2010
Augmented demineralized bone matrix: a potential alternative for posterolateral lumbar spinal fusion.
Biswas D, Bible JE, Whang PH, Miller CP, Jaw R, Miller S, Grauer JN. Augmented demineralized bone matrix: a potential alternative for posterolateral lumbar spinal fusion. The American Journal Of Orthopedics 2010, 39: 531-8. PMID: 21623419.Peer-Reviewed Original ResearchConceptsFusion rateGraft alternativesPosterolateral lumbar spinal fusionLumbar spinal fusionRhBMP-2Spine fusion modelDose-response curveEctopic bone formation modelBone graft alternativesStudy ratsLumbar fusionRat modelSpinal fusionSpine fusionB graftsRecombinant human bone morphogenetic protein-2Manual palpationHuman bone morphogenetic protein-2Bone matrix productsSignificant differencesProtein 2DBM carrierBone matrixAutograftBone morphogenetic protein-2
2006
Effect of daily parathyroid hormone (1–34) on lumbar fusion in a rat model
Lawrence JP, Ennis F, White AP, Magit D, Polzhofer G, Drespe I, Troiano NW, Grauer JN. Effect of daily parathyroid hormone (1–34) on lumbar fusion in a rat model. The Spine Journal 2006, 6: 385-390. PMID: 16825043, DOI: 10.1016/j.spinee.2005.10.010.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsFemaleHumansModels, AnimalOsteocalcinPalpationParathyroid HormonePeptide FragmentsRatsRats, Sprague-DawleyRecombinant ProteinsSpinal FusionConceptsSerum osteocalcin levelsParathyroid hormoneOsteocalcin levelsFusion rateDaily injectionsManual palpationLumbar fusionRat modelIntertransverse process spinal fusionDaily parathyroid hormoneSpinal fusion outcomesPosterolateral lumbar fusionIliac crest autograftSprague-Dawley ratsPreclinical animal studiesGreater fusion rateGreat clinical valuePlacebo groupIntermittent administrationSerum osteocalcinCrest autograftAnabolic effectsSpinal fusionInjectable agentsClinical value
2005
Animal models for spinal fusion
Drespe IH, Polzhofer GK, Turner AS, Grauer JN. Animal models for spinal fusion. The Spine Journal 2005, 5: s209-s216. PMID: 16291115, DOI: 10.1016/j.spinee.2005.02.013.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements