2019
Recurrence quantification analysis of complex‐fractionated electrograms differentiates active and passive sites during atrial fibrillation
Baher A, Buck B, Fanarjian M, Mounsey J, Gehi A, Chung E, Akar FG, Webber CL, Akar JG, Hummel JP. Recurrence quantification analysis of complex‐fractionated electrograms differentiates active and passive sites during atrial fibrillation. Journal Of Cardiovascular Electrophysiology 2019, 30: 2229-2238. PMID: 31507008, DOI: 10.1111/jce.14161.Peer-Reviewed Original Research
2015
Randomized trial of atrial arrhythmia monitoring to guide anticoagulation in patients with implanted defibrillator and cardiac resynchronization devices
Martin DT, Bersohn MM, Waldo AL, Wathen MS, Choucair WK, Lip GY, Ip J, Holcomb R, Akar JG, Halperin JL. Randomized trial of atrial arrhythmia monitoring to guide anticoagulation in patients with implanted defibrillator and cardiac resynchronization devices. European Heart Journal 2015, 36: 1660-1668. PMID: 25908774, DOI: 10.1093/eurheartj/ehv115.Peer-Reviewed Original ResearchConceptsAtrial tachyarrhythmiasMajor bleedingImplanted defibrillatorsInterruption of anticoagulationRemote rhythm monitoringStandard clinical criteriaCardiac resynchronization devicesAT burdenSystemic embolismThromboembolism ratesPrimary endpointComposite endpointBiventricular defibrillatorMedian timeAtrial fibrillationClinical criteriaResynchronization devicesEarly initiationAnticoagulationRhythm monitoringBleedingPatientsPrimary analysisControl groupAtrial electrograms
2008
Prospective Study of Atrial Fibrillation Termination During Ablation Guided by Automated Detection of Fractionated Electrograms
PORTER M, SPEAR W, AKAR JG, HELMS R, BRYSIEWICZ N, SANTUCCI P, WILBER DJ. Prospective Study of Atrial Fibrillation Termination During Ablation Guided by Automated Detection of Fractionated Electrograms. Journal Of Cardiovascular Electrophysiology 2008, 19: 613-620. PMID: 18462320, DOI: 10.1111/j.1540-8167.2008.01189.x.Peer-Reviewed Original ResearchConceptsPersistent atrial fibrillationAtrial fibrillationParoxysmal atrial fibrillationInitial AF ablationOne-year freedomRecurrent atrial arrhythmiasSingle-procedure outcomesAntiarrhythmic drug therapySelection of patientsSpontaneous atrial fibrillationSites/patientAF termination rateHigher AF termination rateAtrial fibrillation terminationAF ablationProspective studyAtrial arrhythmiasPulmonary veinsDrug therapyAdditional ablationAtrial septumProcedure outcomesPatientsAtrial electrogramsCFAE sitesElectrogram‐Guided Approach to Ablation of Atrial Fibrillation
Wilber D, Akar J, Santucci P, Brysiewicz N. Electrogram‐Guided Approach to Ablation of Atrial Fibrillation. 2008, 240-255. DOI: 10.1002/9781444300185.ch18.Peer-Reviewed Original Research
2002
Use of global atrial fibrillation organization to optimize the success of burst pace termination
Everett TH, Akar JG, Kok LC, Moorman JR, Haines DE. Use of global atrial fibrillation organization to optimize the success of burst pace termination. Journal Of The American College Of Cardiology 2002, 40: 1831-1840. PMID: 12446068, DOI: 10.1016/s0735-1097(02)02476-2.Peer-Reviewed Original ResearchConceptsAtrial fibrillationRight atriumPace terminationBiatrial pacingAtrial conduction blockSuccess rateBipolar atrial electrogramOverall success rateOrganization indexAtrial pacingDecapolar catheterConduction blockAtrial electrogramsBurst terminationElectrogram recordingsPacingHigh efficacyAtrial fibrillation organizationFibrillationEffect of Electrical and Structural Remodeling on Spatiotemporal Organization in Acute and Persistent Atrial Fibrillation
AKAR JG, EVERETT TH, KOK L, MOORMAN JR, HAINES DE. Effect of Electrical and Structural Remodeling on Spatiotemporal Organization in Acute and Persistent Atrial Fibrillation. Journal Of Cardiovascular Electrophysiology 2002, 13: 1027-1034. PMID: 12435191, DOI: 10.1046/j.1540-8167.2002.01027.x.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAnimalsAtrial FibrillationAtrial FunctionDisease Models, AnimalDogsElectrocardiographyElectrophysiologic Techniques, CardiacEntropyFemaleFollow-Up StudiesHeart AtriaModels, CardiovascularRecovery of FunctionRefractory Period, ElectrophysiologicalSeverity of Illness IndexStatistics as TopicTreatment OutcomeConceptsAtrial effective refractory periodPersistent atrial fibrillationAcute atrial fibrillationAtrial fibrillationStructural remodelingSinus rhythmMean atrial effective refractory periodEffective refractory periodAtrial sizeElectrical remodelingLeft atriumBasket catheterAF dogsIntracardiac echocardiographyAtrial electrogramsRefractory periodRemodelingFibrillationSpatiotemporal organizationRhythmAcuteEchocardiographyCatheterMajor roleRecovery