1998
Interferon Induction of TAP1
Min W, Pober J, Johnson D. Interferon Induction of TAP1. Circulation Research 1998, 83: 815-823. PMID: 9776728, DOI: 10.1161/01.res.83.8.815.Peer-Reviewed Original ResearchMeSH KeywordsATP Binding Cassette Transporter, Subfamily B, Member 2ATP-Binding Cassette TransportersDimerizationDNA-Binding ProteinsEndotheliumGene Expression Regulation, EnzymologicGenes, ReporterHeLa CellsHumansInterferon-alphaInterferon-betaInterferon-gammaInterferon-Stimulated Gene Factor 3Interferon-Stimulated Gene Factor 3, gamma SubunitIntracellular Signaling Peptides and ProteinsJanus Kinase 1Janus Kinase 2Major Histocompatibility ComplexPromoter Regions, GeneticProtein Tyrosine Phosphatase, Non-Receptor Type 11Protein Tyrosine Phosphatase, Non-Receptor Type 6Protein Tyrosine PhosphatasesProtein-Tyrosine KinasesProto-Oncogene ProteinsRNA, MessengerSH2 Domain-Containing Protein Tyrosine PhosphatasesSignal TransductionSrc Homology DomainsSTAT1 Transcription FactorSTAT2 Transcription FactorTrans-ActivatorsTranscription Factors
1997
Vascular cells have limited capacities to activate and differentiate T cells: Implications for transplant vascular sclerosis
Pober J, Ma W, Biedermann B, Libby P. Vascular cells have limited capacities to activate and differentiate T cells: Implications for transplant vascular sclerosis. Transplant Immunology 1997, 5: 251-254. PMID: 9504143, DOI: 10.1016/s0966-3274(97)80004-4.Peer-Reviewed Original Research
1991
Tumor necrosis factor regulation of major histocompatibility complex gene expression
Johnson D, Pober J. Tumor necrosis factor regulation of major histocompatibility complex gene expression. Immunologic Research 1991, 10: 141. PMID: 1655923, DOI: 10.1007/bf02918161.Peer-Reviewed Original ResearchAnimalsBase SequenceGene Expression RegulationHumansMajor Histocompatibility ComplexMiceMolecular Sequence DataOncogenesReceptors, Cell SurfaceReceptors, Tumor Necrosis FactorRNA Processing, Post-TranscriptionalSecond Messenger SystemsSequence Homology, Nucleic AcidTranscription FactorsTranscription, GeneticTumor Necrosis Factor-alpha
1990
The Endothelial Cell as a Regulator of T‐Cell Function
Hughes. C, Savage C, Pober JS. The Endothelial Cell as a Regulator of T‐Cell Function. Immunological Reviews 1990, 117: 85-102. PMID: 2258192, DOI: 10.1111/j.1600-065x.1990.tb00568.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigen-Presenting CellsAntigens, Differentiation, T-LymphocyteEndothelium, VascularHumansMajor Histocompatibility ComplexReceptors, ImmunologicT-LymphocytesConceptsIL-2 productionT cell IL-2 productionT cellsClass II moleculesLFA-3Peripheral blood mononuclear cellsAntigen-presenting capacityMemory T cellsMHC class II moleculesBlood mononuclear cellsNon-immune cell typesT cell functionNon-polymorphic regionsT cell linesCostimulatory cellsMononuclear cellsIL-2Allospecific CTLICAM-1IFN-gammaVCAM-1Immunosuppressive drug CsAAbility of ECCostimulator activityVLA-4
1984
Immune interferon activates multiple class II major histocompatibility complex genes and the associated invariant chain gene in human endothelial cells and dermal fibroblasts.
Collins T, Korman AJ, Wake CT, Boss JM, Kappes DJ, Fiers W, Ault KA, Gimbrone MA, Strominger JL, Pober JS. Immune interferon activates multiple class II major histocompatibility complex genes and the associated invariant chain gene in human endothelial cells and dermal fibroblasts. Proceedings Of The National Academy Of Sciences Of The United States Of America 1984, 81: 4917-4921. PMID: 6431411, PMCID: PMC391603, DOI: 10.1073/pnas.81.15.4917.Peer-Reviewed Original ResearchConceptsAntigen expressionIFN-gammaSurface expressionClass II major histocompatibility complex antigensClass II antigen expressionImmune interferonClass II MHC antigensEndothelial cellsMajor histocompatibility complex antigensImmune accessory functionHLA-DR antigensClass II antigensHistocompatibility complex antigensVascular endothelial cellsHLA-DCDermal fibroblastsHuman endothelial cellsHLA-DRMHC antigensII antigensComplex antigensB antigensDe novo appearanceClass IIStromal cells