2022
Total Hip Arthroplasty Imageless Navigation Does Not Reduce 90-Day Adverse Events or Five-Year Revisions in a Large National Cohort
Jayaram R, Gillinov S, Caruana D, Kammien A, Joo P, Rubin L, Grauer J. Total Hip Arthroplasty Imageless Navigation Does Not Reduce 90-Day Adverse Events or Five-Year Revisions in a Large National Cohort. The Journal Of Arthroplasty 2022, 38: 862-867. PMID: 36529197, DOI: 10.1016/j.arth.2022.12.012.Peer-Reviewed Original ResearchConceptsTotal hip arthroplastyAdverse eventsImageless navigationMultivariate analysisLarge national administrative databaseElixhauser comorbidity index scorePrimary total hip arthroplastyComorbidity Index scoreFive-year incidencePostoperative adverse eventsNational administrative databaseLarge national cohortLarge national databaseCause revisionTHA patientsWound dehiscenceNational cohortTHA casesAdministrative databasesDislocation rateHip arthroplastyHigher oddsNavigation groupIndex scoreComputer navigationOutcomes Following Total Hip Arthroplasty in Patients With Postpolio Syndrome: A Matched Cohort Analysis
Mercier MR, Moore HG, Wolfstadt JI, Rubin LE, Grauer JN. Outcomes Following Total Hip Arthroplasty in Patients With Postpolio Syndrome: A Matched Cohort Analysis. The Journal Of Arthroplasty 2022, 37: 1822-1826. PMID: 35447277, DOI: 10.1016/j.arth.2022.04.016.Peer-Reviewed Original ResearchConceptsTotal hip arthroplastyPostpolio syndromeUrinary tract infectionPPS patientsControl patientsProsthetic dislocationTract infectionsRevision arthroplastyHip arthroplastyFive-year postoperative periodMatched Cohort AnalysisFive-year incidencePostoperative adverse eventsLong-term outcomesBasis of ageComorbidity burdenAdverse eventsPatient demographicsPostoperative periodPostoperative surveillanceHospital readmissionHip arthritisControl cohortAdministrative databasesCohort analysisAnalysis of the frequency, characteristics, and reasons for termination of shoulder- and elbow-related clinical trials
Caruana DL, Gouzoulis MJ, McLaughlin WM, Grauer JN. Analysis of the frequency, characteristics, and reasons for termination of shoulder- and elbow-related clinical trials. Journal Of Shoulder And Elbow Surgery 2022, 31: 1922-1928. PMID: 35398166, DOI: 10.1016/j.jse.2022.02.030.Peer-Reviewed Original ResearchConceptsIndependent predictorsTrial characteristicsClinical trialsTrial terminationOdds of terminationClinical trial completionRetention of participantsResults databaseInterventional studyTrial completionMultivariate analysisAssess reasonsLogistic regressionRecruitment statusTrialsSearch termsParticipant recruitmentPredictorsShoulderIndustry sponsorshipOddsTotalCurrent studyRegistryBlindingAnalysis of the Frequency, Characteristics, and Reasons for Termination of Spine-related Clinical Trials
Caruana DL, Kim D, Galivanche AR, David WB, Justen MA, Moushey AM, Sheth AH, Paranjpe MD, Grauer JN. Analysis of the Frequency, Characteristics, and Reasons for Termination of Spine-related Clinical Trials. Clinical Spine Surgery A Spine Publication 2022, 35: e596-e600. PMID: 35351841, DOI: 10.1097/bsd.0000000000001323.Peer-Reviewed Original ResearchMeSH KeywordsClinical Trials as TopicCross-Sectional StudiesDatabases, FactualHumansOdds RatioRegistriesSpineConceptsClinical trialsTrial terminationTrial characteristicsMultivariate analysisCross-sectional analysisInvestigation of drugsInsufficient accrualResults databaseInterventional studyDetermine predictorsClinical studiesBACKGROUND DATACommon reasonAssess reasonsRecruitment statusTrialsPredictors of terminationSearch termsSpineCompletion ratesRegistryPredictorsStudyTermination
2021
Long-term Corticosteroid Use Independently Correlates With Complications After Posterior Lumbar Spine Surgery.
