Second Primary Malignancies of the Bones and Joints: More Common than Expected in Osteosarcoma Patients
Freedman I, Dowd H, Dhodapkar M, Halperin S, Grauer J. Second Primary Malignancies of the Bones and Joints: More Common than Expected in Osteosarcoma Patients. JAAOS Global Research And Reviews 2023, 7: e22.00275. PMID: 36695170, PMCID: PMC9875998, DOI: 10.5435/jaaosglobal-d-22-00275.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentBone NeoplasmsChildHumansIncidenceNeoplasms, Second PrimaryOsteosarcomaSEER ProgramYoung AdultConceptsSecond primary malignanciesStandardized incidence ratiosOsteosarcoma survivorsPrimary malignancyCommon second primary malignancyNational Cancer Institute's SurveillanceEnd Results 18 databaseCommon primary bone tumorPrimary bone tumorsPopulation-level dataIncidence ratiosOverall incidenceOsteosarcoma patientsPatient populationExcess riskBone tumorsAnatomic locationLong-term eventsOsteosarcoma casesPatientsYoung adultsTumorsSoft tissueMalignancyOsteosarcoma