Human endothelial cells augment early CD40 ligand expression in activated CD4+ T cells through LFA-3-mediated stabilization of mRNA.
Murakami K, Ma W, Fuleihan R, Pober J. Human endothelial cells augment early CD40 ligand expression in activated CD4+ T cells through LFA-3-mediated stabilization of mRNA. The Journal Of Immunology 1999, 163: 2667-73. PMID: 10453007, DOI: 10.4049/jimmunol.163.5.2667.Peer-Reviewed Original ResearchConceptsCD40 ligand expressionT cellsCD40L mRNALFA-3CD40L expressionICAM-1Ligand expressionICAM-1 antisense oligonucleotideT-cell mRNA expressionCD40L protein expressionPretreatment of ECPromoter-reporter geneHuman endothelial cellsIL-2CD4Capacity of ECMRNA expressionICAM-2Endothelial cellsProtein expressionCD40LAntisense oligonucleotidePHAMRNACells