2018
Predicting Adverse Outcomes After Total Hip Arthroplasty: A Comparison of Demographics, the American Society of Anesthesiologists class, the Modified Charlson Comorbidity Index, and the Modified Frailty Index.
Ondeck NT, Bohl DD, Bovonratwet P, Anandasivam NS, Cui JJ, McLynn RP, Grauer JN. Predicting Adverse Outcomes After Total Hip Arthroplasty: A Comparison of Demographics, the American Society of Anesthesiologists class, the Modified Charlson Comorbidity Index, and the Modified Frailty Index. Journal Of The American Academy Of Orthopaedic Surgeons 2018, 26: 735-743. PMID: 30130353, DOI: 10.5435/jaaos-d-17-00009.Peer-Reviewed Original ResearchConceptsCharlson Comorbidity IndexTotal hip arthroplastyComorbidity indexAdverse outcomesAdverse eventsFrailty indexAnesthesiologists classTHA patientsHip arthroplastyModified Charlson Comorbidity IndexGeneral health complicationsModified Frailty IndexPerioperative adverse outcomesMinor adverse eventsExtended hospital staySevere adverse eventsHigh-level careComparison of demographicsAmerican SocietyDiscriminative abilityPatients ASAHospital stayPerioperative outcomesGreater discriminative abilityHealth complicationsDiscriminative Ability for Adverse Outcomes After Surgical Management of Hip Fractures
Ondeck NT, Bovonratwet P, Ibe IK, Bohl DD, McLynn RP, Cui JJ, Baumgaertner MR, Grauer JN. Discriminative Ability for Adverse Outcomes After Surgical Management of Hip Fractures. Journal Of Orthopaedic Trauma 2018, 32: 231-237. PMID: 29401098, DOI: 10.1097/bot.0000000000001140.Peer-Reviewed Original ResearchConceptsElixhauser comorbidity measuresCharlson Comorbidity IndexExtended hospital stayAdverse outcomesHip fractureComorbidity indexAdverse eventsSurgical managementLargest discriminative abilityHospital stayDiscriminative abilityDemographic factorsHospital adverse outcomesPrognostic Level IIIHip fracture surgeryMinor adverse eventsSevere adverse eventsHip fracture studiesNational Inpatient SampleOverall discriminative abilityAppropriate patient expectationsPostoperative complicationsFrailty indexFracture surgeryMedical managementDialysis Patients Undergoing Total Knee Arthroplasty Have Significantly Increased Odds of Perioperative Adverse Events Independent of Demographic and Comorbidity Factors
Ottesen TD, Zogg CK, Haynes MS, Malpani R, Bellamkonda KS, Grauer JN. Dialysis Patients Undergoing Total Knee Arthroplasty Have Significantly Increased Odds of Perioperative Adverse Events Independent of Demographic and Comorbidity Factors. The Journal Of Arthroplasty 2018, 33: 2827-2834. PMID: 29754981, DOI: 10.1016/j.arth.2018.04.012.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overArthroplasty, Replacement, KneeComorbidityElective Surgical ProceduresFemaleHumansInpatientsLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPatient DischargePatient ReadmissionPostoperative ComplicationsQuality ImprovementRegression AnalysisRenal DialysisReoperationRetrospective StudiesRisk AssessmentConceptsTotal knee arthroplastyDialysis-dependent patientsAdverse eventsPatient demographicsDialysis patientsAdverse outcomesKnee arthroplastyNational Surgical Quality Improvement Program databaseOverall healthRisk-adjusted logistic regressionElective total knee arthroplastyQuality Improvement Program databaseImprovement Program databaseMinor adverse eventsNational inpatient databaseSevere adverse eventsBone health statusNondialysis cohortNondialysis patientsPerioperative periodTKA patientsAdult patientsPreoperative riskComorbidity factorsInstitutional cohortThe Rothman Index Is Associated With Postdischarge Adverse Events After Hip Fracture Surgery in Geriatric Patients
McLynn RP, Ottesen TD, Ondeck NT, Cui JJ, Rubin LE, Grauer JN. The Rothman Index Is Associated With Postdischarge Adverse Events After Hip Fracture Surgery in Geriatric Patients. Clinical Orthopaedics And Related Research® 2018, 476: 997-1006. PMID: 29419631, PMCID: PMC5916609, DOI: 10.1007/s11999.0000000000000186.Peer-Reviewed Original ResearchConceptsRothman Index scoresPostdischarge adverse eventsHip fracture surgeryPostdischarge adverse outcomesAdverse eventsASA classRothman IndexHip fractureFracture surgeryIndex scoreGeriatric patientsAdverse outcomesMedical CenterOverall patient statusHip fracture careRoutine laboratory valuesMeasures of comorbidityRisk of complicationsBody mass indexAge 65 yearsPlan of careVulnerable patient populationCondition of patientsAcademic medical centerElectronic medical recordsHow Common—and How Serious— Is Clostridium difficile Colitis After Geriatric Hip Fracture? Findings from the NSQIP Dataset
Bovonratwet P, Bohl DD, Russo GS, Ondeck NT, Nam D, Della Valle CJ, Grauer JN. How Common—and How Serious— Is Clostridium difficile Colitis After Geriatric Hip Fracture? Findings from the NSQIP Dataset. Clinical Orthopaedics And Related Research® 2018, 476: 453-462. PMID: 29443839, PMCID: PMC6260047, DOI: 10.1007/s11999.0000000000000099.Peer-Reviewed Original ResearchConceptsHip fracture surgeryClostridium difficile colitisDifficile colitisGeriatric hip fracturesChronic care facilitiesHip fractureFracture surgeryPostoperative lengthGeriatric patientsHigh riskPreoperative anemiaCurrent smokersCare facilitiesStrict hand hygieneProphylactic antibiotic regimensFuture prospective studiesHospital quality metricsLarge database studiesStepwise multivariate modelLarge national databasePostdischarge dataAntibiotic regimensInfectious diagnosisPreoperative factorsProphylactic antibioticsMissing data may lead to changes in hip fracture database studies: a study of the American College of Surgeons National Surgical Quality Improvement Program.