Kebaish KJ, Galivanche AR, Varthi AG, Ottesen TD, Rubin LE, Grauer JN. Long-term Corticosteroid Use Independently Correlates With Complications After Posterior Lumbar Spine Surgery. Orthopedics 2021, 44: 172-179. PMID: 34039214, DOI: 10.3928/01477447-20210416-01.Peer-Reviewed Original ResearchConceptsLong-term corticosteroid usePosterior lumbar spine surgeryPosterior lumbar surgeryLumbar spine surgeryPerioperative adverse outcomesCorticosteroid useAdverse eventsLumbar surgerySpine surgeryPropensity matchingAdverse outcomesNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseMinor adverse eventsEffect of immunosuppressionImprovement Program databaseLong-term corticosteroidsSerious adverse eventsBody mass indexMultiple surgical specialtiesAnesthesiologists classComparable patientsPerioperative outcomesSurgical factorsMore patients
2020
Thirty-Day Readmissions After Aseptic Revision Total Hip Arthroplasty: Rates, Predictors, and Reasons Vary by Surgical Indication
Pathak N, Kahlenberg CA, Moore HG, Sculco PK, Grauer JN. Thirty-Day Readmissions After Aseptic Revision Total Hip Arthroplasty: Rates, Predictors, and Reasons Vary by Surgical Indication. The Journal Of Arthroplasty 2020, 35: 3673-3678. PMID: 32684401, DOI: 10.1016/j.arth.2020.06.069.Peer-Reviewed Original ResearchConceptsNational Surgical Quality Improvement ProgramThirty-day readmissionTotal hip arthroplastyRecurrent dislocationSurgical indicationsAseptic looseningPeriprosthetic fracturesPostoperative dislocationHip arthroplastyAseptic revision total hip arthroplastyMultivariate analysisPatients meeting inclusion criteriaSurgical Quality Improvement ProgramRevision total hip arthroplastyDifferent surgical indicationsPostoperative care pathwaysMeeting inclusion criteriaQuality Improvement ProgramFurther multivariate analysisAseptic indicationsFracture cohortPostoperative predictorsReadmission ratesReadmission riskCare pathway
2018
What Is the Adverse Event Profile After Prophylactic Treatment of Femoral Shaft or Distal Femur Metastases?
McLynn RP, Ondeck NT, Grauer JN, Lindskog DM. What Is the Adverse Event Profile After Prophylactic Treatment of Femoral Shaft or Distal Femur Metastases? Clinical Orthopaedics And Related Research® 2018, 476: 2381-2388. PMID: 30260860, PMCID: PMC6259894, DOI: 10.1097/corr.0000000000000489.Peer-Reviewed Original ResearchMeSH KeywordsAgedBlood TransfusionDatabases, FactualDiaphysesFemaleFemoral FracturesFemurFracture FixationFractures, SpontaneousHumansLength of StayLogistic ModelsMaleMiddle AgedMultivariate AnalysisNeoplasm MetastasisOdds RatioOperative TimePatient DischargePostoperative ComplicationsProspective StudiesRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeConceptsBody mass indexPathologic fractureAdverse eventsProphylactic treatment groupProphylactic treatmentBlood transfusionDisseminated cancerFemoral shaftComplication profileFracture groupFunctional outcomeProphylactic fixationDistal femurTreatment groupsNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseGreater body mass indexPerioperative complication profileProphylactic surgical stabilizationProphylactic surgical treatmentPostoperative adverse eventsAdverse event profileCurrent Procedural Terminology codesImprovement Program databaseMajor adverse eventsDialysis Patients Undergoing Total Knee Arthroplasty Have Significantly Increased Odds of Perioperative Adverse Events Independent of Demographic and Comorbidity Factors
Ottesen TD, Zogg CK, Haynes MS, Malpani R, Bellamkonda KS, Grauer JN. Dialysis Patients Undergoing Total Knee Arthroplasty Have Significantly Increased Odds of Perioperative Adverse Events Independent of Demographic and Comorbidity Factors. The Journal Of Arthroplasty 2018, 33: 2827-2834. PMID: 29754981, DOI: 10.1016/j.arth.2018.04.012.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overArthroplasty, Replacement, KneeComorbidityElective Surgical ProceduresFemaleHumansInpatientsLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPatient DischargePatient ReadmissionPostoperative ComplicationsQuality ImprovementRegression AnalysisRenal DialysisReoperationRetrospective StudiesRisk AssessmentConceptsTotal knee arthroplastyDialysis-dependent patientsAdverse eventsPatient demographicsDialysis patientsAdverse outcomesKnee arthroplastyNational Surgical Quality Improvement Program databaseOverall healthRisk-adjusted logistic regressionElective total knee arthroplastyQuality Improvement Program databaseImprovement Program databaseMinor adverse eventsNational inpatient databaseSevere adverse eventsBone health statusNondialysis cohortNondialysis patientsPerioperative periodTKA patientsAdult patientsPreoperative riskComorbidity factorsInstitutional cohort
2017
Results of Database Studies in Spine Surgery Can Be Influenced by Missing Data
Basques BA, McLynn RP, Fice MP, Samuel AM, Lukasiewicz AM, Bohl DD, Ahn J, Singh K, Grauer JN. Results of Database Studies in Spine Surgery Can Be Influenced by Missing Data. Clinical Orthopaedics And Related Research® 2017, 475: 2893-2904. PMID: 27896677, PMCID: PMC5670041, DOI: 10.1007/s11999-016-5175-7.Peer-Reviewed Original ResearchMeSH KeywordsComorbidityData AccuracyData CollectionData MiningDatabases, FactualDecision Support TechniquesHumansLength of StayLogistic ModelsMultivariate AnalysisOdds RatioOperative TimeOrthopedic ProceduresPostoperative ComplicationsPredictive Value of TestsProcess Assessment, Health CareRetrospective StudiesRisk AssessmentRisk FactorsSpinal DiseasesSpineTime FactorsTreatment OutcomeUnited StatesConceptsACS-NSQIP databaseAdverse eventsPreoperative laboratory valuesRisk factorsSpine surgeryOperating room timeLaboratory valuesSpine studiesACS-NSQIPDatabase studyRoom timeReference rangeQuality Improvement Program databasePerioperative laboratory valuesVariable reference rangesAnterior cervical discectomyImprovement Program databaseMost risk factorsLength of stayLarge database studiesDifferent risk factorsEffect sizeCervical discectomyMedical comorbiditiesGreater effect sizeIncidence of and Risk Factors for Inpatient Stroke After Hip Fractures in the Elderly.
Samuel AM, Diaz-Collado PJ, Szolomayer LK, Nelson SJ, Webb ML, Lukasiewicz AM, Grauer JN. Incidence of and Risk Factors for Inpatient Stroke After Hip Fractures in the Elderly. Orthopedics 2017, 41: e27-e32. PMID: 29136256, DOI: 10.3928/01477447-20171106-04.Peer-Reviewed Original ResearchConceptsInpatient strokeSerious adverse eventsHip fractureAdverse eventsRisk factorsNational Trauma Data BankIsolated hip fractureHigh-risk patientsAssociation of strokeSystolic blood pressureCoronary artery diseaseTrauma Data BankRisk of mortalityIdentifies risk factorsInpatient complicationsPrior strokeInpatient outcomesElderly patientsArtery diseaseBlood pressureRetrospective reviewInclusion criteriaPatientsMultivariate analysisVigilant care
2014
Complication Rates Following Elective Lumbar Fusion in Patients With Diabetes
Golinvaux NS, Varthi AG, Bohl DD, Basques BA, Grauer JN. Complication Rates Following Elective Lumbar Fusion in Patients With Diabetes. Spine 2014, 39: 1809-1816. PMID: 25010098, DOI: 10.1097/brs.0000000000000506.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedChi-Square DistributionDatabases, FactualDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Elective Surgical ProceduresFemaleHumansHypoglycemic AgentsInsulinLength of StayLogistic ModelsLumbar VertebraeMaleMiddle AgedMultivariate AnalysisOdds RatioPatient ReadmissionPostoperative ComplicationsRetrospective StudiesRisk FactorsSpinal FusionTime FactorsTreatment OutcomeUnited StatesYoung AdultConceptsInsulin-dependent diabetes mellitusLumbar fusion surgeryDiabetes mellitusPostoperative complicationsFusion surgeryLumbar fusionSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseElective lumbar fusion surgeryQuality Improvement Program databaseEffects of NIDDMVentilator-assisted respirationWound-related infectionsAdverse postoperative outcomesRetrospective cohort studyImprovement Program databaseUrinary tract infectionDependent diabetes mellitusElective lumbar fusionPreoperative risk stratificationRisk of deathCommon chronic diseasesLength of stayCounseling of patientsUnplanned intubationPatient Factors Are Associated With Poor Short-term Outcomes After Posterior Fusion for Adolescent Idiopathic Scoliosis
Basques BA, Bohl DD, Golinvaux NS, Smith BG, Grauer JN. Patient Factors Are Associated With Poor Short-term Outcomes After Posterior Fusion for Adolescent Idiopathic Scoliosis. Clinical Orthopaedics And Related Research® 2014, 473: 286-294. PMID: 25201091, PMCID: PMC4390920, DOI: 10.1007/s11999-014-3911-4.Peer-Reviewed Original ResearchConceptsSevere adverse eventsLength of stayAdolescent idiopathic scoliosisAdverse eventsSurgical site infectionPerioperative morbiditySite infectionIdiopathic scoliosisSurgeons National Surgical Quality Improvement ProgramNational Surgical Quality Improvement ProgramExtended LOSPoor short-term outcomeSurgical Quality Improvement ProgramInitial hospital stayResultsTwenty-seven patientsManagement of obesityIndividual adverse eventsShort-term outcomesTotal hospital costsMultivariate logistic regressionQuality Improvement ProgramHospital stayHospital readmissionNinety-fifth percentileOperative time