cunningham S, Akar J, Curtis J, Freeman J. Sex-based differences in atrial fibrillation ablation adverse events. Heart 2022, 109: 595-605. PMID: 36104219, DOI: 10.1136/heartjnl-2022-321192.Peer-Reviewed Original ResearchConceptsAcute pulmonary vein isolationAdverse eventsPulmonary vein isolationAtrial fibrillationHigh riskSex-based differencesVein isolationCatheter ablationFemale sexLarge prospective registryHospital adverse eventsMajor adverse eventsObservational cohort studyPhrenic nerve damageAF ablation proceduresQuality of lifeAblation RegistryMore comorbiditiesProspective registryAF ablationCohort studyPericardial effusionNerve damagePatient sexVascular injury
2007
The Effects of Statins and Renin‐Angiotensin System Blockers on Atrial Fibrillation Recurrence Following Antral Pulmonary Vein Isolation
CHEKAKIE M, AKAR JG, WANG F, MURADI H, WU J, SANTUCCI P, VARMA N, WILBER DJ. The Effects of Statins and Renin‐Angiotensin System Blockers on Atrial Fibrillation Recurrence Following Antral Pulmonary Vein Isolation. Journal Of Cardiovascular Electrophysiology 2007, 18: 942-946. PMID: 17593228, DOI: 10.1111/j.1540-8167.2007.00887.x.Peer-Reviewed Original ResearchMeSH KeywordsAngiotensin-Converting Enzyme InhibitorsAnti-Arrhythmia AgentsAtrial FibrillationCatheter AblationChemotherapy, AdjuvantDrug CombinationsFemaleHumansHydroxymethylglutaryl-CoA Reductase InhibitorsIllinoisMaleMiddle AgedPrognosisPulmonary VeinsRenin-Angiotensin SystemRisk AssessmentRisk FactorsSecondary PreventionTreatment OutcomeConceptsAngiotensin receptor blockersRenin-angiotensin system blockersAtrial fibrillationEffect of statinsLower AF recurrenceAF recurrenceSystem blockersRecurrence rateRecurrence of AFAntral pulmonary vein isolationAngiotensin system blockersPulmonary vein isolationSubset of patientsCox regression analysisGroup of patientsPersistent atrial fibrillationAnti-inflammatory propertiesMajor treatment optionsRAS blockersReceptor blockersVein isolationConsecutive patientsRetrospective studyTreatment optionsBaseline variables
2005
8. Different Mapping Systems and Approaches for Ablation of Atrial Fibrillation
Wilber D, Lipman E, Madsen H, Lin A, Santucci P, Akar J, Anderson K, Dasari R, Joshi S, Gauri A. 8. Different Mapping Systems and Approaches for Ablation of Atrial Fibrillation. EP Europace 2005, 7: s14-s14. DOI: 10.1016/j.eupc.2005.08.054.Peer-Reviewed Original ResearchAtrial fibrillationCircumferential PV isolationPV isolationLeft atriumAF recurrenceLate recurrenceScar indexHistory of AFGreater LA dimensionLow ejection fractionRecurrent atrial fibrillationPulmonary vein isolationPersistent atrial fibrillationPulmonary vein ostiaLA scarringVein isolationEjection fractionPV ostiaClinical variablesSinus rhythmCircumferential ablationLA dimensionAdditional interventionsNormal controlsMultivariate analysis