Basques BA, McLynn RP, Lukasiewicz AM, Samuel AM, Bohl DD, Grauer JN. Missing data may lead to changes in hip fracture database studies: a study of the American College of Surgeons National Surgical Quality Improvement Program. The Bone & Joint Journal 2018, 100-B: 226-232. PMID: 29437066, DOI: 10.1302/0301-620x.100b2.bjj-2017-0791.r1.Peer-Reviewed Original ResearchConceptsAdverse eventsRisk factorsDatabase studyNational Surgical Quality Improvement Program databaseSurgeons National Surgical Quality Improvement ProgramNational Surgical Quality Improvement ProgramQuality Improvement Program databaseSurgical Quality Improvement ProgramPostoperative adverse eventsImprovement Program databaseNational database studyDifferent risk factorsMultivariate regressionQuality Improvement ProgramElderly patientsNSQIP databaseBone JointProgram databaseLaboratory valuesAmerican CollegePatientsHipFracturesComorbiditiesSurgery
2017
Results of Database Studies in Spine Surgery Can Be Influenced by Missing Data
Basques BA, McLynn RP, Fice MP, Samuel AM, Lukasiewicz AM, Bohl DD, Ahn J, Singh K, Grauer JN. Results of Database Studies in Spine Surgery Can Be Influenced by Missing Data. Clinical Orthopaedics And Related Research® 2017, 475: 2893-2904. PMID: 27896677, PMCID: PMC5670041, DOI: 10.1007/s11999-016-5175-7.Peer-Reviewed Original ResearchMeSH KeywordsComorbidityData AccuracyData CollectionData MiningDatabases, FactualDecision Support TechniquesHumansLength of StayLogistic ModelsMultivariate AnalysisOdds RatioOperative TimeOrthopedic ProceduresPostoperative ComplicationsPredictive Value of TestsProcess Assessment, Health CareRetrospective StudiesRisk AssessmentRisk FactorsSpinal DiseasesSpineTime FactorsTreatment OutcomeUnited StatesConceptsACS-NSQIP databaseAdverse eventsPreoperative laboratory valuesRisk factorsSpine surgeryOperating room timeLaboratory valuesSpine studiesACS-NSQIPDatabase studyRoom timeReference rangeQuality Improvement Program databasePerioperative laboratory valuesVariable reference rangesAnterior cervical discectomyImprovement Program databaseMost risk factorsLength of stayLarge database studiesDifferent risk factorsEffect sizeCervical discectomyMedical comorbiditiesGreater effect sizeWhat Is the Timing of General Health Adverse Events That Occur After Total Joint Arthroplasty?
Bohl DD, Ondeck NT, Basques BA, Levine BR, Grauer JN. What Is the Timing of General Health Adverse Events That Occur After Total Joint Arthroplasty? Clinical Orthopaedics And Related Research® 2017, 475: 2952-2959. PMID: 28054326, PMCID: PMC5670043, DOI: 10.1007/s11999-016-5224-2.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overArthroplasty, Replacement, HipArthroplasty, Replacement, KneeData MiningDatabases, FactualHumansLength of StayMiddle AgedMultivariate AnalysisPatient DischargePostoperative ComplicationsProcess Assessment, Health CareProportional Hazards ModelsRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesYoung AdultConceptsTotal joint arthroplastyAdverse eventsDays of diagnosisDeep vein thrombosisPulmonary embolismPostoperative dayVein thrombosisMyocardial infarctionJoint arthroplastySurgeons National Surgical Quality Improvement ProgramNational Surgical Quality Improvement ProgramMultivariate Cox proportional hazardsSurgical Quality Improvement ProgramMedian postoperative dayPulmonary embolism 3Postoperative adverse eventsSurgical site infectionMyocardial infarction 3Different adverse eventsRetrospective database analysisLife-threatening findingsCertain adverse eventsCox proportional hazardsSuch adverse eventsQuality Improvement Program
2016
Demographics, Mechanisms of Injury, and Concurrent Injuries Associated With Calcaneus Fractures: A Study of 14 516 Patients in the American College of Surgeons National Trauma Data Bank
Bohl DD, Ondeck NT, Samuel AM, Diaz-Collado PJ, Nelson SJ, Basques BA, Leslie MP, Grauer JN. Demographics, Mechanisms of Injury, and Concurrent Injuries Associated With Calcaneus Fractures: A Study of 14 516 Patients in the American College of Surgeons National Trauma Data Bank. Foot & Ankle Specialist 2016, 10: 402-410. PMID: 27895200, DOI: 10.1177/1938640016679703.Peer-Reviewed Original ResearchConceptsNational Trauma Data BankSurgeons National Trauma Data BankTrauma Data BankCalcaneus fracturesConcurrent injuriesNonorthopaedic injuriesSpine fracturesAmerican CollegeMechanism of injuryLower extremity fracturesLumbar spine fracturesCommon comorbiditiesFracture patientsExtremity fracturesOrgan injuryRetrospective reviewNational sampleHead injuryHigh incidenceInjury mechanismPatientsLevel IIIInjuryHospital departmentsStrong associationNationwide Databases in Orthopaedic Surgery Research
Bohl DD, Singh K, Grauer JN. Nationwide Databases in Orthopaedic Surgery Research. Journal Of The American Academy Of Orthopaedic Surgeons 2016, 24: 673-682. PMID: 27579813, DOI: 10.5435/jaaos-d-15-00217.Peer-Reviewed Original Research
2015
Overall Similar Infection Rates Reported in the Physician-reported Scoliosis Research Society Database and the Chart-abstracted American College of Surgeons National Surgical Quality Improvement Program Database
Webb ML, Lukasiewicz AM, Samuel AM, Bohl DD, Basques BA, Varthi AG, Grauer JN. Overall Similar Infection Rates Reported in the Physician-reported Scoliosis Research Society Database and the Chart-abstracted American College of Surgeons National Surgical Quality Improvement Program Database. Spine 2015, 40: 1431-1435. PMID: 26110664, DOI: 10.1097/brs.0000000000001033.Peer-Reviewed Original ResearchConceptsACS-NSQIP databaseSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseImprovement Program databaseInfection rateSRS databasePostoperative infectionProgram databaseAmerican CollegeScoliosis Research Society MorbidityAcute postoperative infectionSurgeon-reported dataPostoperative infection rateRetrospective cohort studyNinth Revision codesSimilar infection ratesDegenerative spondylolithesisCohort studyScheuermann's kyphosisSurgical databaseRevision codesSurgical correctionBACKGROUND DATASurgical casesAnalysis of Delays to Surgery for Cervical Spinal Cord Injuries
Samuel AM, Bohl DD, Basques BA, Diaz-Collado PJ, Lukasiewicz AM, Webb ML, Grauer JN. Analysis of Delays to Surgery for Cervical Spinal Cord Injuries. Spine 2015, 40: 992-1000. PMID: 25785963, DOI: 10.1097/brs.0000000000000883.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overCervical VertebraeChi-Square DistributionComorbidityDatabases, FactualDecompression, SurgicalFemaleHumansKaplan-Meier EstimateLinear ModelsMaleMiddle AgedMultivariate AnalysisPatient AdmissionRetrospective StudiesRisk AssessmentRisk FactorsSpinal Cord InjuriesTime FactorsTime-to-TreatmentTreatment OutcomeYoung AdultConceptsCervical spinal cord injuryIncomplete spinal cord injurySpinal cord injuryNational Trauma Data Bank Research Data SetCentral spinal cord injuryComplete spinal cord injuryLate surgeryCord injuryUpper cervical spinal cord injuryGreater Charlson Comorbidity IndexSuperior neurological outcomeCharlson Comorbidity IndexMajority of patientsComorbidity indexNeurological outcomeUnderwent surgerySurgical timingInjury characteristicsRetrospective studyEmergency departmentInpatient admissionsPatient populationSurgery occurBACKGROUND DATAPatients
