1991
Immunologic Interactions of T Lymphocytes with Vascular Endothelium
Pober J, Cotran R. Immunologic Interactions of T Lymphocytes with Vascular Endothelium. Advances In Immunology 1991, 50: 261-302. PMID: 1950797, DOI: 10.1016/s0065-2776(08)60827-5.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsMemory T cellsT cellsVascular endotheliumPrimary antigen-presenting cellsAntigen-presenting functionAntigen-presenting cellsNaive T cellsContext of transplantationEffective T cell activationCultured human endothelial cellsT cell activationVivo immune systemLymph nodesHuman endothelial cellsHypersensitivity reactionsImmunologic interactionsIL-8Preferential homingT lymphocytesInflammatory sitesAntigen specificityImmune systemRejection reactionCell activationMemory responses
1986
Physiologic Regulation of Class II Major Histocompatibility Complex Gene Expression
Collins T, Pober J, Strominger J. Physiologic Regulation of Class II Major Histocompatibility Complex Gene Expression. 1986, 14-31. DOI: 10.1007/978-3-642-70367-6_2.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsClass II determinantsNominal antigenMajor histocompatibility complexSpecific effector cellsClass II major histocompatibility complexT helper cellsAntigen-presenting cellsClass II antigensCase of transplantationMajor histocompatibility complex gene expressionT-inducer cellsClass II major histocompatibility complex gene expressionT cell antigen receptorAccessory capacityEffector cellsAllogeneic responseHelper cellsInducer cellsII antigensImmune responsivenessImmune systemCell antigen receptorAntigenAntigen receptorHistocompatibility complex
1985
Human dermal fibroblasts present tetanus toxoid antigen to antigen-specific T cell clones.
Umetsu DT, Pober JS, Jabara HH, Fiers W, Yunis EJ, Burakoff SJ, Reiss CS, Geha RS. Human dermal fibroblasts present tetanus toxoid antigen to antigen-specific T cell clones. Journal Of Clinical Investigation 1985, 76: 254-260. PMID: 3160726, PMCID: PMC423759, DOI: 10.1172/jci111955.Peer-Reviewed Original ResearchConceptsAntigen-presenting cellsTetanus toxoidProliferative responseClassical antigen-presenting cellsAntigen-specific proliferative responsesAntigen-specific T cell clonesHLA-DR antigensHelper T cellsTetanus toxoid antigenT cell proliferationT cell clonesHuman dermal fibroblastsPresent tetanus toxoidMonoclonal antibody OKM1Cultured human dermal fibroblastsDermal fibroblastsLeu-M1DR expressionHLA-DRUbiquitous cell typeAntigen presentationT cellsToxoid antigenSephadex G10 columnImmune interferon