2023
Timing of Adverse Events Within 90 Days of Hip Fracture Surgery: A Database Study
Kammien A, Ratnasamy P, Caruana D, Grauer J. Timing of Adverse Events Within 90 Days of Hip Fracture Surgery: A Database Study. Journal Of The American Academy Of Orthopaedic Surgeons 2023, 31: 245-251. PMID: 36821080, DOI: 10.5435/jaaos-d-22-00368.Peer-Reviewed Original ResearchConceptsHip fracture surgeryTime of diagnosisAdverse eventsFracture surgeryDay 31Hip fracture surgery patientsElixhauser comorbidity index scoreAcute kidney injuryCommon adverse eventsComorbidity Index scorePatients 65 yearsPostoperative day 0Surgical site infectionUrinary tract infectionPostoperative day 30Specific adverse eventsKidney injuryCardiac eventsSurgery patientsTract infectionsVenous thromboembolismSite infectionPatient counselingNotable morbidityDatabase studySecond Primary Malignancies of the Bones and Joints: More Common than Expected in Osteosarcoma Patients
Freedman I, Dowd H, Dhodapkar M, Halperin S, Grauer J. Second Primary Malignancies of the Bones and Joints: More Common than Expected in Osteosarcoma Patients. JAAOS Global Research And Reviews 2023, 7: e22.00275. PMID: 36695170, PMCID: PMC9875998, DOI: 10.5435/jaaosglobal-d-22-00275.Peer-Reviewed Original ResearchConceptsSecond primary malignanciesStandardized incidence ratiosOsteosarcoma survivorsPrimary malignancyCommon second primary malignancyNational Cancer Institute's SurveillanceEnd Results 18 databaseCommon primary bone tumorPrimary bone tumorsPopulation-level dataIncidence ratiosOverall incidenceOsteosarcoma patientsPatient populationExcess riskBone tumorsAnatomic locationLong-term eventsOsteosarcoma casesPatientsYoung adultsTumorsSoft tissueMalignancyOsteosarcomaIncidental Durotomy After Posterior Lumbar Decompression Surgery Associated With Increased Risk for Venous Thromboembolism
Gouzoulis M, Joo P, Caruana D, Kammien A, Rubio D, Grauer J. Incidental Durotomy After Posterior Lumbar Decompression Surgery Associated With Increased Risk for Venous Thromboembolism. Journal Of The American Academy Of Orthopaedic Surgeons 2023, 31: e445-e450. PMID: 36727948, DOI: 10.5435/jaaos-d-22-00917.Peer-Reviewed Original ResearchConceptsLumbar decompression surgeryPosterior lumbar decompression surgeryRisk of VTEVenous thromboembolismIncidental durotomyDecompression surgeryMultivariate analysisOdds of VTETiming of VTEMore VTEDecompression patientsDurotomy groupPatient demographicsPulmonary embolismAdult patientsDegenerative etiologyBed restLumbar laminectomyPatient recoveryUnivariate analysisSpinal surgeryAdministrative codingDurotomySurgeryPatients
2022
Incidence, Timing, and Predictors of Hip Dislocation After Primary Total Hip Arthroplasty for Osteoarthritis
Gillinov SM, Joo PY, Zhu JR, Moran J, Rubin LE, Grauer JN. Incidence, Timing, and Predictors of Hip Dislocation After Primary Total Hip Arthroplasty for Osteoarthritis. Journal Of The American Academy Of Orthopaedic Surgeons 2022, 30: 1047-1053. PMID: 35947825, PMCID: PMC9588560, DOI: 10.5435/jaaos-d-22-00150.Peer-Reviewed Original ResearchConceptsPrimary total hip arthroplastyTotal hip arthroplastyElixhauser Comorbidity IndexBody mass indexComorbidity indexMass indexHip dislocationRevision surgeryRisk factorsHip arthroplastyIndex total hip arthroplastyHigher Elixhauser comorbidity indexPrimary THA patientsFirst-time dislocationCumulative incidenceMost patientsPostoperative dataTHA patientsRecurrent episodesControl subjectsFemale sexLarge cohortPatientsMultivariate analysisYounger ageIncidence, Timing, and Risk Factors for 5-Year Revision Surgery After Autologous Chondrocyte Implantation in 533 Patients
Gillinov SM, Fosam A, Burroughs PJ, Schneble CA, McLaughlin WM, Moran J, Jimenez AE, Grauer JN, Medvecky MJ. Incidence, Timing, and Risk Factors for 5-Year Revision Surgery After Autologous Chondrocyte Implantation in 533 Patients. The American Journal Of Sports Medicine 2022, 50: 2893-2899. PMID: 35916771, DOI: 10.1177/03635465221111115.Peer-Reviewed Original ResearchConceptsBony realignment proceduresAutologous chondrocyte implantationBody mass indexPrimary Autologous Chondrocyte ImplantationRevision surgeryRisk factorsRealignment proceduresPostoperative yearKnee arthroplastyFemale sexChondrocyte implantationECI scoresElixhauser comorbidity index scoreChondral defectsComorbidity Index scoreKaplan-Meier analysisLarge national cohortUnicompartmental knee arthroplastyTotal knee arthroplastyOsteochondral allograft transplantationLevel of evidenceOsteochondral autograft transferArticular cartilage proceduresFull-thickness chondral defectsChondral procedures
2020
Orthopaedic Injuries Associated With Cell Phone Use Resulting in Emergency Department Visits: A 20-Year Analysis
Moore HG, Halperin SJ, Berson ER, Burroughs PJ, Paskhover B, Grauer JN. Orthopaedic Injuries Associated With Cell Phone Use Resulting in Emergency Department Visits: A 20-Year Analysis. Journal Of The American Academy Of Orthopaedic Surgeons 2020, 29: 571-579. PMID: 32947349, DOI: 10.5435/jaaos-d-20-00639.Peer-Reviewed Original ResearchConceptsOrthopedic injuriesED visitsAge groupsElectronic Injury Surveillance SystemSprains/strainsInjury Surveillance SystemStandard deviation ageProportion of injuriesEmergency Department DatabasesType of injuryPublic health educationDeviation ageEmergency departmentInjury typeDepartment databaseSuch injuriesInclusion criteriaAnatomic locationHealth educationInjuryCell phone useMarked increaseCommon typeBody partsPhone useIncidence, predictors, and timing of post-operative stroke following elective total hip arthroplasty and total knee arthroplasty
Haynes MS, Alder KD, Bellamkonda K, Kuzomunhu L, Grauer JN. Incidence, predictors, and timing of post-operative stroke following elective total hip arthroplasty and total knee arthroplasty. PLOS ONE 2020, 15: e0239239. PMID: 32941539, PMCID: PMC7498016, DOI: 10.1371/journal.pone.0239239.Peer-Reviewed Original ResearchConceptsTotal knee arthroplastyTotal hip arthroplastyIndependent risk factorPostoperative day twoPostoperative strokeKnee arthroplastyRisk factorsHip arthroplastyElective primary total hip arthroplastyTHA/TKANational Surgical Quality Improvement databaseElective total hip arthroplastyDay twoPrimary total hip arthroplastyPostoperative day ninePost-operative strokeTiming of strokeHigher American SocietyIncidence of strokePostoperative day oneMajority of strokesQuality improvement databaseRetrospective comparative studyAnesthesiologists (ASA) scoreCouncil patients
2019
Incidence, Risk Factors, and Clinical Implications of Postoperative Hematoma Requiring Reoperation Following Anterior Cervical Discectomy and Fusion
Bovonratwet P, Fu MC, Tyagi V, Bohl DD, Ondeck NT, Albert TJ, Grauer JN. Incidence, Risk Factors, and Clinical Implications of Postoperative Hematoma Requiring Reoperation Following Anterior Cervical Discectomy and Fusion. Spine 2019, Publish Ahead of Print: &na;. PMID: 30247374, DOI: 10.1097/brs.0000000000002885.Peer-Reviewed Original ResearchConceptsAnterior cervical discectomyRisk factorsPostoperative hematomaCervical discectomyNational Surgical Quality Improvement Program databaseClinical implicationsPreoperative international normalized ratioQuality Improvement Program databaseDeep wound infectionHigh-risk patientsImprovement Program databaseDevelopment of hematomaInternational normalized ratioLarge cohort studyOccurrence of hematomaACDF patientsPreoperative anemiaVentilator requirementAnesthesiologists classificationPostoperative lengthCohort studyPerioperative periodCatastrophic complicationPrimary outcomeSubsequent complicationsCardiac Complications Related to Spine Surgery: Timing, Risk Factors, and Clinical Effect.
Bovonratwet P, Bohl DD, Malpani R, Haynes MS, Rubio DR, Ondeck NT, Shultz BN, Mahal AR, Grauer JN. Cardiac Complications Related to Spine Surgery: Timing, Risk Factors, and Clinical Effect. Journal Of The American Academy Of Orthopaedic Surgeons 2019, 27: 256-263. PMID: 30897607, DOI: 10.5435/jaaos-d-17-00650.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overDatabases, FactualFemaleHeart ArrestHumansIncidenceIntraoperative ComplicationsLength of StayMaleMiddle AgedMonitoring, PhysiologicMultivariate AnalysisMyocardial InfarctionOrthopedic ProceduresPatient ReadmissionPerioperative PeriodPostoperative ComplicationsRisk FactorsSpineTime FactorsYoung AdultConceptsCardiac complicationsSpine surgeryRisk factorsPostoperative periodNational Surgical Quality Improvement Program databaseSurgeons National Surgical Quality Improvement ProgramNational Surgical Quality Improvement ProgramQuality Improvement Program databaseSurgical Quality Improvement ProgramPerioperative cardiac complicationsHigh-risk patientsImprovement Program databaseInsulin-dependent diabetesLarge cohort studyQuality Improvement ProgramPreoperative anemiaPostoperative lengthCohort studyPerioperative periodPrimary outcomeClinical effectsCardiac arrestMyocardial infarctionProgram databaseAmerican College
2018
Incidence and considerations of 90-day readmissions following posterior lumbar fusion
Cui JJ, Gala RJ, Ondeck NT, McLynn RP, Bovonratwet P, Shultz B, Grauer JN. Incidence and considerations of 90-day readmissions following posterior lumbar fusion. The Spine Journal 2018, 19: 631-636. PMID: 30219360, DOI: 10.1016/j.spinee.2018.09.004.Peer-Reviewed Original ResearchConceptsPosterior lumbar fusionDays of dischargeReadmission ratesBaseline readmission ratesHuman Investigation CommitteeAdmission ratesDay readmissionLumbar fusionUtilization Project Nationwide Readmissions DatabaseAverage daily admission rateBaseline admission rateBundled payment plansNationwide Readmissions DatabaseHospital admission dataAverage admission rateDaily admission ratesCalendar yearCurrent quality metricsPLF patientsPatient demographicsPostoperative dayRetrospective studyPatient counselingPatient outcomesSpine surgeryIncidence, Risk Factors, and Impact of Clostridium difficile Colitis After Spine Surgery
Bovonratwet P, Bohl DD, Russo GS, Ondeck NT, Singh K, Grauer JN. Incidence, Risk Factors, and Impact of Clostridium difficile Colitis After Spine Surgery. Spine 2018, 43: 861-868. PMID: 28953711, DOI: 10.1097/brs.0000000000002430.Peer-Reviewed Original ResearchConceptsClostridium difficile colitisDifficile colitisIndependent risk factorSpine surgical proceduresRisk factorsSpine surgerySurgical proceduresPosterior lumbar fusion proceduresPost-hospitalization followSpine surgery patientsHigh-risk patientsLarge cohort studyLumbar fusion proceduresPre-existing infectionLarge national databasePostoperative lengthCohort studyNSQIP databasePostoperative periodSurgery patientsPrimary outcomeRetrospective studyDifficile infectionClinical impactInfection diagnosisIncidence of and Risk Factors for Knee Collateral Ligament Injuries With Proximal Tibia Fractures: A Study of 32,441 Patients.
Samuel AM, Diaz-Collado PJ, Szolomayer LK, Wiznia DH, Chan WW, Lukasiewicz AM, Basques BA, Bohl DD, Grauer JN. Incidence of and Risk Factors for Knee Collateral Ligament Injuries With Proximal Tibia Fractures: A Study of 32,441 Patients. Orthopedics 2018, 41: e268-e276. PMID: 29451942, DOI: 10.3928/01477447-20180213-03.Peer-Reviewed Original ResearchConceptsCollateral ligament injuriesProximal tibia fracturesLigament injuryTibia fracturesRisk factorsCollateral ligamentLateral collateral ligament injuryMedial collateral ligament injuryNational Trauma Data BankInpatient adverse eventsLonger hospital stayInjury Severity ScoreDistal femur fracturesChronic knee instabilityTrauma Data BankKnee collateral ligamentsHospital stayInpatient outcomesAdverse eventsSimultaneous injuryFemur fracturesSeverity scoreKnee instabilityHigher oddsMultivariate analysisHow Common—and How Serious— Is Clostridium difficile Colitis After Geriatric Hip Fracture? Findings from the NSQIP Dataset
Bovonratwet P, Bohl DD, Russo GS, Ondeck NT, Nam D, Della Valle CJ, Grauer JN. How Common—and How Serious— Is Clostridium difficile Colitis After Geriatric Hip Fracture? Findings from the NSQIP Dataset. Clinical Orthopaedics And Related Research® 2018, 476: 453-462. PMID: 29443839, PMCID: PMC6260047, DOI: 10.1007/s11999.0000000000000099.Peer-Reviewed Original ResearchConceptsHip fracture surgeryClostridium difficile colitisDifficile colitisGeriatric hip fracturesChronic care facilitiesHip fractureFracture surgeryPostoperative lengthGeriatric patientsHigh riskPreoperative anemiaCurrent smokersCare facilitiesStrict hand hygieneProphylactic antibiotic regimensFuture prospective studiesHospital quality metricsLarge database studiesStepwise multivariate modelLarge national databasePostdischarge dataAntibiotic regimensInfectious diagnosisPreoperative factorsProphylactic antibioticsAseptic revision total hip arthroplasty in the elderly : quantifying the risks for patients over 80 years old.
Bovonratwet P, Malpani R, Ottesen TD, Tyagi V, Ondeck NT, Rubin LE, Grauer JN. Aseptic revision total hip arthroplasty in the elderly : quantifying the risks for patients over 80 years old. The Bone & Joint Journal 2018, 100-B: 143-151. PMID: 29437055, DOI: 10.1302/0301-620x.100b2.bjj-2017-0895.r1.Peer-Reviewed Original ResearchConceptsAseptic revision total hip arthroplastyRevision total hip arthroplastyTotal hip arthroplastySerious adverse eventsAdverse eventsRisk factorsProcedural characteristicsHip arthroplastyNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseImprovement Program databaseIndependent risk factorUrinary tract infectionMultivariate regression analysisAnesthesiologists (ASA) scoreMedical optimizationPerioperative complicationsPerioperative mortalityPostoperative complicationsTract infectionsYounger patientsBlood transfusionGeneral anesthesiaVulnerable patientsBone JointTotal Disc Arthroplasty Versus Anterior Interbody Fusion in the Lumbar Spine Have Relatively a Few Differences in Readmission and Short-term Adverse Events
Shultz BN, Wilson AT, Ondeck NT, Bovonratwet P, McLynn RP, Cui JJ, Grauer JN. Total Disc Arthroplasty Versus Anterior Interbody Fusion in the Lumbar Spine Have Relatively a Few Differences in Readmission and Short-term Adverse Events. Spine 2018, 43: e52-e59. PMID: 28723873, DOI: 10.1097/brs.0000000000002337.Peer-Reviewed Original ResearchConceptsAnterior lumbar interbody fusionTotal disc arthroplastyAdverse eventsBlood transfusionOperative timeInterbody fusionRisk factorsSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseShort-term adverse eventsQuality Improvement Program databaseShort-term clinical outcomesLong-term functional outcomeLumbar total disc arthroplastySerious adverse eventsImprovement Program databaseAnterior interbody fusionIndividual adverse eventsStand-alone Anterior Lumbar Interbody FusionGeneral health outcomesPotential risk factorsLumbar interbody fusionMultivariate Poisson regressionPerioperative outcomesPostoperative length
2017
Incidence of and Risk Factors for Inpatient Stroke After Hip Fractures in the Elderly.
Samuel AM, Diaz-Collado PJ, Szolomayer LK, Nelson SJ, Webb ML, Lukasiewicz AM, Grauer JN. Incidence of and Risk Factors for Inpatient Stroke After Hip Fractures in the Elderly. Orthopedics 2017, 41: e27-e32. PMID: 29136256, DOI: 10.3928/01477447-20171106-04.Peer-Reviewed Original ResearchConceptsInpatient strokeSerious adverse eventsHip fractureAdverse eventsRisk factorsNational Trauma Data BankIsolated hip fractureHigh-risk patientsAssociation of strokeSystolic blood pressureCoronary artery diseaseTrauma Data BankRisk of mortalityIdentifies risk factorsInpatient complicationsPrior strokeInpatient outcomesElderly patientsArtery diseaseBlood pressureRetrospective reviewInclusion criteriaPatientsMultivariate analysisVigilant careWhich Pediatric Orthopaedic Procedures Have the Greatest Risk of Adverse Outcomes?
