1989
Functions of vascular wall cells related to development of transplantation-associated coronary arteriosclerosis.
Libby P, Salomon RN, Payne DD, Schoen FJ, Pober JS. Functions of vascular wall cells related to development of transplantation-associated coronary arteriosclerosis. Transplantation Proceedings 1989, 21: 3677-84. PMID: 2669279.Peer-Reviewed Original ResearchConceptsArterial diseaseT cellsVascular cellsChronic immune reactionsTransplantation-associated arteriosclerosisTypical acute rejectionDelayed-type hypersensitivityHelper T cellsWall cellsClass II HLACytolytic T cellsVascular wall cellsClass I HLAVessel wall cellsUnderstanding of atherogenesisAcute rejectionGraft arteryCoronary arteriosclerosisCoronary atherosclerosisBasic pathobiologyCellular immunityImmune activationSelective therapeutic strategiesCoronary circulationAccelerated disease
1986
Two monokines, interleukin 1 and tumor necrosis factor, render cultured vascular endothelial cells susceptible to lysis by antibodies circulating during Kawasaki syndrome.
Leung DY, Geha RS, Newburger JW, Burns JC, Fiers W, Lapierre LA, Pober JS. Two monokines, interleukin 1 and tumor necrosis factor, render cultured vascular endothelial cells susceptible to lysis by antibodies circulating during Kawasaki syndrome. Journal Of Experimental Medicine 1986, 164: 1958-1972. PMID: 3491174, PMCID: PMC2188474, DOI: 10.1084/jem.164.6.1958.Peer-Reviewed Original ResearchConceptsAcute Kawasaki syndromeTumor necrosis factorKawasaki syndromeHuman endothelial cellsIL-1Cytotoxic antibodiesImmune activationEndothelial cellsNecrosis factorTarget antigenComplement-dependent cytotoxic activityAcute febrile illnessEndothelial cell antigensVascular smooth muscle cellsAge-matched controlsMonocytes/macrophagesSmooth muscle cellsCultured vascular endothelial cellsVascular endothelial cellsComplement-mediated killingDiffuse vasculitisConvalescent phaseFebrile illnessAcute phaseVascular injury