2020
Understanding tricuspid valve remodelling in atrial fibrillation using three-dimensional echocardiography.
Ortiz-Leon XA, Posada-Martinez EL, Trejo-Paredes MC, Ivey-Miranda JB, Pereira J, Crandall I, DaSilva P, Bouman E, Brooks A, Gerardi C, Ugonabo I, Chen W, Houle H, Akar JG, Lin BA, McNamara RL, Lombo-Lievano B, Arias-Godinez JA, Sugeng L. Understanding tricuspid valve remodelling in atrial fibrillation using three-dimensional echocardiography. European Heart Journal - Cardiovascular Imaging 2020, 21: 747-755. PMID: 32372089, DOI: 10.1093/ehjci/jeaa058.Peer-Reviewed Original ResearchConceptsLeft heart diseaseSevere tricuspid regurgitationTricuspid regurgitationAtrial fibrillationTransoesophageal echocardiographyBiatrial dilatationHigher systolic pulmonary artery pressureNormal right ventricular sizeSystolic pulmonary artery pressureImpact of AFSevere functional tricuspid regurgitationTricuspid annulus dilationPulmonary artery pressureRight ventricular sizeFunctional tricuspid regurgitationFractional area changeTA fractional area changeThree-dimensional echocardiographyRV enlargementArtery pressureBiventricular functionTricuspid valveVentricular sizeAF groupSinus rhythm
2008
Acute Onset Human Atrial Fibrillation Is Associated With Local Cardiac Platelet Activation and Endothelial Dysfunction
Akar JG, Jeske W, Wilber DJ. Acute Onset Human Atrial Fibrillation Is Associated With Local Cardiac Platelet Activation and Endothelial Dysfunction. Journal Of The American College Of Cardiology 2008, 51: 1790-1793. PMID: 18452786, DOI: 10.1016/j.jacc.2007.11.083.Peer-Reviewed Original ResearchConceptsAcute onset atrial fibrillationSystemic platelet activationRisk factorsPlatelet activationHypercoagulable stateAtrial fibrillationAF groupThrombin generationBlood samplesControl groupUnderwent radiofrequency catheter ablationPlatelet P-selectin expressionOnset atrial fibrillationBaseline blood samplesRadiofrequency catheter ablationMinutes of onsetBeats/minP-selectin expressionBurst atrial pacingHuman atrial fibrillationNitric oxide productionEnzyme-linked immunosorbentLocal thrombin generationInflammatory markersProthrombotic state