Basques BA, Lukasiewicz AM, Samuel AM, Webb ML, Bohl DD, Smith BG, Grauer JN. Which Pediatric Orthopaedic Procedures Have the Greatest Risk of Adverse Outcomes? Journal Of Pediatric Orthopaedics 2017, 37: 429-434. PMID: 26558959, DOI: 10.1097/bpo.0000000000000683.Peer-Reviewed Original ResearchConceptsPediatric orthopaedic proceduresCommon pediatric orthopaedic proceduresAdverse outcomesAdverse eventsOrthopedic proceduresSpinal fusionPediatric patientsPediatric databaseNational Surgical Quality Improvement Program Pediatric databaseSurgeons National Surgical Quality Improvement Program Pediatric databaseNSQIP-Pediatric databasePediatric orthopedic patientsRetrospective cohort studyMultiple patient characteristicsPosterior spinal fusionPediatric patient samplesDifferent orthopedic proceduresASA classCohort studyPerioperative safetyPatient characteristicsNonidiopathic scoliosisOrthopedic patientsOperative characteristicsExternal fixationIncidence, Risk Factors, and Impact of Clostridium difficile Colitis Following Primary Total Hip and Knee Arthroplasty
Bovonratwet P, Bohl DD, Malpani R, Nam D, Della Valle CJ, Grauer JN. Incidence, Risk Factors, and Impact of Clostridium difficile Colitis Following Primary Total Hip and Knee Arthroplasty. The Journal Of Arthroplasty 2017, 33: 205-210.e1. PMID: 28870746, DOI: 10.1016/j.arth.2017.08.004.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overArthroplasty, Replacement, HipArthroplasty, Replacement, KneeClostridioides difficileColitisEnterocolitis, PseudomembranousFemaleHumansIncidenceKnee JointMaleMiddle AgedPatient DischargePostoperative ComplicationsQuality ImprovementRetrospective StudiesRisk FactorsUnited StatesConceptsNational Surgical Quality Improvement ProgramSurgical Quality Improvement ProgramDifficile colitisPrimary total hipRisk factorsQuality Improvement ProgramPrimary THATotal hipProcedural risk factorsClostridium difficile colitisHigh-risk patientsUrinary tract infectionInfectious risk factorsPoisson multivariate regressionPreoperative anemiaPerioperative antibioticsPostoperative periodTract infectionsPrimary outcomeSubstantial morbidityKnee arthroplastyColitisPatientsClinical implicationsHospital qualityDoes Preoperative Pneumonia Affect Complications of Geriatric Hip Fracture Surgery?
Patterson JT, Bohl DD, Basques BA, Arzeno AH, Grauer JN. Does Preoperative Pneumonia Affect Complications of Geriatric Hip Fracture Surgery? The American Journal Of Orthopedics 2017, 46: e177-e185. PMID: 28666049.Peer-Reviewed Original ResearchConceptsHip fracture repairHip fracture patientsGeriatric hip fracture patientsHip fracture surgeryPreoperative pneumoniaFracture patientsAdverse eventsFracture repairFracture surgeryAdverse outcomesNational Surgical Quality Improvement Program databaseEarly hip fracture surgeryGeriatric hip fracture surgeryQuality Improvement Program databaseChronic obstructive pulmonary diseaseUnderweight body mass indexSerious adverse eventsImprovement Program databaseObstructive pulmonary diseaseTime of surgeryBody mass indexPreoperative anemiaDelaying surgeryRetrospective cohortHip fracture
2016
Demographics, Mechanisms of Injury, and Concurrent Injuries Associated With Calcaneus Fractures: A Study of 14 516 Patients in the American College of Surgeons National Trauma Data Bank
Bohl DD, Ondeck NT, Samuel AM, Diaz-Collado PJ, Nelson SJ, Basques BA, Leslie MP, Grauer JN. Demographics, Mechanisms of Injury, and Concurrent Injuries Associated With Calcaneus Fractures: A Study of 14 516 Patients in the American College of Surgeons National Trauma Data Bank. Foot & Ankle Specialist 2016, 10: 402-410. PMID: 27895200, DOI: 10.1177/1938640016679703.Peer-Reviewed Original ResearchConceptsNational Trauma Data BankSurgeons National Trauma Data BankTrauma Data BankCalcaneus fracturesConcurrent injuriesNonorthopaedic injuriesSpine fracturesAmerican CollegeMechanism of injuryLower extremity fracturesLumbar spine fracturesCommon comorbiditiesFracture patientsExtremity fracturesOrgan injuryRetrospective reviewNational sampleHead injuryHigh incidenceInjury mechanismPatientsLevel IIIInjuryHospital departmentsStrong association