2014
Nationwide Inpatient Sample and National Surgical Quality Improvement Program Give Different Results in Hip Fracture Studies
Bohl DD, Basques BA, Golinvaux NS, Baumgaertner MR, Grauer JN. Nationwide Inpatient Sample and National Surgical Quality Improvement Program Give Different Results in Hip Fracture Studies. Clinical Orthopaedics And Related Research® 2014, 472: 1672-1680. PMID: 24615426, PMCID: PMC4016448, DOI: 10.1007/s11999-014-3559-0.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overComorbidityData MiningDatabases, FactualEvidence-Based MedicineFemaleFracture FixationHip FracturesHospitalizationHumansInpatientsLength of StayMaleMiddle AgedOutcome and Process Assessment, Health CarePostoperative ComplicationsPrevalenceQuality ImprovementQuality Indicators, Health CareReproducibility of ResultsRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesConceptsNational Surgical Quality Improvement ProgramNationwide Inpatient SampleSurgical Quality Improvement ProgramInpatient adverse eventsAcute kidney injuryPeripheral vascular diseaseAdverse eventsUrinary tract infectionQuality Improvement ProgramKidney injuryNSQIP databaseTract infectionsInpatient SampleVascular diseaseMethodsA retrospective cohort studyQuestions/PurposesThe purposeRetrospective cohort studyStatistical differenceTerms of comorbiditiesSurgical site infectionHip fracture studiesIntertrochanteric hip fracturesLength of stayGreat clinical importanceTerms of demographicsUsing the ACS-NSQIP to Identify Factors Affecting Hospital Length of Stay After Elective Posterior Lumbar Fusion
Basques BA, Fu MC, Buerba RA, Bohl DD, Golinvaux NS, Grauer JN. Using the ACS-NSQIP to Identify Factors Affecting Hospital Length of Stay After Elective Posterior Lumbar Fusion. Spine 2014, 39: 497-502. PMID: 24384669, PMCID: PMC3961012, DOI: 10.1097/brs.0000000000000184.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedBlood TransfusionBody Mass IndexChi-Square DistributionComorbidityDecision Support TechniquesElective Surgical ProceduresFemaleHumansLength of StayLinear ModelsLumbar VertebraeMaleMiddle AgedMultivariate AnalysisObesity, MorbidOperative TimePatient SelectionRetrospective StudiesRisk AssessmentRisk FactorsSpinal DiseasesSpinal FusionTime FactorsTreatment OutcomeUnited StatesConceptsElective posterior lumbar fusionPosterior lumbar fusionNational Surgical Quality Improvement Program databaseSurgeons National Surgical Quality Improvement Program databaseQuality Improvement Program databaseImprovement Program databaseLumbar fusionHospital lengthIntraoperative variablesExtended LOSProgram databaseAmerican CollegePosterior lumbar spine fusionPredictors of LOSRetrospective cohort studyBody mass indexLumbar spine fusionCommon surgical procedureImportant clinical variablesInpatient hospital costsLumbar spine pathologyAnesthesiologists classIntraoperative transfusionMorbid obesityCohort study
2008
MR Findings of Exaggerated Fluid in Facet Joints Predicts Instability
Schinnerer KA, Katz LD, Grauer JN. MR Findings of Exaggerated Fluid in Facet Joints Predicts Instability. Clinical Spine Surgery A Spine Publication 2008, 21: 468-472. PMID: 18836356, DOI: 10.1097/bsd.0b013e3181585bab.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingFacet jointsPlain filmsLumbar spine magnetic resonance imagingLumbar magnetic resonance imagingSpine magnetic resonance imagingSupine magnetic resonance imagingAxial magnetic resonance imagingConsecutive magnetic resonance imagingLow back painLumbar facet jointsRetrospective radiographic reviewIncidence of spondylolisthesisRadiographic evidenceSingle surgeonBack painRadiographic reviewSagittal MRI sequencesBACKGROUND DATAMR findingsSpondylolisthesisResonance imagingCorresponding radiographsSubtle instabilityRelative incidence
2004
Pathophysiology and pharmacologic treatment of acute spinal cord injury
Kwon BK, Tetzlaff W, Grauer JN, Beiner J, Vaccaro AR. Pathophysiology and pharmacologic treatment of acute spinal cord injury. The Spine Journal 2004, 4: 451-464. PMID: 15246307, DOI: 10.1016/j.spinee.2003.07.007.Peer-Reviewed Original ResearchConceptsAcute spinal cord injurySpinal cord injuryCord injuryPathophysiologic processesPharmacologic treatmentNeuroprotective agentsSecondary damageImportant pathophysiologic processSecondary injury cascadePharmacologic therapyAcute treatmentInjury cascadeNeurologic functionNeuroprotective strategiesDevastating injuriesPathophysiologic mechanismsSpecific therapyPathophysiologic eventsSpinal cordHuman trialsPotential therapyInjuryAnimal dataLiterature reviewTherapy