Cultured human endothelial cells express platelet-derived growth factor B chain: cDNA cloning and structural analysis
Collins T, Ginsburg D, Boss J, Orkin S, Pober J. Cultured human endothelial cells express platelet-derived growth factor B chain: cDNA cloning and structural analysis. Nature 1985, 316: 748-750. PMID: 4033772, DOI: 10.1038/316748a0.Peer-Reviewed Original ResearchConceptsHuman endothelial cellsSequence analysisB chainComplementary DNA clonePDGF B-chainApparent relative molecular massEndothelial cellsChains of PDGFRelative molecular massNorthern blot analysisComplete sequence analysisNormal human endothelial cellsPlatelet-derived growth factorPlatelet-derived growth factor B-chainGrowth factor B-chainDNA clonesPrecursor polypeptideCDNA cloningStriking homologyVascular smooth muscle cellsProtein productsMolecular massPolypeptide chainMessenger RNACultured human endothelial cells