Endothelial cell lymphocyte function-associated antigen-3 and an unidentified ligand act in concert to provide costimulation to human peripheral blood CD4+ T cells
Savage C, Hughes C, Pepinsky R, Wallner B, Freedman A, Pober J. Endothelial cell lymphocyte function-associated antigen-3 and an unidentified ligand act in concert to provide costimulation to human peripheral blood CD4+ T cells. Cellular Immunology 1991, 137: 150-163. PMID: 1679377, DOI: 10.1016/0008-8749(91)90065-j.Peer-Reviewed Original ResearchConceptsLymphocyte function-associated antigen-3Adhesion molecule-1T cellsEndothelial cellsMolecule-1Antigen 3Human peripheral blood CD4Vascular cell adhesion molecule-1Intercellular adhesion molecule-1Cell adhesion molecule-1Peripheral blood CD4T cell populationsB7/BB1Cultured human endothelial cellsIL-2 synthesisBlood CD4EC costimulationHuman endothelial cellsT cell CD2IL-2CD4CostimulationCell populationsComparable degreeLines of evidence