IL-8 and angiogenesis: evidence that human endothelial cells lack receptors and do not respond to IL-8 in vitro
Petzelbauer P, Watson C, Watson C, Pfau S, Pober J. IL-8 and angiogenesis: evidence that human endothelial cells lack receptors and do not respond to IL-8 in vitro. Cytokine 1995, 7: 267-272. PMID: 7543779, DOI: 10.1006/cyto.1995.0031.Peer-Reviewed Original ResearchConceptsHuman umbilical vein endothelial cellsIL-8Cultured human umbilical vein endothelial cellsDermal microvascular endothelial cellsEndothelial cellsHuman endothelial cellsRecombinant human IL-8IL-8 treatmentMicrovascular human endothelial cellsReceptor mRNA expressionEndothelial cell growth factorHuman IL-8Human dermal microvascular endothelial cellsMicrovascular endothelial cellsCytoplasmic calcium concentrationUmbilical vein endothelial cellsCell growth factorVein endothelial cellsAngiogenic factorsMRNA expressionDirect actionGrowth factorCalcium concentrationIndirect actionProliferative rate