Human dermal fibroblasts present tetanus toxoid antigen to antigen-specific T cell clones.
Umetsu DT, Pober JS, Jabara HH, Fiers W, Yunis EJ, Burakoff SJ, Reiss CS, Geha RS. Human dermal fibroblasts present tetanus toxoid antigen to antigen-specific T cell clones. Journal Of Clinical Investigation 1985, 76: 254-260. PMID: 3160726, PMCID: PMC423759, DOI: 10.1172/jci111955.Peer-Reviewed Original ResearchConceptsAntigen-presenting cellsTetanus toxoidProliferative responseClassical antigen-presenting cellsAntigen-specific proliferative responsesAntigen-specific T cell clonesHLA-DR antigensHelper T cellsTetanus toxoid antigenT cell proliferationT cell clonesHuman dermal fibroblastsPresent tetanus toxoidMonoclonal antibody OKM1Cultured human dermal fibroblastsDermal fibroblastsLeu-M1DR expressionHLA-DRUbiquitous cell typeAntigen presentationT cellsToxoid antigenSephadex G10 columnImmune interferon